Subject

Micro and Nanotechnology

  • code 13549
  • course 3
  • term Semester 1
  • type op
  • credits 6

Module: ELECTIVE

Matter: ELECTIVE

Main language of instruction: English

Other languages of instruction: Catalan, Spanish,

Timetable
 Sem.1  TU 14:00 16:00 P2A03
 Sem.1  FR 16:00 18:00 P2A03

Teaching staff

Head instructor

Dr. Emilio CASTRO - ecastro@uic.es

Office hours

Hours agreed with the teacher at the beginning of the academic year. In any case, you can make an appointment and arrange a face-to-face tutoring with the teacher by writing to the email ecastro@uic.es.

Introduction

In the event that the health authorities announce a new period of confinement due to the evolution of the health crisis caused by COVID-19, the teaching staff will promptly communicate how this may effect the teaching methodologies and activities as well as the assessment.

Countless healthcare and biomedical solutions with high impact in terms of timely diagnostics, therapeutic success, patient comfort or financial sustainability of healthcare systems rely on micro- and nanotechnologies. Thus, it is not at all exaggerate to claim that such technologies play in current days a tremendous role with respect to improving the quality of our life, health and well-being, which are the main priorities of modern science. Harmonically combining biomaterials, cells and biologically relevant molecules to generate in vitro structures that mimic tissue for the proper development of regenerative medicine and tissue engineering, requires the use of micro-level manufacturing techniques and the use of nanometric materials to be able to condition not only the chemical and physical properties at the micrometer scale, but also adapt the cell interactions to this sub-micrometric level.

Pre-course requirements

Subjects: Materials, Biomaterials and biocompatibility, Advanced materials and selection of materials, Shaping techniques of materials.

Objectives

  • Know the fundamentals of micro and nanotechnologies and their application to the design and development of chemical sensors, biosensors and microchips.
  • Understand the principles, design and cutting-edge applications for analysis and detection based on micro and nanotechnologies.
  • Understand the principles and applications of advanced characterization techniques of chemical systems consisting of nanomaterials of high current interest.

Competences / Learning outcomes of the degree programme

  • CB2 - Students must know how to apply their knowledge to their work or vocation in a professional way and have the competences that are demonstrated through the creation and defence of arguments and the resolution of problems within their field of study.
  • CB4 - Students can transmit information, ideas, problems and solutions to specialist and non-specialist audiences.
  • CG10 - To know how to work in a multilingual and multidisciplinary environment.
  • CG4 - To resolve problems based on initiative, be good at decision-making, creativity, critical reasoning and communication, as well as the transmission of knowledge, skills and prowess in the field of Bioengineering
  • CT5 - To use information sources in a reliable manner. To manage the acquisition, structuring, analysis and visualisation of data and information in your specialist area and critically evaluate the results of this management.
  • CT7 - To be fluent in a third language, usually English, with a suitable verbal and written level that is in line with graduate requirements.
  • CE17 - To be able to identify the engineering concepts that can be applied in the fields of biology and health.
  • CE18 - To define the main principles of the technologies that are used for the design and manufacture of micro and nano-sensors in biotechnological areas.

Learning outcomes of the subject

Upon completion of this subject, students will be able to:

  • Know and understand the scientific foundations on which nanotechnology is based.
  • Understand the conceptual and methodological foundations of the micro and nanotechnologies that form bioengineering.
  • Develop the ability to perform a work autonomously by searching for useful sources of information and discuss them.
  • Present orally in public technical information.

Syllabus


Chapter 1 Introduction to micro and nanotechnologies.
      1.1 Introduction and historical review of micro and nanotechnology. Feynman's vision.
      1.2 Emerging technologies. Nanotechnology Market. Technological revolution.
      1.3 Nanomaterials: Classification and applications. Properties dependent on size.
      1.4 Characteristic quantum phenomena. Electron confinement.
      1.5 Current state of the art. Nanotechnology applications: Nanoelectronics, Nanorobotics, Nanobiotechnology.

Chapter 2 Miniaturization and nanometric scale.
      2.1 The micro and nanoscale.
      2.2 Beyond Moore's law.
      2.3 Scaling laws.
      2.4 Nanomaterials. Properties dependent on size.
      2.5 Nanotechnology applications: Nanoelectronics, Nanorobotics, Nanobiotechnology.

Chapter 3 Definition, need, application of micro and nanotechnologies in bioengineering.
      3.1 Definition of nanotechnology (EU versus USA).
      3.2 Definition of nanomedicine.
      3.3 Definition of nanomaterial – Size distributions.
      3.4 Need of bioengineering nanotechnology.
      3.5 Benefits of micro and nanotechnologies in tissue engineering.

Chapter 4 Micro and nanomaterials used in bioengineering.
      4.1 Nanomaterials.
      4.2 Nanoscaffolds.
      4.3 Clinical nanoparticles.

Chapter 5 Introduction to micro and nanomaterial characterization techniques.
      5.1 Microscopy.
      5.2 Diffraction.
      5.3 Spectroscopy.

Chapter 6 Lithographic processes.
      6.1 Photolithography.
      6.2 Immersion lithography.
      6.3 Nanoimprint lithography.
      6.4 Dip-Pen Nanolithography.

Chapter 7 Thin film deposits.
      7.1 Physical: Sputtering.
      7.2 Chemical: Chemical Vapor Deposition.
      7.3 Wet: Spin coating.

Chapter 8 Microfluidic technology.

Chapter 9 Production of nanoparticles and their applications.
      9.1 Ag NPs.
      9.2 MNPs.
      9.3 Industrial applications of NPs.

Chapter 10 Design and manufacture of micro and nanosensors.
      10.1 Definition of nanosensors.
      10.2 Manufacture methods.
      10.3 Types of nanosensors.
      10.4 Nanostructures and nanomaterials.
      10.5 Applications.

Teaching and learning activities

In person

During the face-to-face classes, the fundamental aspects of each topic will be exposed so that they can be developed individually by each student through the use of selected bibliography and with the support of tutorials. Innovative educational methodologies such as Peer instruction, Flipped Classroom, LegoTM Serious Play will be followed in the course.

During the course, students will be asked to complete the following training activities:

Peer Instruction - Short questions thrown by the teacher at the beginning or end of the virtual or face-to-face class on the subject being treated in the subject at that time to which students must answer individually through a forum of Question and Answer (Q&A) evaluable enabled for it in Moodle, in such a way that among the students cooperatively construct the correct answer to the short question (which may fall in the examination of the subject) - the teacher will indicate the answers of those students That they are correct and this will allow them to score points for the evaluation of active participation.

Modelling (Do it yourself - DIY) - Construction of models and models in a group, during a practical seminar-type classroom, allowing students to learn by doing (such as a carbon fullerene / nanotube model or atomic force microscope model with Lego bricks) in a Lego Serious Play type learning methodology. Once the model or model has been built, students will be asked to use that model or model to carry out an activity that allows them to deepen their knowledge of the technology, technique or modelled material following a script provided by the teacher.

Treasure Hunt (Reading Promotion) - Divide the classroom into two groups, each with a spokesperson who goes to the library to look for a book indicated by the teacher (different for each group), in such a way that each one of the groups, look for a series of data or explanations requested by the teacher in the indicated book and cooperatively build a document with those data and explanations taken from the book and to be delivered, through the spokesperson, via the Moodle task, to the teacher at the end of class. The teacher will give points of active participation in the evaluation of the subject to the group that does it best.

Flipped Classroom - The teacher will post a link to a YouTube video in the Moodle about some aspect of the subject's syllabus that the students will visualize either as homework before the corresponding non-face-to-face class or during the break of the face-to-face class projecting it on the class screen. After viewing the video, the teacher will propose to the students to take a quiz through a tool like Socrative or Kahoot using their mobile phones, tablets or computers to check the assimilation of the concepts covered in the video. The teacher will give active participation points in the subject to students who answer correctly and more quickly to the quiz questions.

Laboratory practices - Learning based on small research projects in which they individually develop the script of the proposed practices themselves from a basic bibliography of consultation and a list of equipment available in the laboratory of degree practices, work cooperatively to obtain experimentally in the grade practice laboratory, some nanoparticles or a microfluidic device and present / explain to the rest of their classmates and the teacher their work procedure, materials used and results obtained as a research seminar.

Evaluation systems and criteria

In person

The structure of the subject in theoretical and practical sessions involves the evaluation of the knowledge and skills acquired in a differentiated and complementary manner. In the case of the contents of the theoretical sessions, they will be evaluated in a partial and in a final test, both written and that will take into account both the ability to relate the contents of the different topics in a transversal way, as well as the development of one´s own thinking. Regarding the practical part of the subject, the evaluation will be continue, considering the following aspects with different relative weight: active participation in class, final course work and peer evaluation, laboratory practices, debate after the reading of the complementary bibliography. In order for both parts of the subject to be able to average and thus obtain the final grade for the subject, it will be necessary for both parts of the subject to be passed independently.

 

The student´s qualification will be:

 

 

1st call

 

Assessment type

Evaluation system

Weighing

Summative evaluation

Final exam

35 %

Summative evaluation

Midterm exam

25 %

Formative assessment

Oral presentation – research seminar

15 %

Diagnostic evaluation

Self-assessment test

0 %

Authentic evaluation

Laboratory practices

15 %

Active participation

Peer instruction

Flipped classes

Modelling

Treasure hunt

10 %

   

2nd call

 

 

Assessment type

Evaluation system

Weighing

Summative evaluation

Final exam

70 %

Formative assessment

Oral presentation – research seminar

15 %

Diagnostic evaluation

Self-assessment test

0 %

Authentic evaluation

Laboratory practices

15 %

 

 

 

Important considerations:

  1. Plagiarism, copying or any other action that may be considered cheating will be zero in that evaluation section. Besides, plagiarism during exams will mean the immediate failing of the whole subject.
  2. In the second-sitting exams, the maximum grade students will be able to obtain is "Excellent" (grade with honors distinction will not be posible).
  3. Changes of the calendar, exam dates or the evaluation system will not be accepted.
  4. Exchange students (Erasmus and others) or repeaters will be subjected to the same conditions as the rest of the students.

Bibliography and resources

(1). Rogers, B., Adams, J., Pennathur, S. (2017). Nanotechnology: understanding small systems. CRC Press.

(2). Mendelson. M. I. (2018). Learning Bio-Micro-Nanotechnology. CRC Press.

(3). Abdullaeva, Z. (2017). Nano- and Biomaterials: Compounds, Properties, Characterization, and Applications. Wiley-VCH Verlag.

(4). Bhushan, B. (2017). Handbook of nanotechnology. Springer.

(5). Poole Jr., C. P., Owens. F.J. (2003). Introduction to Nanotechnology. Wiley-Interscience.

During the course, innovative articles and reviews on specific aspects discussed in it will appear in scientific journals and we will discuss some of them.

Evaluation period

E: exam date | R: revision date | 1: first session | 2: second session:

  • E1 15/01/2021 16:00h P2A03
  • E2 30/06/2021 16:00h P2A02
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