General Anatomical Pathology
Main language of instruction: Spanish
Other languages of instruction: Catalan, English
If the student is enrolled for the English track then classes for that subject will be taught in the same language.
Head instructor
Dra. Maria Teresa FERNÁNDEZ - mfernandezf@uic.es
Office hours
Students can book an appointment by telephone or mail (contact phone: 5346 at the General Hospital of Catalonia, Pathology). Monday to Wednesday from 10 am to 13 pm.
Anatomic pathology is the science that studies causes and consequences of the disease, by analyzing the structural, functional, genetic and molecular changes in cells, tissues and organs, in correlation with the clinical presentation. Anatomic pathology provides the basis to understand the pathogenesis, clinical presentation, evolution and treatment of diseases and it is the discipline responsible of most of the diagnosis in tumor pathology and also in many non-neoplastic diseases.
The terms “Histopathology” or “Pathology” are often used as a synonym of anatomic pathology and the specialists in this area are denominated “Pathologists” or “Anatomopathologists”. Pathologists are much more than morphologists. Pathologist need to have a deep knowledge of the disease to be able to correlate morphomolecular findings with clinical information and radiology.
The subject of Anatomic Pathology includes General Pathology and Systemic Pathology. While General Pathology is focused in the study of basic cellular and tissue reactions in front of the disease (including neoplasia), Systemic Pathology analyzes the alterations specific of different cells, tissues and organs in front of the disease .
In this subject we will focus our attention to oral pathology and we will learn simultaneously the theoretical concepts and the practical aspects that contribute to the diagnosis.
Knowledge of histology so as to be able to identify pathological changes in tissues.
1: INTRODUCTION TO THE PATHOLOGY: What is Anatomic Pathology? What does a pathologist? (surgical pathology, cytopathology, autopsy and digital pathology) How are pathology reports and how to interpret them?
2: GENERAL CONCEPTS OF CELLULAR PATHOLOGY: Agents and mechanisms of injury and cell necrosis . Apoptosis . Adaptation to cell growth and differentiation . Intracellular accumulation (deposition diseases)
3: ACUTE AND CRONICAL INFLAMMATION (Part 1): Concept and causes. Basic vascular and cellular reactions. Chemical mediators. Histology of the oral cavity and salivary glands in health and histopathological changes secondary to acute and chronic inflammation. Repair, regeneration and healing.
4: ACUTE AND CRONICAL INFLAMMATION (Part 2): Concept and causes. Basic vascular and cellular reactions. Chemical mediators. Histology of the oral cavity and salivary glands in health and histopathological changes secondary to acute and chronic inflammation. Repair, regeneration and healing.
5: NON INFECTIOUS INFLAMMATORY DISEASES: Aphthous stomatitis. Lichen planus . Pemphigus vulgaris . Pemphigoid. Epidermolysis. Erythema multiforme .
6: INTRODUCTION TO THE ORAL MANIFESTATIONS OF SYSTEMIC DIASEASES : Sjögren disease . Behçet disease. Horton Arteritis and other vasculitis. Drug reactions
7: INFECTIOUS PATHOLOGY. VIRAL DISEASES: General aspects of infectious pathology Herpes virus infections, cytomegalovirus , human papilloma virus , Kaposi sarcoma
8. BACTERIAL, FUNGAL AND PARASITIC INFECTIONS: Oral and systemic bacterial infections (including mycobacteria, actinomyces, nocardia). Fungal infections (candida, aspergillum, mucormicosis) and parasitic (leishmania, ameba and pediculosis)
9: NEOPLASIA: Definition, classification and nomenclature. Characteristics of benign and malignant tumors . Cancer epidemiology . Hereditary cancer. Precancerous lesions. Etiological factors of cancer. Clinical characteristics of tumors. Staging of cancer.
10: EPITHELIAL NON-ODONTOGENIC LESIONS: Tumors of the epithelium of surface and salivary glands.
11: ODONTOGENIC AND EMBRIONAL CYSTS AND ODONTOGENIC TUMORS (Part 1): Dental histology (Enamel. Dentin. Cement. Dental pulp. Periodontal ligament. Alveolar bone). Odontogenic and embrional cysts and odontogenic tumors.
12: ODONTOGENIC AND EMBRIONAL CYSTS AND ODONTOGENIC TUMORS (Part 2): Dental histology (Enamel. Dentin. Cement. Dental pulp. Periodontal ligament. Alveolar bone). Odontogenic and embrional cysts and odontogenic tumors.
13: NON-EPITELIAL NEOPLASTIC ORAL PATHOLOGY AND PATHOLOGY OF TOOTH AND JAW (Part 1): Benign and malignant pigmented lesions. Soft tissue tumors. Hematologic disorders. Tooth and jaw pathology
14: NON-EPITELIAL NEOPLASTIC ORAL PATHOLOGY AND PATHOLOGY OF TOOTH AND JAW (Part 2): Benign and malignant pigmented lesions. Soft tissue tumors. Hematologic disorders. Tooth and jaw pathology
15: SEMINAR OF IMAGES
English classes will be in person
There will be 14 theoretical classes with discussion of cases and clinical-pathological correlation and before finishing some classes a mini test of 2-3 questions with computer will be done. In the last class an image seminar will be held.
An optional visit to the Department of Pathology will be organized over the first weeks to facilitate the understanding of the first class.
To pass the course it is necessary to get a minimum of 5 points overall final grade. The final mark will be the mark obtained in the final theoretical and practical exam. There will be a multiple choice test consisting of questions of theoretical and practical images
The grades obtained by continuous evaluation of the progress during the classes will be positively considered.
Evaluation of grades:
a) Failed: 0- 4,9 (SS)
b) Pass: 5-6,9 (AP)
c) Remarkable: 7-8,9 (NT)
d) Outstanding: 9-10 (SB).
e) Special distinction: Implies having obtained an outstanding qualitification.
During exams, consultation with a small textbook and/or photocopied notebook is permitted. Each student must bring his own materials and cannot share them. Internet connection by phone or any other means is not allowed.
E: exam date | R: revision date | 1: first session | 2: second session: