Universitat Internacional de Catalunya

Endocrinology and Nutrition

Endocrinology and Nutrition
4.5
12076
4
First semester
OB
Main language of instruction: Catalan

Teaching staff


marecasens@uic.es

Introduction

In the event that the health authorities announce a new period of confinement due to the evolution of the health crisis caused by COVID-19, the teaching staff will promptly communicate how this may effect the teaching methodologies and activities as well as the assessment.


 

In the case that the sanitary authorities decreed a new period of confinement due to the evolution of the sanitary crisis caused by COVID-19, the professors must communicate in a timely manner the possible affectations to the methodologies and formative activities, also in the d 'system. assessed.

Endocrinology and Nutrition is that medical specialty that deals with the study and treatment of diseases of the endocrine glands, metabolism and all aspects related to nutritional status. It includes the basic and practical knowledge of diagnostic techniques, dietary and therapeutic measures and all aspects of Preventive Medicine related to these fields.

 

Pre-course requirements

The students must have approved the subject "Structure and function of the endocrine system". As well as, the basic subjects of "Biochemistry", "Cell Biology", "Molecular Biology", "Biophysics", "Histology", "Pathological Anatomy" and "Pharmacology."

Objectives

General objective

During the training period, the student must acquire the ability to recognize the main problems of endocrine pathology, guide their diagnosis (in particular in the most common pathologies), use current diagnostic methods following a logical and rational reasoning and, finally, guide the therapeutic approach. It will also be important to recognize signs of alarm that indicate the need for urgent hospital care.

Specific objectives

- Recognize, diagnose and guide the management of the main pathologies of the endocrine system

  • Obesity and malnutrition.
  • Disorders of the metabolism of lipoproteins.
  • Diabetes Mellitus. Hyperglycemia. Hypoglycemia
  • Hyperthyroidism. Hypothyroidism. Thyroiditis Goose and thyroid nodule. Thyroid cancer
  • Sexual development. Hirsutism and virilization. Gynecomastia.
  • Hypercalcemia and Hypocalcemia.
  • Diseases of the crust and adrenal medulla.
  • Hypothalamic-pituitary pathology.

Competences/Learning outcomes of the degree programme

  • 04 - Develop professional practice with respect for patient autonomy, beliefs and culture.
  • 10 - To understand and recognise the agents and risk factors which determine health status, and learn how they determine the symptoms and natural development of acute or chronic diseases in individuals and populations.
  • 12 - Understanding the foundations for action, the indications and efficacy of therapeutic interventions, based on available scientific evidence.
  • 15 - Ability to formulate an initial diagnosis and establish a rationalised diagnostic strategy.
  • 16 - Recognize and deal with situations that put life in immediate danger and those that require immediate attention.
  • 17 - Establish the diagnosis, prognosis and treatment, applying principles based on the best information possible and safe clinical practice..
  • 18 - To indicate the most appropriate (pharmacological, surgical, psychological, social or other) treatments that are pertinent to the most prevalent procedures, in terms of rehabilitation and also terminally ill patients, including an evaluation of their effectiveness.
  • 19 - Propose preventive measures appropriate to each clinical situation.
  • 25 - Recognize the determinants of public health; genetic and sex-dependent lifestyle, demographic, environmental, social, economic, psychological and cultural determinants.

Learning outcomes of the subject

At the end of the course the student will be able to:

  • Identify endocrine-metabolic diseases and know their therapeutic management.
  • Know the indications of the determination of hormonal parameters and know how to interpret them.
  • Argue for the application of complementary examinations in the common pathologies and to know how to interpret them.
  • Know how to perform a differential diagnosis.
  • Know the management of the main endocrinological urgencies (severe hypoglycaemia, diabetic ketoacidosis, hyperosmolar coma, hypercalcemia, myxedema coma, acute adrenal crisis…).
  • Describe in understandable way for the patient and / or relative an endocrinological pathology, treatment and prognosis.

Teaching and learning activities

In blended



Master Classes

1. Introduction to the endocrine system. Nature of hormones. Families of hormonal receptors and action. Feed-back regulation system. Disorders due to excess, deficiency or resistance.

2. Hypothalamic-Adenohypophysis I. Hypothalamic and pituitary insufficiency, genetic causes and acquired. Non-tumoral lesions in the Sella: vascular, infectious, inflammatory, cysts, incidentalomes. Craniopharyngioma.

3. Thyroid.  Physiological record: synthesis of thyroid hormones and regulation of the thyroid axis. Endemic goiter nodule goiter. Hypothyroidism: Etiology, clinical, diagnosis and treatment. Myxedema coma. Hyperthyroidism: etiology, clinical manifestations, diagnosis and treatment. Bassedow's disease. Thyroid storm, Hyperthyroidism and hypothyroidism in pregnancy.

4. Phospho-calcic metabolism and parathyroid pathology. Physiology of PTH secretion and calcitonin. Hypercalcemia: etiology and clinical practice. Hyperparathyroidism Other causes of hypercalcemia and diagnosis. Hypocalcemia: causes and clinical. Hypoparathyroidism. Pseudohypoparathyroidism. Resistance to the action of PTH.

5. Adrenal cortex I. Physiology of secretion of adrenal hormones. Primary adrenal insufficiency of autoimmune cause (clinical, diagnosis and treatment). Other causes of primary adrenal insufficiency. Adrenal crisis Hypoaldosteronism.

6. Adrenal cortex II. Glucocorticoid hypersecretion syndromes: Etiology, clinic features, diagnosis and treatment. Primary and secondary hyperaldosteronism, Hyperdeoxycorticosterone and pseudohyperaldosteronism. Incidental adrenal masses. Adrenal medulla Synthesis of catecholamines. Pheochromocytoma: Clinical features, diagnosis and treatment.

7. Multiple endocrine neoplasia. Gastroenteropancreatic endocrine tumors. Carcinoid Sdme. Classification of multiple endocrine neoplasm syndromes. Clinic, genetic study, monitoring and treatment.

8. Diabetes introduction. Definition, classification of diabetes and diagnosis. Diabetes type 1. Epidemiology. Pathogenesis of type 1 diabetes. Treatment objectives. Monitoring and treatment of hyperglycaemia.

9. Diabetes type 2. Epidemiology. Pathophysiology. Treatment of type 2 diabetes: lifestyle changes, oral treatment, GLP-1 analogues and insulinization.

10. Chronic Diabetic Complications: Microangiopathic (Nephropathy, Retinopathy and Neuropathy). Epidemiology, pathogenesis, diagnosis, treatment. Macroangiopathic. Epidemiology, pathogenesis, diagnosis and treatment.

11. Disorders of lipid metabolism. Epidemiology. Diagnosis Classification Treatment of dyslipidemia.

12. Clinical Nutrition. Nutritional requirements (macronutrients and micronutrients). Evaluation of nutritional status. Malnutrition: definition, classification, pathophysiology. Treatment. Bases of nutritional support.

13. Obesity Definition Etiopathogenetic. Pathophysiology. Diagnosis Evaluation of the obese patient and integral treatment.

14. Pathological anatomy of the endocrine system.

 

Virtual:

  • Hypoglycaemia in diabetes mellitus.
  • Clinical case nutrition resolution.


Divides classes.

  1. Part I class: Thyroid cancer.

2. Part II class: Adenohypophysis Hyperfunction.

3. Part III class: Neurohypophysis.

4. Part IV class: Acute complications of diabetes (severe hypoglycaemia, diabetic ketoacidosis, hyperosmolar coma).

5. Part V class: Adrenal.

6. Part VI class: Endocrine surgery (parathyroid, adrenal, thyroid, bariatric).

 

Learning Based Problem:

ABP I:  Thyroiditis.

ABP II: Nutrition Therapy for patients With Diabetes

ABP III: Non-insulin pharmacological treatment of type 2 diabetes mellitus.

ABP IV: Histopathology of the Endocrine System.

ABP V: Disorders of sexual development. Primary and secondary hypogonadism.

 

Laboratory skills:

  • LH Diabetes. Insulin regimes.

5 minutes will be left free to enter the master classes, the split class, APB or skills laboratory. Once started, you will not be able to access or have the option to change groups.


Lecture (CM) is online.

Case method (MC), learning based problem and Laboratory practice are face to face.


Evaluation systems and criteria

In blended



Systems and evaluation criteria

The final evaluation of the student will be the sum of the evaluation of the different methodologies used. The percentage weight of each one of them is detailed below:

 - Theoretical evaluation: 60%

partial Exam. Represents 5% of the note.

Final exam. Represents e 55% of the note.

Exams are multiple answer tests with 30 and 60 test questions, respectively, of multiple choice (4 possible answers). It will be discounted for each incorrect answer 0.25 in partial exam and 0,33 in final exam. The exam time will be 0,9 minutes for question. The partial exam does not release material. The possibility of revising the exam per group of 5 questions will be limited, you will not be able to go back to review the previous questions.

The subject are evaluated in the multiple answer exam includes the content of the parted classes, skills lab, virtual learning and sessions Problem-based learning, intranet teaching material and the recommended main bibliography.

The non-attendance to any of the practical sessions or the non-realization of the virtual learning supposes a 0 in the score of that one session. In the second call, the final grade for the course will in no case be accessed for outstanding or honors.

In the second final exam (June/July) represents 55% of the note, partial Exam. represents 5% of the note and Learning Based Problem, the skills lab, virtual learning and clinical case class. A 5 or more will be taken in the second final exam to pass the endocrinology.  In the second final exam, the final grade for the course will in no case be accessed for excellent or more.

It will represent 40% of the final grade. The final grade of the practical methodology will be obtained from the average of:

-          Divided classes.

-          Problem Based Learning.

-          Skills laboratory.

-          Virtual learning

-          At the end of some master classes there will be activities of the basic concepts that will be evaluable

Failure to attend, failure to perform the activity in any of the hands-on sessions, or failure to perform e-learning is a score of 0 for that session.

 

To improve the mark, a series of activities must be carried out that are in Moodle. These activities must be carried out before December 31. Wrong answers do not penalize. Represents a maximum of 1 point. It will only apply in the first convocatory, you must have passed the partial and final exam, and have completed all the online activities.

 

 

Bibliography and resources

- Fauci, Braunwald, Kasper, Hauser, Longo, Jameson, and Loscalzo, Eds. HARRISON PRINCIPIOS DE MEDICINA INTERNA. 17a edición. McGraw Hill, 2009. ISBN: 970-10-6788-6.

- Farreras-Rozman. MEDICINA INTERNA. 19ª edición. Elsevier, 2020.

- Henry M. Kronenberg, Shlomo Melmed, Kenneth S. Polonsky, and P. Reed Larsen. WILLIAMS TEXTBOOK OF ENDOCRINOLOGY. 11th Edition, 2008. ISBN: 978-1-4160-2911-3

Recommended web pages.

Www.sediabetes.org

www.seen.es

www.aace.com

www.thyroidmanager.org

www.endo-society.org

www.endotext.org

www.endocrinologiahoy.com /html/contenido.html

Evaluation period

E: exam date | R: revision date | 1: first session | 2: second session:
  • E1 07/01/2021 17:30h
  • E2 07/07/2021 14:00h