Universitat Internacional de Catalunya
Genetics
Other languages of instruction: Catalan, English
Teaching staff
The student will be able to consult questions to the professors at the end of each class. Outside these hours, you must request an appointment by email:
Dra. Mayka Sanchez (msanchezfe@uic.es)
Introduction
Medicine is a field that changes constantly, therefore, more than ever, nowadays; the basic knowledge is necessary, which helps the professional to face any situation. In this sense, knowing the genetic origin of the main pathologies is essential to perform a correct analysis of the etiology, diagnosis and evaluation of therapeutic processes.
This subject intends to give the medical student an introductory vision on basic aspects of medical genetics. It is oriented in a practical way, it tries to prioritize in each subject those concepts and situations that best adapt to the understanding of phenomena associated with the professional practice in the field of Medicine.
Pre-course requirements
The subject, which is attended the first year of the degree, does not require any specific administrative requirements. In spite of everything, in order to be able to develop the subject successfully, it would be necessary to have previous knowledge of molecular biology and cellular level of second-level baccalaureate.
Objectives
The objective of this subject is the introductory treatment of basic genetic aspects and genetic aspects related to health. The student, when the subject is finished, will have to understand the main genetic laws that govern the transmission of hereditary pathologies and the biochemical and molecular aspects associated with the transmission of genetic information.
Competences/Learning outcomes of the degree programme
Learning outcomes of the subject
At the end of the course, the student:
- Learn about the mechanisms for storage and processing of genetic information, as well as the different levels of organization of the human genome.
- Know and apply the basis of genetics, as well as their methods, in the study of genetic pathologies.
Syllabus
Topic 1. Introduction to Human Genetics
Topic 2. DNA Replication
Topic 3. Transcription and Translation control on gene expression and diseases
Topic 4. Mitosis, Meiosis, Sexual Reproduction and recombination
Case Method (CM) 1: Mitosis, meiosis concepts and problems (problems)
Topic 5. Mendelian genetics and monogenic inheritance patterns
Case Method (CM) 2: Genetic debate
Topic 6. Extensions of Mendelian genetics
Case Method (CM) 4: Chromosomal alterations- Cytogenetics (Problem, CM)
Topic 7. Non-Mendelian inheritance and phenotypic expression variants
Case Method (CM) 3: Calculation of the risk of transmission in monogenic inherited diseases- part II (Problem, CM)
Topic 8. Human genome, Mutations and Diseases
Case Method (CM) 6: Clinical cases in human diseases part II (Problem, CM)
Topic 9. Cancer genetics
Case Method (CM) 7: Cancer genetics- clinical cases
Topic 10 Epigenetics
Case Method (CM) 8: Epigenetics and Cancer genetics- clinical cases
Topic 11. Quantitative Genetics
Case Method (CM) 9: Quantitative Genetics – Problems
Case Method (CM) 5: Clinical cases in human diseases part I- Use of Databases (Problem, CM)
Topic 12. Population and evolutionary genetics
Case Method (CM) 10: Population and evolutionary genetics – Problems
Topic 13 Multifactorial inheritance (virtual)
Case Method (CM) 11: Genetics-breaking news (clinical case)
Teaching and learning activities
In blended
- Theory classes (lectures and cases): online (in streaming). Half of the students in the classroom and half of the students online. By using Collaborate on Moodle. - Practical classes: face-to-face class in small groups.
Bibliography and resources
SUDBERY. Genética molecular humana. Ed. Pearson.
KLUG. Conceptos de genética. Ed. Pearson.
PIERCE. Genética. Un enfoque conceptual. Ed. Médica Panamericana.
PIERCE. Fundamentos de Genética, conceptos y relaciones. Ed. Médica Panamericana.
Evaluation period
- E1 04/06/2021 I3 11:00h
- E2 29/06/2021 14:00h