Universitat Internacional de Catalunya
Pulp Regeneration
Other languages of instruction: Catalan, Spanish,
Teaching staff
Introduction
This course will cover the basics of tissue engineering in respect of pulp and different techniques of pulp regeneration.
Pre-course requirements
No previous requirements
Objectives
To recognise the potential for repairing and regenerating pulp.
To understand pulp repair mechanisms.
To understand the mechanisms for pulp regeneration.
To know the types of stem cells involved in the regeneration and repair of pulp.
To understand the different types of growth factor that can be found in the pulp and the dentin.
To know the different types of scaffold in pulp regeneration techniques.
To know disinfection techniques to optimise the possibility of pulp regeneration.
To know the different clinical protocols for revascularisation.
Competences/Learning outcomes of the degree programme
Students will be expected to:
- Demonstrate an ability for self-learning in the development of new instrumental techniques, the acquisition of new scientific concepts and the search for new scientific information.
- Argue and defend their own scientific ideas as well as to listen, analyse, evaluate and respond to the ideas of others.
- Acquire learning skills that allow them to continue studying in a self-directed and autonomous manner.
- Understand how to provide a basis or opportunity for originality in developing and/or applying ideas in a research context.
- Apply acquired knowledge and develop a problem-solving ability in new environments within broader (or multidisciplinary) contexts related to the field of study in question.
- Communicate their knowledge, conclusions and the essential concepts that support them to specialised and non-specialised audiences in a clear and unambiguous way.
- Apply the appropriate diagnostic techniques and correctly interpret the results derived from them.
- Demonstrate the ability to integrate new knowledge acquired through research and study, and deal with complexity.
- Demonstrate the ability to diagnose, prevent pulpoperiapical diseases and keep up-to-date with the diagnostic and therapeutic advances that emerge during their professional lives.
Learning outcomes of the subject
The student will be expected to:
Know the mechanisms, indications, advantages and limitations of pulp repair and regeneration treatments.
Know the different clinical protocols of revascularization and the scientific criteria that justify the use of the different techniques.
Keep up-to-date on progress in the area of pulp regeneration.
Syllabus
Pulp repair mechanisms.
Pulp regeneration mechanisms.
Types of stem cells involved in pulp regeneration and repair.
Types of growth factors involved in pulp regeneration and repair.
Types of scaffolds in pulp regeneration techniques.
Disinfection techniques to optimise the possibility of pulp regeneration.
The clinical protocols of revascularisation.
Bibliography and resources
Francisco Banchs, Martin Trope. Revascularization of Immature Permanent Teeth With Apical Periodontitis: New Treatment Protocol? Volume 30, Issue 4, Pages 196-200, April 2004.
Wataru Sonoyama, Yi Liu, Takayoshi Yamaza, Rocky S. Tuan, Songlin Wang, Songtao Shi, George T.-J. Huang. Characterization of the Apical Papilla and Its Residing Stem Cells from Human Immature Permanent Teeth: A Pilot Study.
Regenerative Endodontics: A Review of Current Status and a Call for Action.
The Application of Tissue Engineering to Regeneration of Pulp and Dentin in Endodontics.
The Hidden Treasure in Apical Papilla: The Potential Role in Pulp/Dentin Regeneration and BioRoot Engineering.
Dental Pulp Tissue Engineering with Stem Cells from Exfoliated Deciduous Teeth.
Immature Teeth With Periradicular Periodontitis or Abscess Undergoing Apexogenesis: A Paradigm Shift.
Regeneration Potential of the Young Permanent Tooth: What Does the Future Hold?
In Vivo Generation of Dental Pulp-like Tissue by Using Dental Pulp Stem Cells, a Collagen Scaffold, and Dentin Matrix Protein 1 after Subcutaneous Transplantation in Mice.
Pulp Revascularization of Immature Dog Teeth With Apical Periodontitis.
Disinfection of Immature Teeth with a Triple Antibiotic Paste.
Biologically Based Treatment of Immature Permanent Teeth with Pulpal Necrosis: A Case Series.
Stem Cell Proliferation Pathways Comparison between Human Exfoliated Deciduous Teeth and Dental Pulp Stem Cells by Gene Expression Profile from Promising Dental Pulp.
Efficacy of Revascularization to Induce Apexification/Apexogenesis in Infected, Nonvital, Immature Teeth: A Pilot Clinical Study.
A Retrospective Evaluation of Radiographic Outcomes in Immature Teeth With Necrotic Root Canal Systems Treated With Regenerative Endodontic Procedures.
Regenerative Treatment of an Immature, Traumatized Tooth With Apical Periodontitis: Report of a Case.
Pulp Revascularization of Immature Teeth With Apical Periodontitis: A Clinical Study.
Regenerative Endodontic Treatment for Necrotic Immature Permanent Teeth.
Tooth Slice–Based Models for the Study of Human Dental Pulp Angiogenesis.
Histologic Characterization of Regenerated Tissues in Canal Space after the Revitalization/Revascularization Procedure of Immature Dog Teeth with Apical Periodontitis.
Periodontal and Endodontic Regeneration.
Cell Survival within Pulp and Periodontal Constructs.
Differentiation Potential of Dental Papilla, Dental Pulp, and Apical Papilla Progenitor Cells.
Inherent Differential Propensity of Dental Pulp Stem Cells Derived from Human Deciduous and Permanent Teeth.
Stem Cell Regulatory Gene Expression in Human Adult Dental Pulp and Periodontal Ligament Cells Undergoing Odontogenic/Osteogenic Differentiation.
Hypoxia-amplified Proliferation of Human Dental Pulp Cells.
Isolation and Characterization of Human Dental Pulp Stem/Stromal Cells From Nonextracted Crown-fractured Teeth Requiring Root Canal Therapy.
The Comparison of the Effect of Endodontic Irrigation on Cell Adherence to Root Canal Dentin.
Regenerative Potential of Dental Pulp.
Guided Tissue Regeneration in Periapical Surgery.