Subject

Fundamentals of Physiopathology

  • code 13551
  • course 3
  • term Semester 2
  • type op
  • credits 6

Module: ELECTIVE

Matter: ELECTIVE

Main language of instruction: Catalan

Other languages of instruction: English, Spanish

Timetable
group M
 Sem.2  MO 18:00 20:00 P2A03
 Sem.2  TU 18:00 20:00 P2A01

Teaching staff

Head instructor

Dr. Mariano FERNÁNDEZ - RODRIGUEZ - mfernandezfa@uic.es

Office hours

Dr. Mariano Fernández Fairen mfernandezfa@uic.es

Introduction

Is a basic discipline in all Sciences that are dedicated directly to or collaterally to healthcare. It emerges from the convergence between physiology and pathology. Physiology is the branch of biology which studies the processes and mechanisms that operate within an organism. Pathology is the part of medicine that has as objective the description of the observable conditions during a diseased state. 

It is dedicated to the study of biological, biochemical, genetical, immune phenomena amongst others, that take place at organic, tissue, cellular and molecular levels and their alterations and mechanisms of which different diseased originate. This permits the explanation of the origin and importance of the noxa, why symptoms occur and the diversity of manifestations that accompany it, as well as the possible ways of correction and compensation of these alterations. 

It is a fundamental discipline for all bioengineers because they need to know and understand everything mentioned above for a proper approximation to problems concerning these pathologies and effort to resolve them. 

Pre-course requirements

Must have passed the course of the first year such as Anatomy and Physiology, Chemistry/Biochemistry and Cellular and Molecular Biology. And the courses of the second year such as Applied Physiopathology and Cellular and Molecular Biology 2.

 

Objectives

  • Know and understand the pathophysiological process throughout the life cycle, identifying the problems and preventive and clinical aspects of the person, both in health as in disease.
  • Acquire the medical knowledge referred to the healthy or sick human being at all phases of their life cycle, from childhood to old age, that enable them to evaluate, synthesize and apply the resources and solutions provided by Bioengineering to these situations.
  • Synthesis of the contents: To understand well and in depth why and how the functions and mechanisms of living beings are altered, it is necessary to know the physical, chemical and biological principles of these processes by combining approximations at atomic, molecular, cellular, genetic and immunological levels.

Competences / Learning outcomes of the degree programme

  • CB1 - Students must demonstrate that they have and understand knowledge in an area of study based on general secondary education. This knowledge should be of a level that, although based on advanced textbooks, also includes some of the cutting-edge elements from their field of study.
  • CB2 - Students must know how to apply their knowledge to their work or vocation in a professional way and have the competences that are demonstrated through the creation and defence of arguments and the resolution of problems within their field of study.
  • CB3 - Students must have the ability to bring together and interpret significant data (normally within their area of study) and to issue judgements that include a reflection on important issues that are social, scientific or ethical in nature.
  • CB4 - Students can transmit information, ideas, problems and solutions to specialist and non-specialist audiences.
  • CB5 - Students have developed the necessary learning skills to undertake subsequent studies with a high degree of autonomy.
  • CE15 - The ability to undertake a project through the use of data sources, the application of methodologies, research techniques and tools specific to Bioengineering, give a presentation and publicly defend it to a specialist audience in a way that demonstrates the acquisition of the competences and knowledge that are specific to this degree programme.
  • CE16 - To apply specific Bioengineering terminology both verbally and in writing in a foreign language.
  • CE17 - To be able to identify the engineering concepts that can be applied in the fields of biology and health.
  • CE8 - To hold a dialogue based on critical thinking on ideas connected to the main dimensions of the human being
  • CG10 - To know how to work in a multilingual and multidisciplinary environment.
  • CG2 - To promote the values that are specific to a peaceful culture, thus contributing to democratic coexistence, respect for human rights and fundamental principles such as equality and non-discrimination.
  • CG3 - To be able to learn new methods and theories and be versatile so as to adapt to new situations.
  • CG4 - To resolve problems based on initiative, be good at decision-making, creativity, critical reasoning and communication, as well as the transmission of knowledge, skills and prowess in the field of Bioengineering
  • CG7 - To analyse and evaluate the social and environmental impact of technical solutions
  • CG8 - To apply quality principles and methods.
  • CT2 - The ability to link welfare with globalisation and sustainability; to acquire the ability to use skills, technology, the economy and sustainability in a balanced and compatible manner.
  • CT3 - To know how to communicate learning results to other people both verbally and in writing, and well as thought processes and decision-making; to participate in debates in each particular specialist areas.
  • CT4 - To be able to work as a member of an interdisciplinary team, whether as a member or by management tasks, with the aim of contributing to undertaking projects based on pragmatism and a feeling of responsibility, taking on commitment while bearing the resources available in mind.
  • CT5 - To use information sources in a reliable manner. To manage the acquisition, structuring, analysis and visualisation of data and information in your specialist area and critically evaluate the results of this management.
  • CT6 - To detect gaps in your own knowledge and overcome this through critical reflection and choosing better actions to broaden your knowledge.
  • CT7 - To be fluent in a third language, usually English, with a suitable verbal and written level that is in line with graduate requirements.

Learning outcomes of the subject

  • Know the function of the organism, tissues and cells of the human body and health
  • Know the genetical biochemical, metabolical immune, trauma, infectious and environmental reasons of disorders that compromise health
  • Know the molecular, celular and tissue mechanims in pathology
  • Know the organic, tissue, celular and molecular alteration at the base of a pathology
  • Known the molecular, tissue and celular mechanisms of a pathology
  • Known the manifestations or simptoms of a pathology
  • Know and assess the compementary means for a diagnostic
  • Know and assess the therapeutic means and possible solutions of the organic alterations. 
  • Reason the principles and bases concerning Bioengineering and reason and function of all this knowledge

Syllabus

Program:

1.- Biology

2.- Biochemistry

3.- The cell

4.- The metabolism

5.- Cellular reproduction

6.- Cell death

7.- Microbiota and microbiome

8.- The tissues

9.- Organs and Systems

10.- Genetics

11.- Nutrition

12.- Metabolic syndrome

13.- Immunity

14.- Inflammation

15.- Infection

16.- Shock

17.- Multiorgan dysfunction syndrome

18.- Sensory disorders

19.- Pain

20.- Motor disorders

21.- Cancer

22.- Involution

23.- The environment

Teaching and learning activities

In person

Exposition: Transmit knowledge and activate cognitive processes of the student, implicating his participation via lectures of every theme. 

Cooperative learning: Developing active learning via cooperative assignments between students and fomenting shared responsibility to reach team goals. 

Learning activities based on problems (Problem Based Learning): 

  • Based on the enouncement, analysis, processing and solution of real problems
  • Promote responsibility in the student about their own learning process
  • Development of a relevant base of knowledge
  • Development of abilities to critically evaluate and the acquisition of new knowledge
  • Development of abilities to pose complex problems and possible solutions
  • Development of abilities to have interpersonal relationships
  • Involving the student to increase his initiaive and enthusiasm
  • Development of cognitive, integrating and communicative expression abilities

Evaluation systems and criteria

In person

Will be considered at 50%

a) Written work on a subject chosen by the student

b) Oral exam about the program

 

Important considerations:

  1. Plagiarism, copying or any other action that may be considered cheating will be zero in that evaluation section. Besides, plagiarism during exams will mean the immediate failing of the whole subject.
  2. In the second-sitting exams, the maximum grade students will be able to obtain is "Excellent" (grade with honors distinction will not be posible).
  3. Changes of the calendar, exam dates or the evaluation system will not be accepted.
  4. Exchange students (Erasmus and others) or repeaters will be subjected to the same conditions as the rest of the students.

Bibliography and resources

Bibliographic resources of images and videos are on the course webpage

Complementary bibliography: 

  • Verbruggen SW: Mechanobiology in Health and Disease. Academic Press, Elsevier, 2018.
  • Copstead-Kirkhorn LE, Banasik JL: Pathophysiology. Elsevier, 2014.

Evaluation period

E: exam date | R: revision date | 1: first session | 2: second session:

  • E1 25/05/2020 18:00h
  • E2 22/06/2020 16:00h
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