Universitat Internacional de Catalunya - Barcelona

Human Biology 1

• code 07870
• course 1
• term Semester 1
• type FB
• credits 6

Module: Basic biomedical sciences relevant in dentistry

Matter: Genetics, Biochemicals and Molecular Biology

Main language of instruction: Spanish

Other languages of instruction: Catalan, English

If the student is enrolled for the English track then classes for that subject will be taught in the same language.

Head instructor

Dr. Víctor Manuel DÍAZ - vmdiaz@uic.es

Office hours

Dr. Bernhard Knapp (bknapp@uic.es)

Human Biology I contains part of the basic knowledge in the Health Sciences that an undergraduate dentistry student needs to acquire.

The aim is for the student to achieve a basic understanding of the molecular bases of life, describing the structure and function of biomolecules, their metabolism and regulation.

Knowledge of Biology and Chemistry at sixth-form level.

• To ensure students acquire the knowledge and competence required, once graduated, to be able to carry out general dental practice in an independent manner. At the same time they should be able to recognize their limitations and when faced with situations exceeding their abilities, seek advice or refer the patient to another professional.
• Promote the acquisition of knowledge, skills, attitudes and professional behaviours that facilitate effective and appropriate interaction with patients, colleagues and other health professionals.
• Promote acquisition of knowledge, skills and attitudes that promote learning throughout life in an effective way to allow adequate professional development.
• Promote research in dentistry and ongoing training in the study of new techniques and improvements in the dental profession.

• 11 - Understanding the basic biomedical science Dentistry is based on in order to ensure that adequate dental healthcare is provided.
• 12 - Understanding and recognising the structure and normal function of the stomatognathic apparatus, at a molecular, cellular, tissue and organic level, during the various stages of life.
• 14 - Being aware of the general processes of the illness, including infection, inflammation, alterations in the immune system, degeneration, neoplasm, metabolic alterations and genetic disorders.
• 18 - Being aware of, critically evaluating and knowing how to use sources of clinical and biomedical infomation in order to obtain, organise, interpret and communicate scientific and healthcare-related information.
• 19 - Being aware of scientific methods and having the critical ability to evaluate established knowledge and innovative information. Being able to formulate hypotheses, collect and critically evaluate information in order to resolve problems, in accordance with scientific methods.
• 34 - Knowing about scientific methods and having the critical ability to evaluate established knowledge and new information
• 08 - Knowing how to share information with other healthcare professionals and how to work as part of a team.
• 29 - Recognising the underlying causes of dental health in the population, whether genetic, lifestyle, demographic, environmental, social, economic, psychological or cultural.
• 32 - Knowing the biomedical science on which Dentistry is based in order to ensure adequate oral and dental care. This science must include material on: (a). Embryology, anatomy, histology and the physiology of the human body (b). Genetics, Biochemistry, Cell and Molecular Biology and (c). Microbiology and immunology.
• 38 - Being aware of clinical and laboratory-based procedures and diagnostic tests, knowing their reliability and diagnostic viability and being competent in interpreting the results
• 13 - Understanding and recognising the science behind the essential bio-materials involved in dental practice as well as immediately managing potential allergies to these.

• Clearly understand the basic biomedical sciences on which Dentistry is founded to ensure proper oral and dental care.
• Understand the general processes causing illness, including genetic and metabolic disorders.
• Understand the scientific method and acquire the critical capacity to value established knowledge and new information.
• Acquire the basics to evaluate the basic published research.
• Improve in the use of contemporary information technologies.
• Be aware of diagnostic laboratory tests, their diagnostic reliability and validity, and be able to interpret their results.
• Learn to value the need for life-long learning.

• 1.04 - Know the organization of our immune system: molecules, cells and organs
• 1.28 - Solve clinical problems from deductions made from the basic knowledge of anatomy and function of the teeth
• 1.29 - Identify using image techniques, structures of the different topographical regions of the oral cavity and teeth in particular
• 1.30 - Understand the basic bio-medical sciences on which dentistry is based to ensure proper oral-dental care.
• 1.31 - - Understand and recognize the structure and normal function of the stomatognatic apparatus at a molecular and cellular level
• 1.32 - Will know the general processes of falling ill, including genetic alterations
• 1.33 - Will know better the scientific method and will have critical capacity to assess the established knowledge and new information
• 1.34 - Will get the rudiments to assess published basic research
• 1.35 - Will manage better than at the beginning of the subject, contemporary information technologies
• 1.36 - – Will know genetic diagnostic testing of laboratory, its reliability and diagnostic validity and begin to be able to interpret the results
• 1.37 - Will value as necessary the knowledge throughout life
• 1.38 - Will start to understand the biochemical behavior of the essential bio-materials for dental practice
• 1.39 - Will learn the general processes of falling ill, including metabolic alterations.
• 1.40 - Will know the clinical biochemistry tests, its reliability and diagnostic validity and begin to be able to interpret their results

The contents of the course are structured in 3 main groups: biomolecules, enzymology and metabolism.These will be supported by Clinical Cases (CC).

Chapter 1 Introduction

Chapter 2 Intracellular media

Chapter 3 Carbohydrates

Chapter 4 Lipids

Chapter 5 Nucleic Acid

Chapter 6 Amino acids

Chapter 7 Enzymes

Chapter 8 Biochemistry principles

Chapter 9 Glucid metabolism

Chapter 10 Carboxilic acids cycle

Chapter 11 Electronic transport

Chapter 12 Carbohydrates biosynthesis

Chapter 13 Lipid metabolism

Chapter 14 Lipid biosynthesis

Chapter 15 Amino acid metabolism

Chapter 16 Nucleotid metabolism

Chapter 17 Integration of metabolism

The contents of the course will be taught through the following activities:

Lecture: Presentations of theory and exercises of a general nature given by the teacher to the whole year group. All semester, 3 hours / week.

Lecturer: Dr. Bernhard Knapp

Clinical Case Seminar: Presentation of a topic (case report) by the students. One group. All semester, 1 hour / week per group. Lecturer: Dr. Bernhard Knapp

Laboratory: Practical laboratory sessions. 1 week (three days in the afternoon) for each group. Lecturer: Dr. Bernhard Knapp

Progress test: 10% of the final grade

Clinical cases: 20% of the final grade, mandatory attendance

Practical laboratory sessions: 10% of the final grade. The practical sessions are mandatory.

Final exam: 60% of the final grade. A minimum grade of 5 is needed to do average with the other parts of the subject.

Lehninger  PRINCIPLES OF BIOCHEMISTRY. Nelson, D. L., Cox, M. M. W.H. Freeman and Company. 5th edition, 2008.

ESSENTIAL CELL BIOLOGY. Alberts, B., Bray, D., Hopkin, K., Johnson, A., Lewis, J., Raff, M., Roberts, K., Walter, P. Garland Science. 4th edition, 2014.

E: exam date | R: revision date | 1: first session | 2: second session:

• E1 17/01/2020 08:00h A01
• E1 17/01/2020 08:00h A02
• E1 17/01/2020 08:00h A03
• R1 22/01/2020 13:00h A01
• R1 22/01/2020 14:00h A01
• E2 19/06/2020 08:00h A01
• R2 03/07/2020 08:00h A01