Directorio
RODRÍGUEZ RODRÍGUEZ, Rosalía
Ext. 5221
Departamento de Ciencias Básicas
From cell metabolism to metabolic diseases (METADIS)
RODRÍGUEZ RODRÍGUEZ, Rosalía
CV
Perfil del profesor
Professor Agregat o Titular
Ciencias Básicas, DEPARTAMENTO DE CIENCIAS BÁSICAS. Universitat Internacional de Catalunya
Formación académica
- Doctorat en Farmacia (2006) Universidad de Sevilla
- Licenciada en Farmacia Universidad de Sevilla
- Experto Universitario en Atención Farmacéutica Universidad de Sevilla
Publicaciones
Artículos
- Esterhuizen, M.; Park, C.; Kim, Y.; Kim, T.; Yoon, H.; Andres, F.; Rodriguez-Rodriguez, R.; Tanabe, S., (2023), "A perspective on the role of physiological stresses in cancer, diabetes and cognitive disease as environmental diseases", Frontiers in Molecular Biosciences, vol. 10, ISSN: 2296-889X.
- Garcia, J.; Paraiso, W.; Zagmutt, S.; Fosch, A.; Reguera, AC.; Alzina, S.; Sánchez, L.; Fukushima, S.; Toh, K.; Casals, N; Serra, D.; Herrero, L.; Garcia, J.; Kataoka, K.; Ariza, X.; Quader, S.; Rodriguez-Rodriguez, R., (2023), "Nanomedicine targeting brain lipid metabolism as a feasible approach for controlling the energy balance", Biomaterials science, vol. 11, pp. 2336-2347, ISSN: 2047-4830.
- Rodriguez-Rodriguez, R.; Fosch, A.; Garcia, J.; Zagmutt, S.; Casals, N, (2023), "Targeting carnitine palmitoyltransferase 1 isoforms in the hypothalamus: A promising strategy to regulate energy balance", JOURNAL OF NEUROENDOCRINOLOGY, vol. 35, No. 9, ISSN: 1365-2826.
- Fadó, R.; Zagmutt, S.; Herrero, L.; Muley, H.; Rodriguez-Rodriguez, R.; Bi, H.; Serra, D.; Casals, N, (2023), "To be or not to be a fat burner, that is the question for cpt1c in cancer cells", Cell death and disease, vol. 14, No. 1, ISSN: 2041-4889.
- Fosch, A.; Rodriguez, M.; Miralpeix, C.; Zagmutt, S.; Larrañaga, M.; Reguera, AC.; Garcia, J.; Herrero, L.; Serra, D.; Casals, N; Rodriguez-Rodriguez, R., (2023), "Central Regulation of Brown Fat Thermogenesis in Response to Saturated or Unsaturated Long-Chain Fatty Acids", International Journal of Molecular Sciences, vol. 24, No. 2, ISSN: 1422-0067.
- Rinaldi de Alvarenga, J.; Garcia, M.; Ulaszewska, M.; Zagmutt, S.; Perez-Montero, M.; Vrhovsek, U.; Lamuela Raventos, R.; Rodriguez-Rodriguez, R., (2022), "Integrated Metabolomics, Lipidomics, and Genomics Reveal the Presence of a New Biomarker, Butanediol Glucuronide, Associated with the Activation of Liver Ketogenesis and Lipid Oxidation by Tomato-Based Sofrito in Obese Rats", Antioxidants, vol. 11, No. 11, ISSN: 2076-3921.
- Claro-Cala, C.; Jiménez-Altayó, F.; Zagmutt, S.; Rodriguez-Rodriguez, R., (2022), "Molecular Mechanisms Underlying the Effects of Olive Oil Triterpenic Acids in Obesity and Related Diseases", Nutrients, vol. 14, No. 8, ISSN: 2072-6643.
- Rodriguez-Rodriguez, R.; Quader, S., (2022), "Selective targeting of neurons using nanomedicine-based strategies: Open questions and new opportunities", Nanomedicine, vol. 17, No. 8, pp. 495-498, ISSN: 1743-5889.
- Brugniaux, J.; Rodriguez-Rodriguez, R.; Dabiri, A.; Kılıç, K.; Wilson, C.; Goltsov, A.; Colantuoni, A., (2022), "Editorial: Methods and applications in vascular physiology: 2021", Frontiers in Physiology, vol. 13, ISSN: 1664-042X.
- Miralpeix, C.; Reguera, AC.; Fosch, A.; Zagmutt, S.; Casals, N; Cota, D.; Rodriguez-Rodriguez, R., (2021), "Hypothalamic endocannabinoids in obesity: an old story with new challenges", Cellular and molecular life sciences, vol. 78, No. 23, pp. 7469-7490, ISSN: 1420-682X.
- Samper-Martín, B.; Sarrias, A.; Lázaro, B.; Perez-Montero, M.; Rodriguez-Rodriguez, R.; Ribeiro, MP; Banon, A.; Wolfgeher, D.; Jessen, H.J.; Alsina, B.; Clotet, J.; Kron, S.; Saiardi, A.; Jiménez, J.; Bru, S., (2021), "Polyphosphate degradation by Nudt3-Zn2+ mediates oxidative stress response", Cell Reports, vol. 37, No. 7, ISSN: 2211-1247.
- Paraiso, W.; Garcia, J.; Ariza, J.; Zagmutt, S.; Fukushima, S.; Garcia, J.; Mochida, Y.; Serra, D.; Herrero, L.; Kinoh, H.; Casals, N; Kataoka, K.; Rodriguez-Rodriguez, R.; Quader, S., (2021), "Poly-ion complex micelles effectively deliver CoA-conjugated CPT1A inhibitors to modulate lipid metabolism in brain cells", Biomaterials science, vol. 9, No. 21, pp. 7076-7091, ISSN: 2047-4830.
- Fosch, A.; Zagmutt, S.; Casals, N; Rodriguez-Rodriguez, R., (2021), "New insights of sf1 neurons in hypothalamic regulation of obesity and diabetes", International Journal of Molecular Sciences, vol. 22, No. 12, ISSN: 1422-0067.
- Paraiso, W.; Garcia-Chica, J.; Ariza, X.; Garcia, J.; Kataoka, K.; Rodriguez-Rodriguez, R.; Quader, S., (2021), "A new nanomedicine platform to deliver a carnitine palmitoyl-transferase 1 (CPT1) inhibitor into glioma cells and neurons", Materials Proceedings, vol. 4, No. 1, ISSN: 2673-4605.
- Rodriguez-Rodriguez, R.; Miralpeix, C., (2021), "Hypothalamic Regulation of Obesity", International Journal of Molecular Sciences, vol. 22, No. 24, ISSN: 1422-0067.
- Miralpeix, C.; Reguera, AC.; Fosch, A.; Casas, M.; Lillo, J.; Navarro, G.; Franco, R.; Casas, J.; Alexander, S.P.H.; Casals, N; Rodriguez-Rodriguez, R., (2021), "Carnitine palmitoyltransferase 1C negatively regulates the endocannabinoid hydrolase ABHD6 in mice, depending on nutritional status", British journal of pharmacology, vol. 178, No. 7, pp. 1507-1523, ISSN: 0007-1188.
- Ferrer-Vilanova, A.; Alonso, Y.; Dietvorst, J.; Pérez-Montero, M.; Rodriguez-Rodriguez, R.; Ivanova, K.; Tzanov, T.; Vigues, N.; Mas, J.; Guirado, G.; Munoz-Berbel, X., (2021), "Sonochemical coating of Prussian Blue for the production of smart bacterial-sensing hospital textiles", Ultrasonics sonochemistry, vol. 70, ISSN: 1350-4177.
- Fadó, R.; Rodriguez-Rodriguez, R.; Casals, N, (2021), "The return of malonyl-CoA to the brain: Cognition and other stories", Progress in lipid research, vol. 81, ISSN: 0163-7827.
- Yoneshiro, T.; Rodriguez-Rodriguez, R.; Betz, M.; Rensen, PCN, (2020), "Editorial: Current Challenges for Targeting Brown Fat Thermogenesis to Combat Obesity", Frontiers in Endocrinology, vol. 11, ISSN: 1664-2392.
- Barroso, E.; Rodriguez-Rodriguez, R.; Zarei, M.; Pizarro-Delgado, J.; Planvila, A.; Palomer, X.; Villarroya, F.; Vazquez-Carrera, M., (2020), "SIRT3 deficiency exacerbates fatty liver by attenuating the HIF1 alpha-LIPIN 1 pathway and increasing CD36 through Nrf2", Cell communication and signaling, vol. 18, No. 1, ISSN: 1478-811X.
- Garcia-Chica, J.; Paraiso, W.; Tanabe, S.; Serra, D.; Herrero, L.; Casals, N; Garcia, J.; Ariza, X.; Quader, S.; Rodriguez-Rodriguez, R., (2020), "An overview of nanomedicines for neuron targeting", Nanomedicine, vol. 15, No. 16, pp. 1617-1636, ISSN: 1743-5889.
- Muley, H.; Fadó, R.; Rodriguez-Rodriguez, R.; Casals, N, (2020), "Drug uptake-based chemoresistance in breast cancer treatment", Biochemica pharmacology, vol. 177, ISSN: 0006-2952.
- Claro-Cala, C.; Quintela, J.; Perez-Montero, M.; Miñano, J.; Alvarez de Sotomayor, M.; Herrera, M.; Rodriguez-Rodriguez, R., (2020), "Pomace olive oil concentrated in triterpenic acids restores vascular function, glucose tolerance and obesity progression in mice", Nutrients, vol. 12, No. 2, ISSN: 2072-6643.
- Gimenez-Gomez, P.; Rodriguez-Rodriguez, R.; Rios, J.; Perez-Montero, M.; Gonzalez, E.; Gutierrez-Capitan, M.; Plaza, Jose A; Munoz-Berbel, X.; Jimenez-Jorquera, C., (2020), "A self-calibrating and multiplexed electrochemical lab-on-a-chip for cell culture analysis and high-resolution imaging", Lab on a chip, ISSN: 1473-0197.
- Rodriguez-Rodriguez, R.; Ackermann, T. N.; Plaza, Jose A; Simonsen, Ulf; Matchkov, V.; Llobera, A.; Muñoz-Berbel, X., (2019), "Ultrasensitive photonic microsystem enabling sub-micrometric monitoring of arterial oscillations for advanced cardiovascular studies", Frontiers in Physiology, vol. 10, ISSN: 1664-042X.
- Miralpeix, C.; Fosch, A.; Casas, J.; Baena, M.; Herrero, L.; Serra, D.; Rodriguez-Rodriguez, R.; Casals, N, (2019), "Hypothalamic endocannabinoids inversely correlate with the development of diet-induced obesity in male and female mice", Journal of lipid research, vol. 60, No. 7, pp. 1260-1269, ISSN: 0022-2275.
- Márquez, A.; Aymerich, J.; Dei, M.; Rodriguez-Rodriguez, R.; Vázquez-Carrera, M.; Pizarro-Delgado, J.; Giménez-Gómez, P.; Merlos, Á.; Terés, L.; Serra-Graells, F.; Jiménez-Jorquera, C.; Domínguez-Horna, C.; Muñoz-Berbel, X., (2019), "Reconfigurable multiplexed point of Care System for monitoring type 1 diabetes patients", Biosensors and bioelectronics, vol. 136, pp. 38-46, ISSN: 0956-5663.
- Rodriguez-Rodriguez, R.; Miralpeix, C.; Fosch, A.; Pozo Ariza, M; Calderón Domínguez, M.; Perpinyà, X.; Vellvehi, M.; López, M.; Herrero, L.; Serra, D.; Casals, N, (2019), "CPT1C in the ventromedial nucleus of the hypothalamus is necessary for brown fat thermogenesis activation in obesity", Molecular Metabolism, vol. 19, pp. 75-85, ISSN: 2212-8778.
- Sandoval, V.; Rodriguez-Rodriguez, R.; Martinez-Garza, U.; Rosell-Cardona, C.; Lamuela Raventos, R.; Marrero, P.; Haro, D.; Relat, J., (2018), "Mediterranean Tomato-Based Sofrito Sauce Improves Fibroblast Growth Factor 21 (FGF21) Signaling in White Adipose Tissue of Obese Zucker Rats", Molecular nutrition and food research, vol. 62, No. 4, ISSN: 1613-4125.
- Hofmann, K.; Rodriguez-Rodriguez, R.; Gaebler, A.; Casals, N; Scheller, A.; Kuerschner, L., (2017), "Astrocytes and oligodendrocytes in grey and white matter regions of the brain metabolize fatty acids", Scientific Reports, vol. 7, ISSN: 2045-2322.
- Rodriguez-Rodriguez, R.; Jimenez-Altayo, F.; Alsina, L.; Onetti, Y.; Rinaldi de Alvarenga, J.; Claro, C.; Ogalla, E.; Casals, N; Lamuela Raventos, R., (2017), "Mediterranean tomato-based sofrito protects against vascular alterations in obese Zucker rats by preserving NO bioavailability", Molecular nutrition and food research, vol. 61, No. 9, ISSN: 1613-4125.
- Pozo Ariza, M; Rodriguez-Rodriguez, R.; Ramírez, S.; Seoane Collazo, P.; López, M.; Serra, D.; Herrero, L.; Casals, N, (2017), "Hypothalamic regulation of liver and muscle nutrient partitioning by brain-specific carnitine palmitoyltransferase 1C (CPT1C) in male mice", Endocrinology, ISSN: 1945-7170.
- de Pedro, S.; Muñoz, X.; Rodriguez-Rodriguez, R.; Sort, J.; Plaza, J.; Brugger, J.; Llobera, A.; Cadarso, V., (2016), "Characterization of Ferrofluid-Based Stimuli-Responsive Elastomers", Frontiers in Mechanical Engineering, vol. 2, No. 12, ISSN: 2297-3079.
- Gimenez-Gomez, P.; Rodriguez-Rodriguez, R.; Muñoz-Berbel, X.; Rios, J.; Gonzalez, E.; Plaza, Jose A; Jiménez-Jorquera, C., (2016), "Silicon-glass LoC for reliable multi-parametric cell culture monitoring and advanced imaging", International Conference on Miniaturized Systems for Chemistry and Life Sciences, ISSN: 978-097980649-0.
- Justo, M.; Claro, C.; Zeyda, M.; Stulnig, T.; Herrera, M.; Rodriguez-Rodriguez, R., (2016), "Rice bran prevents high-fat diet-induced inflammation and macrophage content in adipose tissue", European Journal of Nutrition-esborrar, vol. 55, No. 6, pp. 2011-2019, ISSN: 1436-6207.
- Perez-Ternero, C.; Rodriguez-Rodriguez, R.; Herrera, M.; Alvarez de Sotomayor, M., (2016), "Diet supplementation with rice bran enzymatic extract restores endothelial impairment and wall remodelling of ApoE-/- mice microvessels", Atherosclerosis, vol. 250, pp. 15-22, ISSN: 0021-9150.
- Alonso, A.; Vigues, N.; Rodriguez-Rodriguez, R.; Borrisé, X.; Muñoz, M.; Muraviev, D.; Mas, J.; Muñoz-Berbel, X., (2016), "Self-oriented Ag-based polycrystalline cubic nanostructures through polymer stabilization", Nanotechnology, ISSN: 0957-4484.
- Casals, N; Zammit, V.; Herrero, L.; Fadó, R.; Rodriguez-Rodriguez, R.; Serra, D., (2016), "Carnitine palmitoyltransferase 1C: From cognition to cancer", Progress in lipid research, vol. 61, pp. 134-148, ISSN: 0163-7827.
- Alonso, A.; Vigues, N.; Rodriguez-Rodriguez, R.; Borrisé, X.; Muñoz, M.; Muraviev, D.; Mas, J.; Muñoz-Berbel, X., (2015), "Activity-tunable nanocomposites based on dissolution and in situ recrystallization of nanoparticles on ion exchange resins", RSC Advances, vol. 109, No. 5, pp. 89971-89975, ISSN: 2046-2069.
- Barroso, E.; Rodriguez-Rodriguez, R.; Chacon, M R.; Maymó-Masip, E.; Ferrer, L.; Salvado, L.; Salmeron, E.; Wabistch, M.; Palomer, X.; Vendrell, J.; Wahli, W.; Vazquez-Carrera, M., (2015), "PPARβ/δ ameliorates fructose-induced insulin resistance in adipocytes by preventing Nrf2 activation", Biochimica et biophysica acta. Molecular basis of disease, vol. 1852, No. 5, pp. 1049-1058, ISSN: 0925-4439.
- Claro, C.; Ogalla, E.; Rodriguez-Rodriguez, R.; Herrera, M.; Alvarez de Sotomayor, M., (2015), "Phenolic content of extra virgin olive oil is essential to restore endothelial dysfunction but not to prevent vascular inflammation in atherosclerotic lesions of Apo E deficient mice", Journal of functional foods, vol. 15, pp. 126-136, ISSN: 1756-4646.
- Rodriguez-Rodriguez, R., (2015), "Oleanolic Acid and Related Triterpenoids from Olives on Vascular Function: Molecular Mechanisms and Therapeutic Perspectives", Current medicinal chemistry, vol. 22, No. 11, pp. 1414-1425, ISSN: 0929-8673.
- Ogalla, E.; Claro, C.; Alvarez de Sotomayor, M.; Herrera, M.; Rodriguez-Rodriguez, R., (2015), "Structural, mechanical and myogenic properties of small mesenteric arteries from ApoE KO mice: Characterization and effects of virgin olive oil diets", Atherosclerosis, vol. 238, No. 1, pp. 55-63, ISSN: 0021-9150.
- Justo, M.; Claro, C.; Vila, E.; Herrera, M.; Rodriguez-Rodriguez, R., (2014), "Microvascular disorders in obese Zucker rats are restored by a Rice bran diet", Nutrition metabolism and cardiovascular diseases, vol. 24, No. 5, pp. 524-531, ISSN: 0939-4753.
- Candiracci, M.; Justo, M.; Castaño, A.; Rodriguez-Rodriguez, R.; Herrera, M., (2014), "Rice Bran Enzymatic Extract-supplemented diets modulate adipose tissue inflammation markers in Zucker rats", Nutrition, vol. 30, No. 4, pp. 466-472, ISSN: 0899-9007.
- Perez-Ternero, C.; Rodriguez-Rodriguez, R.; Parrado, J.; Alvarez de Sotomayor, M., (2013), "Grape pomace enzymatic extract restores vascular dysfunction evoked by endothelin-1 and DETCA via NADPH oxidase downregulation and SOD activation", Journal of functional foods, vol. 5, pp. 1673-1683, ISSN: 1756-4646.
- Muñoz-Berbel, X.; Rodriguez-Rodriguez, R.; Vigués, N.; Mas, J.; Verpoorte, E.; Llobera, A., (2013), "Monolithically integrated biophotonic lab-on-a-chip for cell culture and simultaneous pH monitoring", Lab on a chip, pp. 4239-4247, ISSN: 1473-0197.
- Justo, M.; Candiracci, M.; Dantas, A.; Vila, E.; Herrera, M.; Rodriguez-Rodriguez, R., (2013), "Rice bran enzymatic extract restores endothelial function and vascular contractility in obese rats by reducing vascular inflammation and oxidative stress", Journal of nutritional biochemistry, vol. 24, pp. 1453-1461, ISSN: 0955-2863.
- Alonso, A.; Vigues, N.; Muñoz-Berbel, X.; Rodriguez-Rodriguez, R.; Mas, J.; Muraviev, D., (2013), "Superparamagnetic Ag@Co-nanocomposites on granulated cation exchange polymeric matrices with enhanced antibacterial activity for the environmentally safe purification of water", Advanced functional materials, vol. 23, No. 19, pp. 2450-2458, ISSN: 1616-301X.
- Barroso, E.; Del Valle, J.; Porquet, D.; Vieira Santos, A.; Salvado, L.; Rodriguez-Rodriguez, R.; Gutierrez, P.; Anglada-Huguet, M.; Alberch, J.; Camins, A.; Palomer, X.; Pallas, M.; Michalik, L.; Wahli, W.; Vazquez-Carrera, M., (2013), "Tau hyperphosphorylation and increased BACE1 and RAGE levels in the cortex of PPARb/g-null mice", Biochimica et biophysica acta. Molecular basis of disease, vol. 1832, No. 8, pp. 1241-1248, ISSN: 0925-4439.
- Justo, M.; Rodriguez-Rodriguez, R.; Claro, C.; Alvarez de Sotomayor, M.; Parrado, J.; Herrera, M., (2013), "Water-soluble rice bran enzymatic extract attenuates dyslipidemia, hypertension and insulin resistance in obese Zucker rats", European journal of nutrition, vol. 52, No. 2, pp. 789-797, ISSN: 1436-6207.
- Rodriguez-Rodriguez, R.; Justo, M.; Claro, C.; Vila, E.; Parrado, J.; Herrera, M.; Alvarez de Sotomayor, M., (2012), "Endothelium-dependent vasodilator and antioxidant properties of a novel enzymatic extract of grape pomace from wine industrial waste", Food chemistry, vol. 135, No. 3, pp. 1044-1051, ISSN: 0308-8146.
- Rodriguez-Rodriguez, R.; Simonsen, Ulf, (2012), "Measurement of nitric oxide and reactive oxygen species in the vascular wall", Current analytical chemistry, vol. 8, No. 4, pp. 485-494, ISSN: 1573-4110.
- Rodriguez-Rodriguez, R.; Muñoz-Berbel, X.; Demming, S.; Buttgenbach, S.; Herrera, M.; Llobera, A., (2012), "Cell-based microfluidic device for screening anti-proliferative activity of drugs in vascular smooth muscle cells", Biomedical microdevices, vol. 14, No. 6, pp. 1129-1140, ISSN: 1387-2176.
- Alonso, A.; Muñoz-Berbel, X.; Vigues, N.; Rodriguez-Rodriguez, R.; Macanás, J.; Mas, J.; Muñoz, M.; Muraviev, D., (2012), "Intermatrix synthesis of monometallic and magnetic metal/metal oxide nanoparticles with bactericidal activity on anionic exchange polymers", RSC Advances, vol. 11, No. 2, pp. 4596-4599, ISSN: 2046-2069.
- Buus, N.; Rodriguez-Rodriguez, R.; Hansson, N.; Stankevicious, E.; Andersen, M.; Simonsen, Ulf, (2011), "Antiatherogenic effects of oleanolic acid in apolipoprotein e knockout mice", European journal of pharmacology, vol. 670, pp. 519-526, ISSN: 0014-2999.
- Mingorance, C.; Rodriguez-Rodriguez, R.; Justo, M.; Alvarez de Sotomayor, M.; Herrera, M., (2011), "Critical update for the clinical use of L-carnitine analogs in cardiometabolic disorders", Vascular health and risk management (Online), vol. 7, No. 1, pp. 169-176, ISSN: 1178-2048.
- Mingorance, C.; Rodriguez-Rodriguez, R.; Justo, M.; Herrera, M.; Alvarez de Sotomayor, M., (2011), "Pharmacological effects and clinical applications of propionyl-L-carnitine", Nutrition reviews, vol. 69, pp. 279-290, ISSN: 0029-6643.
- Herrera, M.; Mingorance, C.; Rodriguez-Rodriguez, R.; Alvarez de Sotomayor, M., (2010), "Endothelial dysfunction and aging: An update", Ageing research reviews, vol. 9, No. 2, pp. 142-152, ISSN: 1568-1637.
- Simonsen, Ulf; Rodriguez-Rodriguez, R.; Daalsgard, T.; Buus, N.; Stankevicious, E., (2009), "Novel approaches to improving endothelium-dependent nitric oxide-mediated vasodilatation", Pharmacological reports, vol. 61, No. 1, pp. 105-115, ISSN: 1734-1140.
- Rodriguez-Rodriguez, R.; Herrera, M.; Alvarez de Sotomayor, M.; Ruiz-Gutierrez, V., (2009), "Effects of pomace olive oil-enriched diets on endothelial function of small mesenteric arteries from spontaneously hypertensive rats", British journal of nutrition, vol. 102, No. 10, pp. 1435-1444, ISSN: 0007-1145.
- Rodriguez-Rodriguez, R.; Yarova, P.; Winter, P.; Dora, K., (2009), "Desensitization of endothelial P2Y1 receptors by PKC-dependent mechanisms in pressurized rat small mesenteric arteries", British journal of pharmacology, vol. 158, No. 6, pp. 1609-1620, ISSN: 0007-1188.
- Rodriguez-Rodriguez, R.; Stankevicious, E.; Herrera, M.; Ostergaard, L.; Andersen, M.; Ruiz-Gutierrez, V.; Simonsen, Ulf, (2008), "Oleanolic acid induces relaxation and calcium-independent release of endothelium-derived nitric oxide", British journal of pharmacology, vol. 155, No. 4, pp. 535-546, ISSN: 0007-1188.
- Martinez-Gonzalez, J.; Rodriguez-Rodriguez, R.; Gonzalez-Diez, M.; Rodriguez, C.; Herrera, M.; Ruiz-Gutierrez, V.; Badimón, L., (2008), "Oleanolic acid induces prostacyclin release in human vascular smooth muscle cells through a cyclooxygenase-2-dependent mechanism", Journal of nutrition, vol. 138, No. 3, pp. 443-448, ISSN: 0022-3166.
- Alvarez de Sotomayor, M.; Mingorance, C.; Rodriguez-Rodriguez, R.; Marhuenda, E.; Herrera, M., (2007), "L-carnitine and its propionate: Improvement of endothelial function in SHR through superoxide dismutase-dependent mechanisms", Free radical research, vol. 41, No. 8, pp. 884-891, ISSN: 1071-5762.
- Rodriguez-Rodriguez, R.; Herrera, M.; Alvarez de Sotomayor, M.; Ruiz-Gutierrez, V., (2007), "Pomace Olive Oil Improves Endothelial Function in Spontaneously Hypertensive Rats by Increasing Endothelial Nitric Oxide Synthase Expression", American journal of hypertension, vol. 20, No. 7, pp. 728-724, ISSN: 0895-7061.
- Rodriguez-Rodriguez, R.; Sanchez-Perona, J.; Herrera, M.; Ruiz-Gutierrez, V., (2006), "Triterpenic compounds from "Orujo" olive oil elicit vasorelaxation in aorta from spontaneously hypertensive rats", Journal of agricultural and food chemistry, vol. 54, No. 6, pp. 2096-2102, ISSN: 0021-8561.
- Herrera, M.; Rodriguez-Rodriguez, R.; Ruiz-Gutierrez, V., (2006), "Functional properties of pentacyclic triterpenes contained in "orujo" olive oil", Current nutrition and food science, vol. 2, No. 1, pp. 45-49, ISSN: 1573-4013.
- Sanchez-Perona, J.; Rodriguez-Rodriguez, R.; Ruiz-Gutierrez, V., (2005), "Effects of oleic acid rich oils on aorta lipids and lipoprotein lipase activity of spontaneously hypertensive rats", Journal of agricultural and food chemistry, vol. 53, No. 18, pp. 7330-7336, ISSN: 0021-8561.
- Rodriguez-Rodriguez, R.; Herrera, M.; Sanchez-Perona, J.; Ruiz-Gutierrez, V., (2004), "Potential vasorelaxant effects of oleanolic acid and erythrodiol, two triterpenoids contained in 'orujo' olive oil, on rat aorta", British journal of nutrition, vol. 92, No. 4, pp. 635-642, ISSN: 0007-1145.
Capítulos de libro
- Rodriguez-Rodriguez, R.; Simonsen, Ulf, (01/04/2014), "Natural triterpenoids from olive oil: Potential activities against cancer", Natural Compounds as Inducers of Cell Death, pp. 447-461. ISBN: 978-940074575-9.
- Rodriguez-Rodriguez, R.; Ruiz-Gutierrez, V., (01/01/2010), "Functional Properties of Pentacyclic Triterpenes Contained in Pomace Olive Oil", Olives and Olive Oil in Health and Disease Prevention, pp. 1431-1438. ISBN: 978-012374420-3.
- Rodriguez-Rodriguez, R.; Ruiz-Gutierrez, V., (01/01/2010), "Vasorelaxant Effects of Oleanolic Acid and Erythrodiol in Pomace Olive Oil", Olives and Olive Oil in Health and Disease Prevention, pp. 813-820. ISBN: 978-012374420-3.
- Rodriguez-Rodriguez, R.; Ruiz-Gutierrez, V., (01/01/2009), "Minor components from olive oil: their most promising biological activities", Advances in Olive Resources, pp. 79-104. ISBN: 978-81-7895-388-5.
Proyectos de investigación
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EXPLORANDO LA RELEVANCIA DE LA INTERACCION DE CPT1C CON OTRAS PROTEINAS EN LA REGULACION DE LA HOMEOSTASIS ENERGETICA Y EL DESARROLLO DE LA OBESIDAD01/09/2021 - 31/08/2024IP: Casals, N; Rodriguez-Rodriguez, R.
Ministerio de Ciencia e Innovación (MICINN)
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Administracion de fármacos específicos de la CPT1 central: una novedosa estrategia basada en nanomedicina para combatir obesidad y cáncer01/01/2019 - 31/12/2021IP: Rodriguez-Rodriguez, R.
MINISTERIO DE CIENCIA E INNOVACION
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Cpt1c en el hipotálamo ventromedial como nueva diana terapéutica en la regulación del balance energético: mecanismos moleculares implicados01/01/2018 - 31/12/2020IP: Casals, N; Rodriguez-Rodriguez, R.
Ministerio de Economía, Industria y Competitividad
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EFECTO DE LOS POLIFENOLES DE LA DIETA EN LA SENSIBILIDAD A LA INSULINA, MARCADORES DE INFLAMACION Y EN LA INCIDENCIA DE LA DIABETES TIPO II (AGL2016-75329-R)01/01/2017 - 31/12/2020IP: Lamuela Raventos, R.
Ministerio de Economía y Competitividad
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Carnitine palmitoyltransferase 1-mediated strategies to activate brown fat and reduce food intake to fight against obesity01/03/2017 - 01/03/2020IP: Casals, N; Serra, D.
Fundació la Marató de TV3
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Papel de la carnitina pamitoil transferasa 1C como sensor hipotalámico de aciles-CoA y regulador del metabolismo periférico de los lípidos (SAF2014-52223-C2-2-R)01/01/2015 - 31/12/2017IP: Casals, N
Ministerio de Ciencia e Innovación (MICINN)
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Componentes bioactivos del sofrito. Estudio metabolómico y mecanismos implicados en el control de estres oxidativo e inflamación01/01/2014 - 31/12/2016IP: Lamuela Raventos, R.
Ministerio de Economía y Competitividad
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Investigación y desarrollo de nuevas posibilidades de aplicaciones terapéuticas en el aceite de oliva01/11/2010 - 31/12/2013IP: Herrera, M.
Ministerio de Ciencia e Innovación (MICINN)
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Caracterizacion de las propiedades funcionales a nivel cardiovascular y del sindrome metabolico de un extracto enzimatico del salvado de arroz (AGL2009-11559 ALI)01/01/2010 - 31/12/2012IP: Herrera, M.
Ministerio de Ciencia e Innovación (MICINN)
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Estudio de biodisponibilidad de los triterpenos del aceite de orujo y su papel sobre procesos implicados en la formacion de la placa de ateroma (AGL2008-02285 ALI)01/01/2009 - 31/12/2011IP: Ruiz-Gutierrez, V.
Ministerio de Ciencia y Tecnología
Actividades
- NanoBioMed Presentació de comunicació "Development of C75-CoA-loaded polymeric nanomedicines to inhibit CPT1 in specific brain cells", 2020.
- Copenhagen Bioscience Conference- Metabolism in action Presentació de poster "Deciphering the cross-talk relationship between brown fat thermogenesis and hypothalamic endocannabinoid dynamics during obesity development", 2019.
- Gordon Research Conference on Cannabinoid Function in the CNS Presentació de comunicació "CPT1C: a novel regulator of ABHD6 activity", 2019.
- Gordon Research Conference on Cannabinoid Function in the CNS Presentació de poster "The dynamic of endocannabinoids in the hypothalamus during obesity development in male and female mice and its cross-talk to Brown fat thermogenesis", 2019.
- European Atherosclerosis Society Congress Presentació de poster "POMACE OLIVE OIL ENRICHED IN OLEANOLIC ACID IMPROVES DIET-INDUCED OBESITY AND EXERTS PROTECTIVE EFFECTS IN VASCULAR DYSFUNCTION AND METABOLIC PARAMETERS", 2019.
- MetNet Annual Meeting: Targeting Metabolism to Develop New Therapies Presentació de comunicació "Carnitine palmitoyltransferase 1C as the first negative regulator of the endocannabinoids hydrolase ABHD6", 2019.
- EMBO Workshop- Organ crosstalk in energy balance and metabolic disease Presentació de poster "The dynamic of endocannabinoid levels in the hypothalamus negatively correlates with obesity development in male and female mice", 2019.
- Reunión Anual de la Sociedad Española de Investigación sobre Cannabinoides Presentació de poster "CPT1C AS THE FIRST NEGATIVE REGULATOR OF THE ENDOCANNABINOIDS α/β-HYDROLASE CONTAINING 6 (ABHD6)", 2019.
- Congreso de la Sociedad Española de Endocannabinoides Presentació de poster "Analysis of hypothalamic endocannabinoids fluctuations in response to high fat diet in male and female mice", 2017.
- Congreso de la Sociedad Española de Endocannabinoides Presentació de comunicació "ABHD6 and CPT1C interaction as a novel mechanism to regulate thermogenesis", 2017.