Universitat Internacional de Catalunya

Regenerative Medicine and Tissue Engineering

Regenerative Medicine and Tissue Engineering
3
13510
4
First semester
OB
BIOMEDICAL TECHNIQUES AND TECHNOLOGIES
Main language of instruction: English

Other languages of instruction: Catalan, Spanish

Teaching staff


Make an appointment via email.


Introduction

Tissue Engineering (TE) is a discipline within Regenerative Medicine that applies the principles of engineering and life sciences to the development of biological substitutes that repair, maintain, or improve tissue function.


Objectives

• Learn the basics of TE

• Understand the different signaling processes and cell-material interactions

• Learn the different methods of making scaffolding for TE

• Understand and apply the principles of TE in the development of new devices for different target tissues.


Competences/Learning outcomes of the degree programme

• CB1 - That students have demonstrated that they possess and understand knowledge in an area of study that is based on general secondary education, and is usually found at a level that, while supported by advanced textbooks, includes also some aspects that involve knowledge coming from the vanguard of his field of study

• CB2 - That students know how to apply their knowledge to their work or vocation in a professional way and have the skills that are usually demonstrated through the development and defense of arguments and problem solving in their area of study

• CB4 - That students can convey information, ideas, problems and solutions to both specialized and non-specialized audiences

• CB5 - That students have developed those learning skills necessary to undertake further studies with a high degree of autonomy

• CE16 - Apply the terminology of Bioengineering both orally and in writing in a third language.

• CG10 - Know how to work in a multilingual and multidisciplinary environment

• CG3 - Have the ability to learn new methods and theories and be versatile to adapt to new situations.

• CG4 - Solve problems with initiative, decision making, creativity, critical and communication reasoning and transmission of knowledge, skills and abilities in the field of Bioengineering.


Learning outcomes of the subject

  • • Know the principles of TE.

  • • Know and implement the different mechanisms of cell signaling for the development of new therapies based on TE.

  • • Know the different methods for the manufacture of scaffolding for TE, with special emphasis on the properties of biomaterial, both biological and physicochemical.

  • • Know the limitations of TE in terms of vascularization of TE constructs and how to improve these limitations.

  • • Know and understand TE globally for the development of new TE strategies for different target tissues.

  • • Be able to interpret and reason the scientific bibliography.

  • • Know and put into practice the way and dynamics of teamwork

  • • Be able to develop in a scientific field.

Syllabus

1. Tissue Engineering: An introduction

2. Cell–Material Interactions 

3. Scaffold Design and Fabrication

4. Microfabrication Technology in Tissue Engineering

5. Extracellular Matrix as a Bioscaffold for Tissue Engineering

6. Vascularization, Survival, and Functionality of Tissue-Engineered Constructs


Teaching and learning activities

In person



The subject is divided into topics, so that the subject presents the basic concepts. The subject will be divided into theoretical and practical classes.

Les classes s’impartiran en anglès, tot i que els dubtes de l’alumnat es respondran en l’idioma que es prefereixi (castellà, català o anglès). However, the exercises, presentations and exams can only be done in English. The didactic material will be presented in English mainly, with some exceptions (graphs, tables ...).


Evaluation systems and criteria

In person



Exam 1st call:

1) Exercises: 20%

2) Lab work: 30%

4) Final exam: 50%

Exam 2nd call: will follow the same criteria as the previous one, but without the option of honors registration.

 

Important considerations:

1. Plagiarism, copying or any other action that may be considered cheating will be zero in this section of the evaluation. Doing so in the exams will mean the immediate suspension of the subject.

2. The minimum mark of the final exam to pass the subject must be higher than 4.5.

3. Changes to the calendar, exam dates or assessment system will not be accepted. Exchange students (Erasmus and others) or repeaters will be subject to the same conditions as the rest of the students.


Bibliography and resources

  • Clemens A. Van Blitterswijk and Jan De Boer, Tissue Engineering 2015, Elsevier, Amsterdam.

  • Buddy D. Ratner, Allan S. Hoffman, Frederick J. Schoen, Jack E. Lemons, Biomaterials

  • Science An Introduction to Materials in Medicine (2nd Edition), Elsevier, Amsterdam.

  • Articles científics (per determinar)

Evaluation period

E: exam date | R: revision date | 1: first session | 2: second session:
  • E1 12/01/2021 A08 16:00h