ROCHE VALLES, David

Dr.
David
ROCHE
VALLES
Facultat de Ciències Econòmiques i Socials
Departament d'Economia i Organització d'Empreses
Lector
Extensió: 
droche@uic.es
Fotografia del professor

Formació Acadèmica del Dr. ROCHE VALLES, David

  • LLICENCIAT EN MATEMÀTIQUES
    universitat autònoma de barcelona (2004)
  • SUFICIÈNCIA INVESTIGADORA EN CIÈNCIES DE LA COMPUTACIÓ I INTEL·LIGÈNCIA ARTIFICIAL
    (2007)
  • DOCTOR EN INFORMÀTICA
    Universitat Autònoma de Barcelona (2015)
  • MÀSTER EN INICIACIÓ A LA RECERCA EN INTEL·LIGÈNCIA ARTIFICIAL

Publicacions del Dr. ROCHE VALLES, David

Articles

  • Burgueño, J.; Pujol, M.; Monroy, X.; Roche, D.; Valera, M.; Merlos, M.; Giraldo, J., 2017, "A Complementary Scale of Biased Agonism for Agonists with Differing Maximal Responses", Scientific Reports, 7.
  • Roche, D.; Van der Graaf, PH; Giraldo, J., 2016, "Have many estimates of efficacy and affinity been misled? Revisiting the operational model of agonism", Drug discovery today, 21, 1735-1739.
  • Gil, D.; Roche, D.; Borras, Agnes; Giraldo, J., 2015, "Terminating evolutionary algorithms at their steady state", Computational optimization and applications, 61, 489-515.
  • Roche, D.; Gil, D.; Giraldo, J., 2014, "Mathematical Modeling of G Protein-Coupled Receptor Function: What Can We Learn from Empirical Mechanistic Models?", Advances in experimental medicine and biology, 796, 159-181.
  • Lans, I.; Dalton, J.; Rovira, X.; Roche, D.; Giraldo, J., 2014, "Metabotropic, Glutamate Receptors: a Challenging System for Computational Modeling", Current neuropharmacology, 12, 33-34.
  • Roche, D.; Gil, D.; Giraldo, J., 2013, "Mechanistic analysis of the function of agonists and allosteric modulators: Reconciling two-state and operational models", British journal of pharmacology, 169, 1189-1202.
  • Roche, D.; Gil, D.; Giraldo, J., 2013, "Multiple active receptor conformation, agonist efficacy and maximum effect of the system: the conformation-based operational model of agonism", Drug discovery today, 18, 365-371.
  • Hernandez-Sabaté, A.; Gil, D.; Roche, D.; Matsumoto, M.; Furuie, S., 2011, "Computer Analysis of Images and Patterns: 14th International Conference, CAIP 2011", Lecture notes in computer science, 6854, 520-528.
  • Rovira, X.; Serra, J.; Roche, D.; Giraldo, J., 2009, "Functional Implications of G Protein-Coupled Receptors Oligomerization Under the Cooperativity Concept", Journal of neurochemistry, 110, 171.
  • Rovira, X.; Vivó, M.; Serra, J.; Roche, D.; Strange, P.; Giraldo, J., 2009, "Modelling the interdependence between the stoichiometry of receptor oligomerization and ligand binding for coexisting dimer/tetramer receptor system", British journal of pharmacology, 156, 28-35.
  • Garcia, JA.; Bartomeus, F.; Roche, D.; Giraldo, J.; Stanley, HE.; Casamayora, E., 2008, "Ecophysiological significance of scale-dependent patterns in prokaryotic genomes unveiled by a combination of statistic analyses", Genomics, 91, 538-543.
  • Rovira, X.; Roche, D.; Serra, J.; Kniazeff, J.; Pin, J.; Giraldo, J., 2008, "Modeling the binding and function of metabotropic glutamate receptors", Journal of pharmacology and experimental therapeutics, 325, 443-456.
  • Rovira, X.; Roche, D.; Pin, J.; Giraldo, J., 2008, "Modelling the function of metabotropic glutamate receptors allosteric modulators", Methods and findings in experimental and clinical pharmacology, 30, 78.
  • Giraldo, J.; Serra, J.; Roche, D.; Rovira, X., 2007, "Assessing receptor affinity for inverse agonists:Schild and Cheng-Prusoff methods revisited", Current drug targets, 8, 197-202.
  • Giraldo, J.; Roche, D.; Rovira, X.; Serra, J., 2006, "The catalytic power of enzymes: Conformational selection or transition state stabilization?", Febs letters, 580, 2170-2177.

Projectes de recerca del Dr. ROCHE VALLES, David

  • Estilos de vida no saludables: herramientas para el análisis de políticas de salud.