Directory
HERNÁNDEZ ORTEGA, Sara
Ext. 5262
Department of Basic Areas
Control del cicle cel.lular per nutrients
HERNÁNDEZ ORTEGA, Sara
CV
Teacher profile
Professor Col.laborador
Basic Areas, DEPARTMENT OF BASIC SCIENCIES. Universitat Internacional de Catalunya
Academic curriculum
- Biologia Molecular Universitat Internacional de Catalunya
- Máster en Biomedicina Universitat de Barcelona
- Licenciada en Biotecnología Universitat de Vic
Professional experience
Universitat Internacional de Catalunya
Professor gen. 2010 - present
Postdoctoral researcher 2014 - 2016
During my Postdoctorate I developed several projects in cancer research that are about to be published. In addition, I taught different PhD students with whom I developed my leadership skills, communication skills and passion for imparting knowledge.
Doctoral student - Oct. 2009 - 2014
I worked in J. Clotet's group doing my PhD in molecular biology researching the cell cycle with S. cerevisiae and also cell cultures. Here I have learned new techniques and developed new skills such as being more self-sufficient and coordinating my own research.
Sant Joan de Déu Foundation graphic. Manager of Innovation Projects
Sant Joan de Déu Foundation 2018 - 2020
Building projects to transform ideas into concepts and impact medical care.
Share4Rare chart. Compartir4Raro project manager Jul. 2018 - ago 2020
PlasmoFAB Chart – PlasmoFAB Tutor Oct. 2017 - December. 2019, Greece
PLASMOFab aims to develop plasmonics compatible with CMOS in a generic planar integration process as a means to consolidate photonic and electronic integration. PLASMOFab will use wafer-scale integration to demonstrate the low cost, volume manufacturing and high performance of powerful PICs. The new integration technology will reveal a series of innovations with profound benefits from the enhanced interaction between light and matter enabled by plasmonics in optical transmitters and biosensors
Professor gen. 2010 - present
Postdoctoral researcher 2014 - 2016
During my Postdoctorate I developed several projects in cancer research that are about to be published. In addition, I taught different PhD students with whom I developed my leadership skills, communication skills and passion for imparting knowledge.
Doctoral student - Oct. 2009 - 2014
I worked in J. Clotet's group doing my PhD in molecular biology researching the cell cycle with S. cerevisiae and also cell cultures. Here I have learned new techniques and developed new skills such as being more self-sufficient and coordinating my own research.
Sant Joan de Déu Foundation graphic. Manager of Innovation Projects
Sant Joan de Déu Foundation 2018 - 2020
Building projects to transform ideas into concepts and impact medical care.
Share4Rare chart. Compartir4Raro project manager Jul. 2018 - ago 2020
PlasmoFAB Chart – PlasmoFAB Tutor Oct. 2017 - December. 2019, Greece
PLASMOFab aims to develop plasmonics compatible with CMOS in a generic planar integration process as a means to consolidate photonic and electronic integration. PLASMOFab will use wafer-scale integration to demonstrate the low cost, volume manufacturing and high performance of powerful PICs. The new integration technology will reveal a series of innovations with profound benefits from the enhanced interaction between light and matter enabled by plasmonics in optical transmitters and biosensors
Publications
Articles
- Quandt, E.; Masip, N.; Hernández-Ortega, S; Sánchez-Botet, A.; Gasa, L.; Fernández, A.; Plutta, S.; Martínez-Láinez, J.; Bru, S.; Munoz, P.; Floor, M.; Villà-Freixa, J.; Morris, M.; Vidal, A.; Villanueva, A.; Clotet, J.; Ribeiro, M., (2023), "CDK6 is activated by the atypical cyclin I to promote E2F-mediated gene expression and cancer cell proliferation", Molecular Oncology, vol. 17, No. 7, pp. 1228-1245, ISSN: 1574-7891.
- Hernández-Ortega, S; Sánchez-Botet, A.; Quandt, E.; Masip, N.; Gasa, L.; Verde, G.; Jiménez, J.; Levin, R.; Rugatanira, F.; Burlingame, A.; Ribeiro, MP; Shokat, K.; Clotet, J., (2019), "Phosphoregulation of the oncogenic protein regulator of cytokinesis 1 (PRC1) by the atypical CDK16/CCNY complex", Experimental and molecular medicine, vol. 51, No. 4, pp. 1-17, ISSN: 1226-3613.
- Sánchez-Botet, A.; Gasa, L.; Quandt, E.; Hernández-Ortega, S; Jiménez, J.; Mezquita, Pau; Carrasco, M.; Kron, S.; Vidal, A.; Villanueva, A.; Ribeiro, MP; Clotet, J., (2018), "The atypical cyclin CNTD2 promotes colon cancer cell proliferation and migration", Scientific Reports, vol. 8, No. 1, ISSN: 2045-2322.
- Bru, S.; Samper-Martín, B.; Quandt, E.; Hernández-Ortega, S; Martínez-Láinez, JM.; Garí, E.; Rafel, M.; Torres-Torronteras, J.; Martí, R.; Ribeiro, MP; Jiménez, J.; Clotet, J., (2017), "Polyphosphate is a key factor for cell survival after DNA damage in eukaryotic cells", DNA repair, vol. 57, pp. 171-178, ISSN: 1568-7864.
- Gasa, L.; Sánchez-Botet, A.; Quandt, E.; Hernández-Ortega, S; Jiménez, J.; Carrasco, M.; Simonetti, S.; Kron, S.; Ribeiro, MP; Nadal, E.; Villanueva, A.; Clotet, J., (2017), "A systematic analysis of orphan cyclins reveals CNTD2 as a new oncogenic driver in lung cancer", Scientific Reports, vol. 7, No. 1, ISSN: 2045-2322.
- Bru, S.; Martínez-Láinez, JM.; Hernández-Ortega, S; Quandt, E.; Jiménez, J.; Clotet, J., (2016), "Polyphosphate is Involved in Cell Cycle Progression and Genomic Stability in Saccharomyces cerevisiae", Molecular microbiology, vol. 101, No. 3, pp. 367-380, ISSN: 0950-382X.
- Hernández-Ortega, S; Bru, S.; Ricco, N.; Ramírez, S.; Casals, N; Jiménez, J.; Isasa, M.; Crosas, B.; Clotet, J., (2013), "Defective in Mitotic Arrest 1 (Dma1) ubiquitin ligase controls G1 cyclin degradation.", The journal of biological chemistry (Versió web), vol. 288, No. 7, pp. 4704-4714, ISSN: 1083-351X.
- Menoyo, S.; Ricco, N.; Bru, S.; Hernández-Ortega, S; Escoté, X.; Aldea, M.; Clotet, J., (2013), "Phosphate-Activated Cyclin-Dependent Kinase Stabilizes G(1) Cyclin To Trigger Cell Cycle Entry", Mol Cell Biol., vol. 33(7), pp. 1273-1284, ISSN: 1098-5549.
- Hernández-Ortega, S, (2012), "RANK induces epithelial-mesenchymal transition and stemness in human mammary epithelial cells and promotes tumorigenesis and metastasis", Cancer research, vol. 72, No. 11, pp. 2879-2888, ISSN: 0008-5472.
Activities
- Cell Bio virtual 2021 Presentació de poster "CDK6 is activated by the atypical cyclin I to promote cancer cell proliferation", 2021.
- Jornades de Biologia Molecular Ponència "Human New Cyclins: expression in tumors and novel interactors", 2015.
- Jornades de Biologia Molecular Ponència "Human New Cyclins: expression in tumors and novel interactors.", 2015.
- Jornades de Biologia Molecular Ponència "G1 cyclins degradation is regulated by different E3 ubiquitin ligases", 2015.
- Jornades de Biologia Molecular Ponència "Polyphosphate is a key factor for the dNTP synthesis", 2014.
- Jornades de Biologia Molecular Ponència "Polyphosphate is a key factor for the dNTP synthesis", 2014.
- Congreso de la Sociedad Española de Bioquímica y Biologia Molecular Presentació de comunicació "Regulación de la actividad ligasa de Dmal en el ciclo celular de S.cerevisae", 2013.
- Congreso de la Sociedad Española de Bioquímica y Biologia Molecular Presentació de comunicació "Nuevo mecanismo de degradación para las ciclinas de G1", 2013.
- Jornades de Biologia Molecular Ponència "Dma1 ubiquitin ligase is cell cycle regulated during G1 phase", 2013.
- JORNADAS DE INTERCAMBIO DE EXPERIENCIAS DE INNIVACIÓN DOCENTE Presentació de comunicació "Proyecto educativo para la armonización y convergencia de los estudios oficiales de posgrado en desarrollo agroforestal", 2007.