Universitat Internacional de Catalunya

Regenerative Medicine and Tissue Engineering

Regenerative Medicine and Tissue Engineering
3
13510
4
First semester
OB
BIOMEDICAL TECHNIQUES AND TECHNOLOGIES
Main language of instruction: English

Other languages of instruction: Catalan, Spanish

Teaching staff


Dr. MATEOS TIMONEDA, Miguel Angel - mamateos@uic.es

Make an appointment via email.


Introduction

Tissue Engineering (TE) is a discipline within Regenerative Medicine that applies the principles of engineering and life sciences to the development of biological substitutes that repair, maintain, or improve tissue function.


Objectives

• Learn the basics of TE

• Understand the different signaling processes and cell-material interactions

• Learn the different methods of making scaffolding for TE

• Understand and apply the principles of TE in the development of new devices for different target tissues.


Competences/Learning outcomes of the degree programme

CB1: That students have demonstrated to possess and understand knowledge in an area of study that starts from the base of general secondary education, and is usually found at a level that, although supported by advanced textbooks, also includes some aspects they involve knowledge coming from the forefront of their field of study.

CB3: That students have the ability to gather and interpret relevant data (normally within their area of study) to make judgments that include a reflection on relevant issues of a social, scientific or ethical nature.

CB4: That students can transmit information, ideas, problems and solutions to both a specialized and non-specialized audience

CG3: Use and critically assess biomedical techniques.

CG7: Integrate the basic concepts related to the field of biomedicine both at a theoretical and experimental level

CE16: Identify and know how to apply the instrumental and experimental techniques of the disciplines in the field of Biomedical Sciences, as well as the technology related to the biomedical, health and industrial field.

CT1: Develop the capacity for organization and planning appropriate to the moment.

CT2: Develop the ability to solve problems.

CT3: Develop the capacity for analysis and synthesis.

CT8: Reason and evaluate situations and results from a critical and constructive point of view.

CT10: Being able to carry out autonomous learning.

CT11: Apply theoretical knowledge to practice.

CT12: Apply the scientific method.

Learning outcomes of the subject

  • • Know the principles of TE.

  • • Know and implement the different mechanisms of cell signaling for the development of new therapies based on TE.

  • • Know the different methods for the manufacture of scaffolding for TE, with special emphasis on the properties of biomaterial, both biological and physicochemical.

  • • Know the limitations of TE in terms of vascularization of TE constructs and how to improve these limitations.

  • • Know and understand TE globally for the development of new TE strategies for different target tissues.

  • • Be able to interpret and reason the scientific bibliography.

  • • Know and put into practice the way and dynamics of teamwork

  • • Be able to develop in a scientific field.

Syllabus

1. Tissue Engineering: An introduction (1 session)

2. Biomaterials (3 sessions: concepts, characterization, degradation)

3. Scaffold Design and classical fabrication techniques (1 session)

4. 3D (Bio)printing in Tissue Engineering (1 session)

5. Cell-materials interactions (1 session)

6. Bioreactors in TE (1 session)

7. Vascularization, Survival, and FUNCTIONALITY of Tissue-Engineered constructs (1 session)

8. Organ on a chip (1 session)

Teaching and learning activities

In person



The subject is divided into topics, so that the subject presents the basic concepts. The subject will be divided into theoretical and practical classes.

Les classes s’impartiran en anglès, tot i que els dubtes de l’alumnat es respondran en l’idioma que es prefereixi (castellà, català o anglès). However, the exercises, presentations and exams can only be done in English. The didactic material will be presented in English mainly, with some exceptions (graphs, tables ...).


Evaluation systems and criteria

In person



Exam 1st call:

1) Exercises: 20%

2) Lab work: 30%

4) Final exam: 50%

Exam 2nd call: will follow the same criteria as the previous one, but without the option of honors registration.

 

Important considerations:

1. Plagiarism, copying or any other action that may be considered cheating will be zero in this section of the evaluation. Doing so in the exams will mean the immediate suspension of the subject.

2. The minimum mark of the final exam to pass the subject must be higher than 5.

3. Changes to the calendar, exam dates or assessment system will not be accepted. Exchange students (Erasmus and others) or repeaters will be subject to the same conditions as the rest of the students.


Bibliography and resources

  • Clemens A. Van Blitterswijk and Jan De Boer, Tissue Engineering 2015, Elsevier, Amsterdam.

  • Buddy D. Ratner, Allan S. Hoffman, Frederick J. Schoen, Jack E. Lemons, Biomaterials

  • Science An Introduction to Materials in Medicine (2nd Edition), Elsevier, Amsterdam.

  • Articles científics (per determinar)

Evaluation period

E: exam date | R: revision date | 1: first session | 2: second session:
  • E1 11/01/2023 A10 16:00h
  • E2 21/06/2023 A04 14:00h
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