Universitat Internacional de Catalunya
Pharmacology
Teaching staff
An appointment by e-mail
Dra. Rosalía Rodríguez: rrodriguez@uic.es
Dra. Mireia Andrés: mandres@uic.es
Dra. Núria Casals: ncasals@uic.es
Dra. Ana Paula Dantas: adantas@uic.esadantas@uic.es
Dra. Ariadna Tibau: atibau@uic.es Dra. Estel Curado: estelcurado@uic.es Dra. Cristina Salnias: csalinas@uic.es Dr. Albert Pantaleoni: apantaleoni@uic.es Dra. Helena Muley: helenamuley@uic.es
Introduction
Pharmacology is one of the cornerstones of medical practice. The provider must know in detail the different groups of drugs, their mechanism of action, pharmacokinetics, indications, various types of adverse reactions and contraindications, etc. You should also be prepared to make the most appropriate medication prescription for each patient, taking into account the physicochemical characteristics of the individual pathological, drug interactions, medical ethics and the rational use of medicines.
Pre-course requirements
Basic knowledge of anatomy, physiology, biochemistry and molecular biology
Objectives
To present the main groups of drugs and medicines representative of each group, their indications, mechanism of action, adverse reactions and contraindications.
To present the main routes of drug administration and the processes of absorption, metabolism, distribution and elimination, as well as existing tools for study.
Highlight the main types of drug interactions
Show the students the different physiological and pathological situations that modulate the effects of drugs
To demonstrate the usefulness and management of major drug databases.
To familiarize students with reading and critical understanding of scientific articles in pharmacology.
Competences/Learning outcomes of the degree programme
Understanding the basics of action, indications and efficacy of pharmacological interventions based on scientific evidence
Ability to prescribe appropriate drugs to the patient
Learn to identify adverse drug reactions and drug interactions
Knowing how to use the databases available drugs
Ability to work in group
Self-learning ability
Ability to integrate knowledge to solve a medical problem
Learning outcomes of the subject
At the end of the course the student will be able to:
- Identify the main groups of drugs, their indications, mechanism of action, pharmacokinetics, dosage, adverse reactions and contraindications
- Know and use the most important drugs for the treatment of specific diseases of the nervous system, cardiovascular system, blood system, renal system, respiratory, digestive and endocrine system.
- Know and use the most relevant drugs to treat pain, inflammation, allergic reactions, immune system disorders and cancer.
- Know how to use drugs for the treatment of bacterial, viral, fungal and parasitic
- Know how to properly use the search engines to information and databases on drugs
- Know how to identify drug interactions and adverse reactions of the drugs with concomitant use of several drugs in the same patient and suggest changes to avoid drug treatment.
Syllabus
Module 1. General Pharmacology
1. Introduction to pharmacology: concepts, objectives, its role in medicine. Mechanism of drug action (pharmacodynamics)
2. Pharmacokinetics: absorption, distribution, metabolism and elimination of drugs. Pharmaceutical forms and routes of administration.
3. Toxicity and adverse drug reactions. Drug Interactions. Dosage in various physiological and pathological conditions. The clinical trial.
Module 2: Pharmacology of peripheral nervous system
4. Neurotransmitters and receptors of the autonomic system. Sympathetic nervous system drugs
5. Parasympathetic nervous system drugs. Neuromuscular blocking and ganglion.
Module 3: Central Nervous System Pharmacology
6. Types of pain. Scale pain therapy. Opioid analgesics. Treatment of chronic pain.
7. Anticonvulsivant drugs. Treatment of neurodegeneratives diseases: Alzeheimer and Parkinson.
8. Psychopharmacology: anxiolytics-hypnotics, antidepressants, antipsychotics and mood stabilizers.
Module 4: Anesthesia
9. General and local anesthetics
Module 5: Pharmacology of pain and inflammation
10. Steroidal anti-inflammatory. Analgesics and anti-inflammatory drugs (NSAIDs). Rheumatism modulating drugs. Antihistamines. Treatment of gout.
Module 6: Pharmacology of infectious processes
11. Antibacterial drugs
12. Antivirals
13. Antifungal, antiparasitic drugs, anthelmintic and antiprotozoal.
Module 7: Pharmacology of cardiovascular system
14. Diuretics and antihypertensive drugs
15. Digitalis glycosides. Antianginal drugs. Antiarrhythmic drugs.
16. Pharmacology of thrombosis: anticoagulants, antiplatelet and fibrinolytic drugs. Fibrinolysis inhibitors.
17. Hypolipidemic drugs. Drugs for treatment of obesity.
18. Antianemics
Module 8: Pharmacology of the respiratory system
19. Bronchodilators and anti-asthmatic drugs, antitussives, mucolytic drugs and expectorants.
Module 9: Pharmacology of the digestive
20. Antiulcer, gastrokinetic, antiemetics, laxatives and antidiarrheal.
Module 10: Endocrine Pharmacology
21. Diabetes Treatment
22. Pituitary hormones. Treatment of hypo and hyperthyroidism.
23. Sex hormones and hormonal contraceptives
24. Osteoporosis Treatment
Module 11: Chemotherapy and immunosuppressive
25. Immunosuppressive drugs
26. Cancer chemotherapy
Teaching and learning activities
In person
- Lectures
- Virtual activities: teaching material or activities available in Moodle.
- Case method: Students, in groups, solve clinical cases that will be provided the same day of the class. In the classroom the students present their findings with the active participation of the teacher.
- Laboratory practice: Students use molecular and cellular biology techniques to study the mechanism of action of drugs. Students work in the lab under the supervision of the professor.
Evaluation systems and criteria
In person
1st call
Resolution of cases, written assignments, online activities and class participation (online/on-site): 20% of the final grade. Assistance to at least 80% of clinical cases. This mark includes the participation/assistance to the practical sessions in the lab (mandatory).
Midterm exam: 20% of the final grade
Final exam: 60% of the final grade (requires at least a grade of 5 in the final examination to approve the subject)
The content of cases or other activities are subject of examination.
2nd call
Final exam. The content of cases or other activities are subject of examination.
Other calls
Not required to repeat the practical lessons or attend lectures or case resolution. The repeater student who wants to attend practices or / and cases should inform the professor of the course
If the student does not attend to the theoretical or practical classes, the grade of the subject will be the mark obtained in the final exam
Bibliography and resources
Books
- P.Lorenzo, A. Moreno, J.C. Leza, I. Lizasoain, M.A. Moro. “Velazquez, Farmacología básica y clínica”. Ed. Panamericana
- H.P. Rang, M.M. Dale. “Farmacología”. Ed. Elsevier-España.
- J. Florez. “Farmacología humana”. Ed. Masson
On-line resources:
- aemp.es
- vademecum.es
Evaluation period
- E1 16/01/2023 14:00h