Facultat de Medicina i Ciències de la Salut
Departament de Ciències Bàsiques de Ciències de la Salut
Fotografia del professor

Formació Acadèmica del Dr. ALDEA MALO, Martí

  • Otros
    Universitat Autònoma de Barcelona

Publicacions del Dr. ALDEA MALO, Martí


  • Moreno, D.; Jenkis, K.; Morlot, S.; Charvin, G.; Csikasz-Nagy, A.; Aldea, M., 2019, "Proteostasis collapse, a hallmark of aging, hinders the chaperone-Start network and arrests cells in G1", eLife, 8.
  • Moreno, D.; Parisi, E.; Yahya, G.; Vaggi, F.; Csikász, A.; Aldea, M., 2019, "Competition in the chaperone-client network subordinates cell-cycle entry to growth and stress", Life Science Alliance, 2.
  • Moreno, D.; Aldea, M., 2019, "Coincidence analysis of molecular dynamics by raster image correlation spectroscopy", Methods in Molecular Biology, 2040, 375-384.
  • Parisi, E.; Yahya, G.; Flores, A.; Aldea, M., 2018, "Cdc48/p97 segregase is modulated by cyclin-dependent kinase to determine cyclin fate during G1 progression", Embo journal, 37.
  • Martínez-Laínez, JM.; Moreno, D.; Parisi, E.; Clotet, J.; Aldea, M., 2018, "Centromeric signaling proteins boost G1 cyclin degradation and modulate cell size in budding yeast", PLOS biology, 16.
  • Aldea, M.; Jenkins, K.; Csikász, A., 2017, "Growth Rate as a Direct Regulator of the Start Network to Set Cell Size", Frontiers in cell and developmental biology, 5, 57-62.
  • Aldea, M., 2017, "Compartmentalization of ER-bound chaperone confines protein deposit formation to the aging yeast cell", Current biology, 27, 773-783.
  • Deniz, Ö.; Flores, Ó.; Aldea, M.; Soler-López, M.; Orozco, M., 2016, "Nucleosome architecture throughout the cell cycle", Scientific Reports, 6, 1-11.
  • Georgieva, M.V.; Yahya, G.; Codó, L.; Ortíz, R.; Gallego, C.; Orozco, M.; Aldea, M., 2015, "Inntags: small self-structured epitopes for innocuous protein tagging", Nature methods, 12, 955-958.
  • Yahya, G.; Parisi, E.; Flores, A.; Gallego, C.; Aldea, M., 2014, "A Whi7-anchored loop controls de G1 Cdk-cyclin complex at Start.", Molecular cell, 53, 115-126.
  • Menoyo, S.; Ricco, N.; Bru, S.; Hernández-Ortega, S; Escoté, X.; Aldea, M.; Clotet, J., 2013, "Phosphate-Activated Cyclin-Dependent Kinase Stabilizes G(1) Cyclin To Trigger Cell Cycle Entry", Mol Cell Biol., 33(7), 1273-1284.
  • Ferrezuelo, F.; Colomina, N.; Palmisano, A.; Garí, E.; Gallego, C.; Csikasz-Nagy, A.; Aldea, M., 2012, "The critical size is set at a single-cell level by growth rate to attain homeostasis and adaptation", Nature communications, 3, 1-11.
  • Ferrezuelo, F.; Colomina, N.; Futcher, B.; Aldea, M., 2010, "The transcriptional network activated by Cln3 cyclin at the G1-to-S transition of the yeast cell cycle", Genome biology, 11, 1-9.
  • Vergés, E.; Colomina, N.; Garí, E.; Gallego, C.; Aldea, M., 2007, "Cyclin Cln3 is retained at the ER and released by the J chaperone Ydj1 in late G1 to trigger cell cycle entry", Molecular cell, 26, 649-662.
  • Clotet, J.; Escoté, X.; Adrover, MÀ; Yaakov, G.; Garí, E.; Aldea, M.; De Nadal, E.; Posas, F., 2006, "Phosphorylation of Hsl1 by Hog1 leads to a G2 arrest essential for cell survival at high osmolarity.", Embo journal, 25, 2338-2346.
  • Clotet, J.; Garí, E.; Aldea, M.; Ariño, J., 1999, "The yeast Ser/Thr phosphatases SIT4 and PPZ1 play opposite roles in the regulation of the cell cycle.", Molecular and cellular biology, 19, 2408-2415.

Projectes de recerca del Dr. ALDEA MALO, Martí

  • Proteotoxic aggregates, chaperome alterations and cell proliferation decline during cell aging.
  • Prions and aggregons as inhibitors of Start: a path to cell ageing..