General Anatomical Pathology
Main language of instruction: Spanish
Other languages of instruction: Catalan, English
If the student is enrolled for the English track then classes for that subject will be taught in the same language.
Head instructor
Dra. Maria Teresa FERNÁNDEZ - mfernandezf@uic.es
Office hours
Students can book an appointment by telephone or mail (contact phone: 5346 at the General Hospital of Catalonia, Pathology). Monday to Wednesday from 10 am to 13 pm.
Anatomic pathology is the science that studies causes and consequences of the disease, by analyzing the structural, functional, genetic and molecular changes in cells, tissues and organs, in correlation with the clinical presentation. Anatomic pathology provides the basis to understand the pathogenesis, clinical presentation, evolution and treatment of diseases and it is the discipline responsible of most of the diagnosis in tumor pathology and also in many non-neoplastic diseases.
The terms “Histopathology” or “Pathology” are often used as a synonym of anatomic pathology and the specialists in this area are denominated “Pathologists” or “Anatomopathologists”. Pathologists are much more than morphologists. Pathologist need to have a deep knowledge of the disease to be able to correlate morphomolecular findings with clinical information and radiology.
The subject of Anatomic Pathology includes General Pathology and Systemic Pathology. While General Pathology is focused in the study of basic cellular and tissue reactions in front of the disease (including neoplasia), Systemic Pathology analyzes the alterations specific of different cells, tissues and organs in front of the disease .
In this subject we will focus our attention to oral pathology and we will learn simultaneously the theoretical concepts and the practical aspects that contribute to the diagnosis.
Knowledge of histology so as to be able to identify pathological changes in tissues.
1: INTRODUCTION TO THE PATHOLOGY: What is Anatomic Pathology? What does a pathologist? (surgical pathology, cytopathology, autopsy, specimens for moleuclar tests and digital pathology) How are pathology reports and how to interpret them? Quality control. Tumor committees. Continuous education. Research.
2: GENERAL CONCEPTS OF CELLULAR PATHOLOGY: Parts of a cell. Types of cells. Agents and mechanisms of injury and cell necrosis . Apoptosis . Adaptation to stress, cell growth and differentiation . Intracellular accumulation (deposition diseases)
3: HISTOLOGY FROM THE ORAL CAVITY AND ACUTE INFLAMMATION: Concept and causes. Basic vascular and cellular reactions. Chemical mediators. Histology of the oral cavity and salivary glands in health and histopathological changes secondary to acute inflammation.
4: ACUTE AND CRONICAL INFLAMMATION (Part 2): Histopathological changes secondary to chronic inflammation. Granulomatous inflammation. Repair, regeneration and healing.
5: NON INFECTIOUS INFLAMMATORY DISEASES: Aphthous stomatitis. Lichen planus . Pemphigus vulgaris . Pemphigoid. Epidermolysis. Erythema multiforme .
6: INTRODUCTION TO THE ORAL MANIFESTATIONS OF SYSTEMIC DIASEASES: Oral granulomatosis and Crohn's disease, Benign migratory glositis, reactive arthritis (Reiter) Lupus erythematosus, Behçet disease. Sjogren's disease. Horton's arthritis and other vasculitis. Oral manifestations of lymphoproliferative disorders and systemic metastasis. Toxicity and drug reactions.
7: INFECTIOUS PATHOLOGY. VIRAL DISEASES: General aspects of infectious pathology Herpes virus infections, cytomegalovirus , human papilloma virus , Kaposi sarcoma and others
8. BACTERIAL, FUNGAL AND PARASITIC INFECTIONS: Types of inflammation: exudative, necrotizing, granulomatous and interstitial. Diagnostic methodologies. Bacterial infections: Staphylococcus, Pneumococcus, Meningococcus, Syphilis, Mycobacterial infections (Tuberculosis, M. avium, M. Intracelulare, M. Leprae), Actinomyces, Mycosis (Candida, Aspergillus, mucormicosis or Zigomicosisi), Leishmaniasis
9: NEOPLASIA: Definition, classification and nomenclature. Characteristics of benign and malignant tumors . Histological characteristics of tumors. Staging of cancer.
10: EPITHELIAL NON-ODONTOGENIC LESIONS: Tumors of the epithelium of surface and salivary glands.
11: ODONTOGENIC AND EMBRIONAL CYSTS AND ODONTOGENIC TUMORS (Part 1): Dental histology (Enamel. Dentin. Cement. Dental pulp. Periodontal ligament. Alveolar bone). Odontogenic and embrional cysts and odontogenic tumors.
12: ODONTOGENIC AND EMBRIONAL CYSTS AND ODONTOGENIC TUMORS (Part 2): Dental histology (Enamel. Dentin. Cement. Dental pulp. Periodontal ligament. Alveolar bone). Odontogenic and embrional cysts and odontogenic tumors.
13: NON-EPITELIAL NEOPLASTIC ORAL PATHOLOGY AND PATHOLOGY OF TOOTH AND JAW (Part 1): Benign and malignant pigmented lesions. Soft tissue tumors. Hematologic disorders. Tooth and jaw pathology
14: NON-EPITELIAL NEOPLASTIC ORAL PATHOLOGY AND PATHOLOGY OF TOOTH AND JAW (Part 2): Benign and malignant pigmented lesions. Soft tissue tumors. Hematologic disorders. Tooth and jaw pathology
15: SEMINAR OF IMAGES
E: exam date | R: revision date | 1: first session | 2: second session: