Subject

Molecular and Cellular Physiology Applied to Physiotherapy

  • code 07844
  • course 1
  • term Semester 2
  • type FB
  • credits 6

Module: Basic training

Matter: Physiopathology I

Main language of instruction: Spanish

Other languages of instruction: English

Timetable
 Sem.2  TU 10:00 12:00 
 Sem.2  FR 08:00 10:00 

Teaching staff

Head instructor

Dr. Samuel BRU - sbru@uic.es

Office hours

Contact: sbru@uic.es

Introduction

Nowadays, illness are explained on molecular terms, and the knowledge of Biochemistry and Cell Biology is indispensable for performing a correct analysis of the etiology, diagnosis, therapeutics and evaluation of the therapeutic processes. This is why the future professionals of medicine must know how the human body works on biochemical and molecular basis.

The subject tries to give to the student of medicine a global view about the basic aspects of Biochemistry, Cell Biology and about the scientific methodology in general. The subject is made on a practical way, trying to focus in each topic those concepts and situations that adapts better to the comprehension associated to the professional exercice in the field of Physiotherapy.

Pre-course requirements

The subject, do not require any specific administrative condition. Despite this, in order to develop the course successfully, you should have the following knowledge:

- Knowledge of Physics, Chemistry, Biochemistry, Molecular and Cell Biology of second high school level.

Objectives

The main objective of this course is that students acquire the skills described below. Moreover it is also intended to familiarize students with the scientific method and get them used to reasoning and discussion of problems under a biological point of view. The third objective is to facilitate the theoretical base to understand the following clinical subjects.

Competences / Learning outcomes of the degree programme

The physiotherapy student, at the end of the course, should have improved their ability to:

1) Understand the key molecular mechanisms that govern the physiology and pathology of the human body, with special reference to those related to the field of Physiotherapy.
2) Assess research as a key element in modern medicine.

3) Be curious about the world around and want to learn more.

  • 10 - Develop autonomous learning skills.
  • 16 - Demonstrate a sensitivity towards environmental issues.
  • 17 - The ability to work responsibly and autonomously, so as to handle job-related activities without the need for strict supervision.
  • 21 - Knowledge of the physiological and structural changes that can occur after physiotherapeutic interventions.
  • 24 - Knowledge of the physical bases of the various physical interventions and their applications in physiotherapy.
  • 29.1 - Demonstrate a committment to ongoing learning and self-improvement.
  • 39 - Knowledge of general aspects of exogenous and endogenous diseases related to physiotherapy for all the biological systems and the corresponding medical, surgical, orthopedic and physiotherapy treatments.
  • 40 - Knowledge about, physiological, functional and behavioral changes that occur after physiotherapeutic intervention.

Learning outcomes of the subject

At the end of the course, the student: - Knows the structure and function of biomolecules.  - Applies the principles of inorganic chemistry and organic chemistry in the study of biomolecules and fundamental biochemical processes.  - Knows the structure and composition of cells.  - Knows the main metabolic routes.  - Understands and integrates metabolic regulation systems.  - Is curious about what is considered normal and knows how to formulate questions and hypotheses. 

Syllabus


Chapter 1 Introduction

Chapter 2 Mineral components of human body

Chapter 3 Glucides Estructure and Function

Chapter 4 Lipids Estructure and Function

Chapter 5 Protein Estructure and Function

Chapter 6 Nucleic Acids Estructure and Function

Chapter 7 HUman Cell Estructurae and Function

Chapter 8 The Muscle Cell

Chapter 9 Introduction tot he Human Genome

Chapter 10 Control of the gene expresion

Chapter 11 Introduction to the Genetics

Chapter 12 Cell Division and Death

Chapter 13 Introdution to the metabolism.

Chapter 14 Sugar and Lipid Metabolism

Chapter 15 Protein Metabolism

Chapter 16 Integration of Metabolism

Chapter 17 Cholesterol metabolism and other special lipids

Chapter 18 Iron Metabolism

Chapter 19 Nucleotid Metabolism

Chapter 20 Introduction to the Microbiology

Chapter 21 Introduction to the Inmunology

Teaching and learning activities

In person

Teaching strategies that will be used are as follows: 


1) Lectures: 50 minute presentation on a theoretical issue in which the professor mixes problem solving with practical case studies.
2) Clinical Cases: approaches to situations in relation to specific topics in the syllabus. Individual discussion in reduced and collective groups (the latter led by the teacher), and drawing conclusions.
3) Laboratory practice

TRAINING ACTIVITYMETHODOLOGYCOMPETENCESECTS CREDITS
self-learning activities
lectures
student's independant work-study
exterenal practical
apprenticeship contract
oral presentation / master class
case method
problem-solving exercises
10 16 17 21 24 29.1 39 40 6

Evaluation systems and criteria

In person

- 1st call

  • 1st partial examination
    • Flexible date, that will be defined according to theorical content timming.
    • 25 multiple choice questions with 4 possible answers, only 1 valid answer per question and counting +1 for correct answers and -0.25 will be deducted for each mistake.
    • From leson 1 to 9 (9 included).
    • 40% of the final grade.
    • Only scores of 5 and above will be considered for average calculation.
    • Scores of 5 and above will be kept for 2nd call.
  • 2nd partial examination
    • Will take place the day of the final exam.
    • 25 multiple choice questions with 4 possible answers, only 1 valid answer per question and counting +1 for correct answers and -0.25 will be deducted for each mistake.
    • From leson 10 to 18 (18 included).
    • 40% of the final grade.
    • Only scores of 5 and above will be considered for average calculation.
    • Scores of 5 and above will be kept for 2nd call.
  • Class attendance and participation
    • 10% of the final grade.
    • Class attendance and participation will be evaluated.
    • As it is inculded in the continued evaluation, there is no minimun score to be considered in average calculation.
    • Scores will be kept for 2nd call.
  • Metabolism academic work
    • 10% of the final grade.
    • Students must attend to two theorical sesions to opt for this grade percentage and class attendance and participation will be also evaluated toghether with work quality.
    • As it is inculded in the continued evaluation, there is no minimun score to be considered in average calculation.
    • Scores will be kept for 2nd call.

- 2nd call

  • If score from a test corresponding previous call is under five (1st partial and/or second partial), students will need to examinate again.
  • 25 multiple choice questions with 4 possible answers, only 1 valid answer per question and counting +1 for correct answers and -0.25 will be deducted for each mistake.
  • 40% of the final grade each partial.
  • 2nd call final grade will be used for average calculation toghether with continued evaluation score.
  • Students would not examinate again if previous score was five or above.
  • Scoring five or above in the first call means that students can not examinate the same part in the second call

- The assessment system for students who have taken 2 or more resits

  • Same considerations as 1st call.

- General points to consider on the evaluation system of the exam

  • 20% of the test questions may be concepts that were not discussed in the classroom, but are in the recommended bibliography.
  • Class participation means the contribution of interesting ideas or the approach to relevant issues, which help improve the quality of the teaching session, whether it being in a lecture or clinical case report. In this case, the mark for participation in class will be from 1 to 10 for those who actively participate; and, if appropriate, from -1 to -10 for students with inadequate behavior that harms the quality of the class session.
  • Exams will be multiple-choice tests with 4 response options, counting +1 for correct answers and -0.25 will be deducted for each mistake.
  • According to the development role of the professor in the classroom, the professor can decide to change the parameters of evaluation.

Bibliography and resources

- FREEMAN. Biología. Ed. Addison-Wesley. 

- LOZANO. Bioquímica para las ciencias de la vida. Ed. Reverté, 2000

- HARVEY. Bioquímica (5a ed), Wolters Kluwer.

- LODISH. Biologia Celular y Molecular (5a ed), Ed. Panamericana.

- MCKEE. Bioquímica. Las bases moleculares de la vida. MC Graw Hill.

- DEVLIN. Bioquímica. Ed. Reverté.

STRYER. Bioquímica I i II (6a ed). Ed. Reverté.

- LENHINGER. Principios de Bioquímica. Ed. Reverté.

- ALBERTS. Biología Molecular de la Célula, Ed. Omega.

Evaluation period

E: exam date | R: revision date | 1: first session | 2: second session:

  • E1 24/05/2019 08:00h
  • E2 05/07/2019 08:00h A01

Teaching and learning material

      Material
            Ppoint ppoin_cc_transduccio_de_senyals.pdf 
            Ppoint tema_8_la_cel.lula_muscular.pdf 
            Ppoint tema_10_control_de_la_expresion_genica.pdf 
            Ppoint tema_13_introduccio_al_metabolisme.pdf 
            Ppoint tema_14_catabolisme_de_sucres_i_lipids.pdf 
            Ppoint tema_15_metabolismo_de_las_proteinas.pdf 
            Ppoint tema_18_metabolisme_del_ferro.pdf 
            Ppoint tema_19_metabolisme_dels_nucleotids.pdf 
            Ppoint tema_12_reproduccion_y_muerte_celular.pdf 
            Ppoint tema_20_introduccio_a_la_microbiologia.pdf 
            Ppoint ppoin_cc_transduccio_de_senyals.pdf 
            Ppoint tema_19_metabolisme_dels_nucleotids.pdf 
            Ppoint tema_10_control_de_la_expresion_genica.pdf 
            Ppoint tema_13_introduccio_al_metabolisme.pdf 
            Ppoint tema_14_catabolisme_de_sucres_i_lipids.pdf 
            Ppoint tema_16_integracio_del_metabolisme.pdf 
            Ppoint tema_17_metabolisme_del_colesterol_i_lipids_especials.pdf 
            Ppoint tema_8_la_cel.lula_muscular.pdf 
            Ppoint tema_9_introduccion_al_genoma_humano.pdf 
            Ppoint ppoin_cc_transduccio_de_senyals.pdf 
            Ppoint tema_19_metabolisme_dels_nucleotids.pdf 
            Ppoint tema_11_introduccio_a_la_genetica.pdf 
            Ppoint tema_12_reproduccion_y_muerte_celular.pdf 
            Ppoint tema_20_introduccio_a_la_microbiologia.pdf 
            Ppoint tema_10_control_de_la_expresion_genica.pdf 
            Ppoint tema_13_introduccio_al_metabolisme.pdf 
            Ppoint ppoin_cc_transduccio_de_senyals.pdf 
            Ppoint tema_20_introduccio_a_la_microbiologia.pdf 
            Ppoint tema_9_introduccion_al_genoma_humano.pdf 
            Ppoint tema_14_catabolisme_de_sucres_i_lipids.pdf 
            Ppoint tema_15_metabolismo_de_las_proteinas.pdf 
            Ppoint tema_16_integracio_del_metabolisme.pdf 
            Ppoint tema_17_metabolisme_del_colesterol_i_lipids_especials.pdf 
            Ppoint tema_18_metabolisme_del_ferro.pdf 
            Ppoint tema_19_metabolisme_dels_nucleotids.pdf 
            Ppoint tema_11_introduccio_a_la_genetica.pdf 
            Ppoint tema_12_reproduccion_y_muerte_celular.pdf 
            Ppoint tema_15_metabolismo_de_las_proteinas.pdf 
            Ppoint tema_18_metabolisme_del_ferro.pdf 
            Ppoint tema_11_introduccio_a_la_genetica.pdf 
            Ppoint tema_9_introduccion_al_genoma_humano.pdf 
            Ppoint tema_7_estructura_y_funcion_de_la_celula_humana.pdf 
            Ppoint tema_14_catabolisme_de_sucres_i_lipids.pdf 
            Ppoint tema_8_la_cel.lula_muscular.pdf 
            Ppoint tema_20_introduccio_a_la_microbiologia.pdf 
            Ppoint tema_8_la_cel.lula_muscular.pdf 
            Ppoint tema_10_control_de_la_expresion_genica.pdf 
            Ppoint tema_13_introduccio_al_metabolisme.pdf 
            Ppoint tema_14_catabolisme_de_sucres_i_lipids.pdf 
            Ppoint tema_15_metabolismo_de_las_proteinas.pdf 
            Ppoint tema_18_metabolisme_del_ferro.pdf 
            Ppoint tema_19_metabolisme_dels_nucleotids.pdf 
            Ppoint tema_12_reproduccion_y_muerte_celular.pdf 
            Ppoint tema_20_introduccio_a_la_microbiologia.pdf 
            Ppoint ppoin_cc_transduccio_de_senyals.pdf 
            Ppoint tema_10_control_de_la_expresion_genica.pdf 
            Ppoint tema_13_introduccio_al_metabolisme.pdf 
            Ppoint tema_14_catabolisme_de_sucres_i_lipids.pdf 
            Ppoint tema_16_integracio_del_metabolisme.pdf 
            Ppoint tema_17_metabolisme_del_colesterol_i_lipids_especials.pdf 
            Ppoint tema_8_la_cel.lula_muscular.pdf 
            Ppoint tema_9_introduccion_al_genoma_humano.pdf 
            Ppoint tema_19_metabolisme_dels_nucleotids.pdf 
            Ppoint tema_11_introduccio_a_la_genetica.pdf 
            Ppoint tema_12_reproduccion_y_muerte_celular.pdf 
            Ppoint tema_20_introduccio_a_la_microbiologia.pdf 
            Ppoint ppoin_cc_transduccio_de_senyals.pdf 
            Ppoint tema_13_introduccio_al_metabolisme.pdf 
            Ppoint tema_15_metabolismo_de_las_proteinas.pdf 
            Ppoint tema_17_metabolisme_del_colesterol_i_lipids_especials.pdf 
            Ppoint tema_18_metabolisme_del_ferro.pdf 
            Ppoint tema_11_introduccio_a_la_genetica.pdf 
            Ppoint tema_20_introduccio_a_la_microbiologia.pdf 
            Ppoint tema_9_introduccion_al_genoma_humano.pdf 
            Ppoint tema_14_catabolisme_de_sucres_i_lipids.pdf 
            Ppoint tema_15_metabolismo_de_las_proteinas.pdf 
            Ppoint tema_16_integracio_del_metabolisme.pdf 
            Ppoint tema_17_metabolisme_del_colesterol_i_lipids_especials.pdf 
            Ppoint tema_18_metabolisme_del_ferro.pdf 
            Ppoint tema_19_metabolisme_dels_nucleotids.pdf 
            Ppoint tema_11_introduccio_a_la_genetica.pdf 
            Ppoint tema_12_reproduccion_y_muerte_celular.pdf 
            Ppoint tema_9_introduccion_al_genoma_humano.pdf 
            Ppoint ppoin_cc_transduccio_de_senyals.pdf 
            Ppoint tema_16_integracio_del_metabolisme.pdf 
            Ppoint tema_17_metabolisme_del_colesterol_i_lipids_especials.pdf 
            Movie contraction-musculairemp4.flv 
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            Movie calcium-myosin-muscle-contraction.flv 
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            Movie contraction-musculairemp4.flv 
            Movie calcium-myosin-muscle-contraction.flv 
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            Movie calcium-myosin-muscle-contraction.flv 
            Movie contraction-musculairemp4.flv 
            Movie calcium-myosin-muscle-contraction.flv 
            Movie contraction-musculairemp4.flv 
            Movie contraction-musculairemp4.flv 
            Movie calcium-myosin-muscle-contraction.flv 
            Movie calcium-myosin-muscle-contraction.flv 
            Vídeo traduccion_de_la_informacion_genetica.mov 
            Vídeo cel.lula.vlc 
            Vídeo micro1.wmv 
            Vídeo cel.lula.vlc 
            Vídeo micro2.avi 
            Vídeo micro1.wmv 
            Vídeo tema10arnai.mov 
            Vídeo micro2.avi 
            Vídeo micro1.wmv 
            Vídeo micro1.wmv 
            Vídeo cel.lula.vlc 
            Vídeo micro1.wmv 
            Vídeo micro2.avi 
            Vídeo micro2.avi 
            Vídeo tema10arnai.mov 
            Vídeo tema10arnai.mov 
            Vídeo cel.lula.vlc 
            Vídeo tema10arnai.mov 
            Vídeo cel.lula.vlc 
            Vídeo micro1.wmv 
            Vídeo micro2.avi 
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            Vídeo micro2.avi 
            Vídeo cel.lula.vlc 
            Vídeo cel.lula.vlc 
            Vídeo traduccion_de_la_informacion_genetica.mov 
            Vídeo tema10arnai.mov 
            Vídeo traduccion_de_la_informacion_genetica.mov 
            Vídeo traduccion_de_la_informacion_genetica.mov 
            Vídeo traduccion_de_la_informacion_genetica.mov 
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