Subject

Human Biology 2

  • code 07871
  • course 1
  • term Semester 1
  • type FB
  • credits 6

Module: Basic biomedical sciences relevant in dentistry

Matter: Genetics, Biochemicals and Molecular Biology

Main language of instruction: Spanish

Other languages of instruction: Catalan, English

If the student is enrolled for the English track then classes for that subject will be taught in the same language.

Teaching staff

Head instructor

Dr. Bernhard KNAPP - bknapp@uic.es
Dr. Miguel BAENA - mbaena@uic.es

Office hours

Dr. Bernhard Knapp (bknapp@uic.es)

Dr. Miguel Baena (mbaena@uic.es)

Introduction

The aim of this subject is to introduce students to the main molecular bases of cellular communication. To understand the behaviour of the cells as non-isolated units integrated in tissue, it is essential to know what happens in their interior and how this activity is influenced by the surrounding medium. To this end, the students must know the cellular components, the transport mechanisms that regulate cell content, the signalling pathways that control mechanisms such as cell growth and proliferation, and the processes that can be triggered when this regulation is lost, such as in cancer. The final section of this subject, entitled "oral biology", goes deeper into those aspects of biochemistry and molecular and cell biology which directly affect dental practice as well as the understanding of the normal and pathological workings of the organs affected. In order to introduce to and familiarise the students with scientific research applied to dentistry, they will carry out a work of critical reading and understanding of a scientific paper, which will be presented at the end of the semester in the form of a poster. Related to this same objective, the course includes several practical sessions where the students will be introduced to, and carry out, some of the techniques used in both diagnosis and current biomedical research.

Pre-course requirements

Knowledge of Biology and Biochemistry at sixth-form level.

Objectives

Knowledge:

The aim of this course is to go deeper into the biochemical and molecular aspects upon which knowledge in any area of the health sciences is based.

On finishing this course, the student must know:

-The mechanism of communication between cells, the transmission of cellular signals, the molecular bases of division and cell death, and the biological mechanisms involved in cancer.

-The structure and composition of dental tissues.

-The basic principles that determine the inheritance of diseases affecting the oral and dental environment. 

Intellectual and practical skills: 

-Become familiar with the scientific method. 

-Promote reasoning and the discussion of problems. 

-Integrate knowledge into practical laboratory tasks. 

-Know the main sources of information and resources available to update the knowledge acquired. 

Attitude: 

This is the last semester in which the student will take a compulsory subject of Biochemistry and Molecular Biology. It is therefore intended that the student, upon finishing this subject, has understood the importance of this area of knowledge in the development of the other subjects of the degree and the Health Sciences in general, since any pathology of living beings is defined ultimately at the biochemical and molecular level.

Competences / Learning outcomes of the degree programme

  • 11 - Understanding the basic biomedical science Dentistry is based on in order to ensure that adequate dental healthcare is provided.
  • 14 - Being aware of the general processes of the illness, including infection, inflammation, alterations in the immune system, degeneration, neoplasm, metabolic alterations and genetic disorders.
  • 18 - Being aware of, critically evaluating and knowing how to use sources of clinical and biomedical infomation in order to obtain, organise, interpret and communicate scientific and healthcare-related information.
  • 19 - Being aware of scientific methods and having the critical ability to evaluate established knowledge and innovative information. Being able to formulate hypotheses, collect and critically evaluate information in order to resolve problems, in accordance with scientific methods.
  • 34 - Knowing about scientific methods and having the critical ability to evaluate established knowledge and new information
  • 08 - Knowing how to share information with other healthcare professionals and how to work as part of a team.
  • 12 - Understanding and recognising the structure and normal function of the stomatognathic apparatus, at a molecular, cellular, tissue and organic level, during the various stages of life.
  • 33 - Knowing the morphology and function of the stomatognathic apparatus, including material on embriology, anatomy, histology and specific physiology
  • 38 - Being aware of clinical and laboratory-based procedures and diagnostic tests, knowing their reliability and diagnostic viability and being competent in interpreting the results

Learning outcomes of the subject

- Knowledge of the essential aspect of the basic Biology.
- Understand the scientific method

-Acquisition of the critical capacity to know the current available information based on scientific research in the field of Dentistry.
-Know the laboratory tests for diagnostic and became able to interpret the results.

Be familiar with the essential elements of basic biology on which dentistry is based.
Be familiar with the scientific method and acquire the critical ability to be aware of the most up-to-date information based on scientific research in the field of dentistry.
Be familiar with laboratory diagnostic tests,  their diagnostic reliability and validity and be able to interpret their results.

  • 1.04 - Know the organization of our immune system: molecules, cells and organs
  • 1.09 - - Know the structure and function of communication and control systems, nervous system and endocrine
  • 1.30 - Understand the basic bio-medical sciences on which dentistry is based to ensure proper oral-dental care.
  • 1.32 - Will know the general processes of falling ill, including genetic alterations
  • 1.33 - Will know better the scientific method and will have critical capacity to assess the established knowledge and new information
  • 1.34 - Will get the rudiments to assess published basic research
  • 1.35 - Will manage better than at the beginning of the subject, contemporary information technologies
  • 1.36 - – Will know genetic diagnostic testing of laboratory, its reliability and diagnostic validity and begin to be able to interpret the results
  • 1.37 - Will value as necessary the knowledge throughout life
  • 1.38 - Will start to understand the biochemical behavior of the essential bio-materials for dental practice
  • 1.39 - Will learn the general processes of falling ill, including metabolic alterations.
  • 1.10 - Know the structure and function of the organs and systems involved in maintaining the homeostasis of the human body. Circulatory, respiratory, digestive and urinary apparatus.
  • 1.19 - Solve clinical problems from deductions made from the basic knowledge of anatomy and physiology of the head and neck
  • 1.25 - Know the different tissues that make up the teeth, distribution and histologic features.
  • 1.31 - - Understand and recognize the structure and normal function of the stomatognatic apparatus at a molecular and cellular level
  • 1.40 - Will know the clinical biochemistry tests, its reliability and diagnostic validity and begin to be able to interpret their results

Syllabus


Chapter 1 MOLECULAR TECHNIQUES

Chapter 2 CELLULAR STRUCTURES

Chapter 3 CELL CYCLE

Chapter 4 CELLULAR TRANSPORT

Chapter 5 CELLULAR SIGNALLING

Chapter 6 CYTOSKELETON

Chapter 7 EXTRACELLULAR MATRIX

Chapter 8 INHERITANCE

Chapter 9 STEM CELLS AND CANCER

Chapter 10 ORAL BIOLOGY

Teaching and learning activities

Evaluation systems and criteria

Bibliography and resources

ESSENTIAL CELL BIOLOGY. Alberts, B., Bray, D., Hopkin, K., Johnson, A., Lewis, J., Raff, M., Roberts, K., Walter, P. Garland Science. 4th edition, 2014.

 

Lehninger  PRINCIPLES OF BIOCHEMISTRY. Nelson, D. L., Cox, M. M. W.H. Freeman and Company. 5th edition, 2008.

Evaluation period

E: exam date | R: revision date | 1: first session | 2: second session:

  • E1 17/01/2019 10:00h A13
  • E1 17/01/2019 10:00h A01
  • E1 17/01/2019 10:00h A03
  • E1 17/01/2019 10:00h A10
  • R1 21/01/2019 14:00h A11
  • E2 19/06/2019 10:00h A01
  • R2 01/07/2019 12:00h A02
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