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Our teaching and research team
WRIGHT, Roni Helene Grace

WRIGHT, Roni Helene Grace

Professor Col.laborador
DEPARTMENT OF BASIC SCIENCIES
Department of Basic Areas
From cell metabolism to metabolic diseases (METADIS)
  • Academic training
    • Articles
    • Books
  • Subjects taught

Academic training

  • Molecular Biology
  • University of Glasgow

Doctora Phd Molecular Biology and Cancer - UNIVERSITY OF GLASGOW
Llicenciada Bsc (honors) Biochemistry and Immunology - UNIVERSITY OF STRATHCLYDE

Publications

  • Cellular and molecular life sciences, A progesterone derivative linked to a stable phospholipid activates breast cancer cell response without leaving the cell membrane
    Name: Font Mateu, J.; Sanllehí, P.; Sot, J.; Abad, B.; Mateos, N.; Torreno, J.; Ferrari, R.; Wright, R.; Garcia, M.; Joglar, J.; Goñi, F.; Beato, M. Role: Autor Publishing date: 2024
    Vol.: 81 No.: 1
  • INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, CDKN1A/p21 in Breast Cancer: Part of the Problem, or Part of the Solution?
    Name: Manousakis, E.; Martinez, C.; Guimerà, M.; Wright, R. Role: Autor Publishing date: 2023
    Vol.: 24 No.: 24
    DOI: https://dx.doi.org/10.3390/ijms242417488 ISSN or title: 1661-6596
  • Cancer research, Combinatorial treatment with PARP and MAPK inhibitors overcomes phenotype switch-driven drug resistance in advanced melanoma
    Name: Ferretti, L.; Böhi, F.; Leslie, D.; Cheng, P.; Ferrari, E.; Baumgaertner, P.; Alvarado, A.; Sella, F.; Cereghetti, A.; Turko, P.; Wright, R.; De Bock, K.; Speiser, D.; Ferrari, R.; Levesque, M.; Hottiger, M. Role: Autor Publishing date: 2023
    Start page: 3974 End page: 3988 Vol.: 83 No.: 23
  • Cell Reports, The ADP-ribose hydrolase NUDT5 is important for DNA repair
    Name: Wright, R. Role: Autor Publishing date: 2022
    Vol.: 41 No.: 12
  • Frontiers in Endocrinology, Global signalling network analysis of luminal T47D breast cancer cells in response to progesterone
    Name: Wright, R. Role: Autor Publishing date: 2022
    Start page: 1 End page: 19 Vol.: 13 No.: 19
  • Iscience, MyoD induces ARTD1 and nucleoplasmic poly-ADP-ribosylation during fibroblast to myoblast trans-differentiation
    Name: Bisceglie, L.; Hopp, A.-K.; Gunasekera, K.; Wright, R.; Le Dily, F.; Vidal, E.; Dall’Agnese, A.; Caputo, L.; Nicoletti, C.; Puri, P.L.; Beato, M.; Hottiger, M. Role: Autor Publishing date: 2021
    Vol.: 24 No.: 5
  • INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, Role of the nudt enzymes in breast cancer
    Name: Wright, R.; Beato, M. Role: Autor Publishing date: 2021
    Start page: 1 End page: 14 Vol.: 22 No.: 5
    DOI: https://dx.doi.org/10.3390/ijms22052267 ISSN or title: 1661-6596
  • Journal of molecular endocrinology, 90 YEARS OF PROGESTERONE: Molecular mechanisms of progesterone receptor action on the breast cancer genome
    Name: Beato, M.; Wright, R.; Le Dily, F. Role: Autor Publishing date: 2020
    Start page: T65 End page: T79 Vol.: 65 No.: 1
    DOI: https://dx.doi.org/10.1530/JME-19-0266 ISSN or title: 0952-5041
  • CANCERS, Expression of oncogenic drivers in 3D cell culture depends on nuclear ATP synthesis by NUDT5
    Name: Pickup, K.E.; Pardow, F.; Carbonell, J.; Lioutas, A.; Villanueva, J.; Wright, R.; Beato, M. Role: Autor Publishing date: 2019
    Vol.: 11 No.: 9
    DOI: https://dx.doi.org/10.3390/cancers11091337 ISSN or title: 2072-6694
  • Trends in biochemical sciences, ATP, Mg2+, Nuclear Phase Separation, and Genome Accessibility
    Name: Wright, R.; Le Dily, F.; Beato, M. Role: Autor Publishing date: 2019
    Start page: 565 End page: 574 Vol.: 44 No.: 7
  • Molecular cell, Arginine Citrullination at the C-Terminal Domain Controls RNA Polymerase II Transcription
    Name: Sharma, P.; Lioutas, A.; Fernández-Fuentes, N.; Quílez, J.; Carbonell, J.; Wright, R.; Di Vona, C.; Le Dily, F.; Schueller, R.; Eick, D.; Oliva, B.; Beato, M. Role: Autor Publishing date: 2019
    Vol.: 73 No.: 1
  • Genome research, Hormone-control regions mediate steroid receptor–dependent genome organization
    Name: Le Dily, F.; Vidal, E.; Cuartero, Y.; Quílez, J.; Nacht, A.; Vicent, G.; Carbonell, J.; Sharma, P.; Villanueva, J.; Ferrari, R.; de Llobet, L.; Verde, G.; Wright, R.; Beato, M. Role: Autor Publishing date: 2019
    Start page: 29 End page: 39 Vol.: 29 No.: 1
    DOI: https://dx.doi.org/10.1101/gr.243824.118 ISSN or title: 1088-9051
  • CANCERS, Unliganded Progesterone Receptor Governs Estrogen Receptor Gene Expression by Regulating DNA Methylation in Breast Cancer Cells
    Name: Verde, G.; de Llobet, L.; Wright, R.; Quílez, J.; Peiró, S.; Le Dily, F.; Beato, M. Role: Autor Publishing date: 2018
    Vol.: 10 No.: 10
    DOI: https://dx.doi.org/10.3390/cancers10100371 ISSN or title: 2072-6694
  • Nature communications, Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells
    Name: Page, B.D.G.; Valerie, N.C.K.; Wright, R.; Wallner, O.; Isaksson, R.; Carter, M.; Rudd, S.G.; Jemth, A.S.; Almlof, I.; Font-Mateu, J.; Llona-Minguez, S.; Baranczewski, P.; Jeppsson, F.; Homan, E.; Almqvist, H.; Axelsson, H.; Regmi, S.; Gustavsson, A.; Lundback, T.; Scobie, M.; Stromberg, K.; Stenmark, P.; Beato, M.; Helleday, T. Role: Autor Publishing date: 2018
    Vol.: 9
  • Nucleus-Austin, Insight into the machinery that oils chromatin dynamics
    Name: Wright, R.; Fernández-Fuentes, N.; Oliva, B.; Beato, M. Role: Autor Publishing date: 2016
    Start page: 532 End page: 539 Vol.: 7 No.: 6
  • Embo journal, Hormone-induced repression of genes requires BRG1-mediated H1.2 deposition at target promoters
    Name: Nacht, A. S.; Pohl, A.; Zaurin, R.; Soronellas, D.; Quílez, J.; Sharma, P.; Wright, R.; Beato, M.; Vicent, G. Role: Autor Publishing date: 2016
    Start page: 1822 End page: 1843 Vol.: 35 No.: 16
    ISSN or title: 0261-4189
  • Science, ADP-ribose-derived nuclear ATP synthesis by NUDIX5 is required for chromatin remodeling
    Name: Wright, R.; Lioutas, A.; Le Dily, F.; Soronellas, D.; Pohl, A.; Bonet, J.; Nacht, A. S.; Samino, S.; Font-Mateu, J.; Vicent, Guillermo P.; Wierer, M.; Trabado, M.A.; Schelhorn, C.; Carolis, C.; Macias, M.J.; Yanes, O.; Oliva, B.; Beato, M. Role: Autor Publishing date: 2016
    Start page: 1221 End page: 1225 Vol.: 352 No.: 6290
    DOI: https://dx.doi.org/10.1126/science.aad9335 ISSN or title: 0036-8075
  • Biochimica et Biophysica Acta-Gene Regulatory Mechanisms, Linker histones in hormonal gene regulation
    Name: Vicent, G.; Wright, R.; Beato, M. Role: Autor Publishing date: 2016
    Start page: 520 End page: 525 Vol.: 1859 No.: 3
  • Cell research, DNA damage and gene transcription: accident or necessity?
    Name: Beato, M.; Wright, R.; Vicent, Guillermo P. Role: Autor Publishing date: 2015
    Start page: 769 End page: 770 Vol.: 25 No.: 7
    DOI: https://dx.doi.org/10.1038/cr.2015.71 ISSN or title: 1001-0602
  • Genes and development, Distinct structural transitions of chromatin topological domains correlate with coordinated hormone-induced gene regulation
    Name: Le Dily, F.; Bau, D.; Pohl, A.; Vicent, G.; Serra, F.; Soronellas, D.; Castellano, G.; Wright, R.; Ballare, C.; Filion, G.; Marti-Renom, M.; Beato, M. Role: Autor Publishing date: 2014
    Start page: 2151 End page: 2162 Vol.: 28 No.: 19
    DOI: https://dx.doi.org/10.1101/gad.241422.114 ISSN or title: 0890-9369
  • Cell cycle, PARty promoters Hormone-dependent gene regulation requires CDK2 activation of PARP1
    Name: Wright, R.; Beato, M. Role: Autor Publishing date: 2012
    Start page: 4291 End page: 4293 Vol.: 11 No.: 23
    DOI: https://dx.doi.org/10.4161/cc.22531 ISSN or title: 1538-4101
  • Genes and development, CDK2-dependent activation of PARP-1 is required for hormonal gene regulation in breast cancer cells
    Name: Wright, R.; Castellano, G.; Bonet, J.; Le Dily, F.; Font Mateu, J.; Ballare, C.; Nacht, S.; Soronellas, D.; Oliva, B.; Beato, M. Role: Autor Publishing date: 2012
    Start page: 1972 End page: 1983 Vol.: 26 No.: 17
    DOI: https://dx.doi.org/10.1101/gad.193193.112 ISSN or title: 0890-9369

Publications

  • Progesterone Signaling to Chromatin in Breast Cancer Cells. Two Initial Cycles of Remodeling
    Publishing date: 2012 Doi: 10.1007/978-1-4614-1764-4_2 Isbn: 978-1-4614-1764-4

Subjects taught

Course 2024-2025 - Period: 01/09/2024 - 31/08/2025
  • Bachelor’s Degree
    Bachelor's Degree in Dentistry
    • - Human Biology 1
    • - Human Biology 2
Course 2023-2024 - Period: 01/09/2023 - 31/08/2024
  • Bachelor’s Degree
    Bachelor's Degree in Dentistry
    • - Human Biology 1
    • - Human Biology 2
Course 2022-2023 - Period: 01/09/2022 - 31/08/2023
  • Bachelor’s Degree
    Bachelor's Degree in Biomedical Sciences
    • - Cancer Biology
    Bachelor's Degree in Dentistry
    • - Microbiology and Immunology
    • - Human Biology 2
    • - Human Biology 1
Course 2021-2022 - Period: 01/09/2021 - 31/08/2022
  • Bachelor’s Degree
    Bachelor's Degree in Dentistry
    • - Human Biology 2
    • - Microbiology and Immunology
Course 2020-2021 - Period: 01/09/2020 - 31/08/2021
  • Bachelor’s Degree
    Bachelor's Degree in Dentistry
    • - Microbiology and Immunology
Course 2019-2020 - Period: 01/09/2019 - 31/08/2020
  • Bachelor’s Degree
    Bachelor's Degree in Dentistry
    • - Microbiology and Immunology
Course 2018-2019 - Period: 01/09/2018 - 31/08/2019
  • Bachelor’s Degree
    Bachelor's Degree in Dentistry
    • - Microbiology and Immunology

Academic training

  • Molecular Biology
  • University of Glasgow

Doctora Phd Molecular Biology and Cancer - UNIVERSITY OF GLASGOW
Llicenciada Bsc (honors) Biochemistry and Immunology - UNIVERSITY OF STRATHCLYDE

Articles

Books

  • Cellular and molecular life sciences, A progesterone derivative linked to a stable phospholipid activates breast cancer cell response without leaving the cell membrane
    Name: Font Mateu, J.; Sanllehí, P.; Sot, J.; Abad, B.; Mateos, N.; Torreno, J.; Ferrari, R.; Wright, R.; Garcia, M.; Joglar, J.; Goñi, F.; Beato, M. Role: Autor Publishing date: 2024
    Vol.: 81 No.: 1
  • INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, CDKN1A/p21 in Breast Cancer: Part of the Problem, or Part of the Solution?
    Name: Manousakis, E.; Martinez, C.; Guimerà, M.; Wright, R. Role: Autor Publishing date: 2023
    Vol.: 24 No.: 24
    DOI: https://dx.doi.org/10.3390/ijms242417488 ISSN or title: 1661-6596
  • Cancer research, Combinatorial treatment with PARP and MAPK inhibitors overcomes phenotype switch-driven drug resistance in advanced melanoma
    Name: Ferretti, L.; Böhi, F.; Leslie, D.; Cheng, P.; Ferrari, E.; Baumgaertner, P.; Alvarado, A.; Sella, F.; Cereghetti, A.; Turko, P.; Wright, R.; De Bock, K.; Speiser, D.; Ferrari, R.; Levesque, M.; Hottiger, M. Role: Autor Publishing date: 2023
    Start page: 3974 End page: 3988 Vol.: 83 No.: 23
  • Cell Reports, The ADP-ribose hydrolase NUDT5 is important for DNA repair
    Name: Wright, R. Role: Autor Publishing date: 2022
    Vol.: 41 No.: 12
  • Frontiers in Endocrinology, Global signalling network analysis of luminal T47D breast cancer cells in response to progesterone
    Name: Wright, R. Role: Autor Publishing date: 2022
    Start page: 1 End page: 19 Vol.: 13 No.: 19
  • Iscience, MyoD induces ARTD1 and nucleoplasmic poly-ADP-ribosylation during fibroblast to myoblast trans-differentiation
    Name: Bisceglie, L.; Hopp, A.-K.; Gunasekera, K.; Wright, R.; Le Dily, F.; Vidal, E.; Dall’Agnese, A.; Caputo, L.; Nicoletti, C.; Puri, P.L.; Beato, M.; Hottiger, M. Role: Autor Publishing date: 2021
    Vol.: 24 No.: 5
  • INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, Role of the nudt enzymes in breast cancer
    Name: Wright, R.; Beato, M. Role: Autor Publishing date: 2021
    Start page: 1 End page: 14 Vol.: 22 No.: 5
    DOI: https://dx.doi.org/10.3390/ijms22052267 ISSN or title: 1661-6596
  • Journal of molecular endocrinology, 90 YEARS OF PROGESTERONE: Molecular mechanisms of progesterone receptor action on the breast cancer genome
    Name: Beato, M.; Wright, R.; Le Dily, F. Role: Autor Publishing date: 2020
    Start page: T65 End page: T79 Vol.: 65 No.: 1
    DOI: https://dx.doi.org/10.1530/JME-19-0266 ISSN or title: 0952-5041
  • CANCERS, Expression of oncogenic drivers in 3D cell culture depends on nuclear ATP synthesis by NUDT5
    Name: Pickup, K.E.; Pardow, F.; Carbonell, J.; Lioutas, A.; Villanueva, J.; Wright, R.; Beato, M. Role: Autor Publishing date: 2019
    Vol.: 11 No.: 9
    DOI: https://dx.doi.org/10.3390/cancers11091337 ISSN or title: 2072-6694
  • Trends in biochemical sciences, ATP, Mg2+, Nuclear Phase Separation, and Genome Accessibility
    Name: Wright, R.; Le Dily, F.; Beato, M. Role: Autor Publishing date: 2019
    Start page: 565 End page: 574 Vol.: 44 No.: 7
  • Molecular cell, Arginine Citrullination at the C-Terminal Domain Controls RNA Polymerase II Transcription
    Name: Sharma, P.; Lioutas, A.; Fernández-Fuentes, N.; Quílez, J.; Carbonell, J.; Wright, R.; Di Vona, C.; Le Dily, F.; Schueller, R.; Eick, D.; Oliva, B.; Beato, M. Role: Autor Publishing date: 2019
    Vol.: 73 No.: 1
  • Genome research, Hormone-control regions mediate steroid receptor–dependent genome organization
    Name: Le Dily, F.; Vidal, E.; Cuartero, Y.; Quílez, J.; Nacht, A.; Vicent, G.; Carbonell, J.; Sharma, P.; Villanueva, J.; Ferrari, R.; de Llobet, L.; Verde, G.; Wright, R.; Beato, M. Role: Autor Publishing date: 2019
    Start page: 29 End page: 39 Vol.: 29 No.: 1
    DOI: https://dx.doi.org/10.1101/gr.243824.118 ISSN or title: 1088-9051
  • CANCERS, Unliganded Progesterone Receptor Governs Estrogen Receptor Gene Expression by Regulating DNA Methylation in Breast Cancer Cells
    Name: Verde, G.; de Llobet, L.; Wright, R.; Quílez, J.; Peiró, S.; Le Dily, F.; Beato, M. Role: Autor Publishing date: 2018
    Vol.: 10 No.: 10
    DOI: https://dx.doi.org/10.3390/cancers10100371 ISSN or title: 2072-6694
  • Nature communications, Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells
    Name: Page, B.D.G.; Valerie, N.C.K.; Wright, R.; Wallner, O.; Isaksson, R.; Carter, M.; Rudd, S.G.; Jemth, A.S.; Almlof, I.; Font-Mateu, J.; Llona-Minguez, S.; Baranczewski, P.; Jeppsson, F.; Homan, E.; Almqvist, H.; Axelsson, H.; Regmi, S.; Gustavsson, A.; Lundback, T.; Scobie, M.; Stromberg, K.; Stenmark, P.; Beato, M.; Helleday, T. Role: Autor Publishing date: 2018
    Vol.: 9
  • Nucleus-Austin, Insight into the machinery that oils chromatin dynamics
    Name: Wright, R.; Fernández-Fuentes, N.; Oliva, B.; Beato, M. Role: Autor Publishing date: 2016
    Start page: 532 End page: 539 Vol.: 7 No.: 6
  • Embo journal, Hormone-induced repression of genes requires BRG1-mediated H1.2 deposition at target promoters
    Name: Nacht, A. S.; Pohl, A.; Zaurin, R.; Soronellas, D.; Quílez, J.; Sharma, P.; Wright, R.; Beato, M.; Vicent, G. Role: Autor Publishing date: 2016
    Start page: 1822 End page: 1843 Vol.: 35 No.: 16
    ISSN or title: 0261-4189
  • Science, ADP-ribose-derived nuclear ATP synthesis by NUDIX5 is required for chromatin remodeling
    Name: Wright, R.; Lioutas, A.; Le Dily, F.; Soronellas, D.; Pohl, A.; Bonet, J.; Nacht, A. S.; Samino, S.; Font-Mateu, J.; Vicent, Guillermo P.; Wierer, M.; Trabado, M.A.; Schelhorn, C.; Carolis, C.; Macias, M.J.; Yanes, O.; Oliva, B.; Beato, M. Role: Autor Publishing date: 2016
    Start page: 1221 End page: 1225 Vol.: 352 No.: 6290
    DOI: https://dx.doi.org/10.1126/science.aad9335 ISSN or title: 0036-8075
  • Biochimica et Biophysica Acta-Gene Regulatory Mechanisms, Linker histones in hormonal gene regulation
    Name: Vicent, G.; Wright, R.; Beato, M. Role: Autor Publishing date: 2016
    Start page: 520 End page: 525 Vol.: 1859 No.: 3
  • Cell research, DNA damage and gene transcription: accident or necessity?
    Name: Beato, M.; Wright, R.; Vicent, Guillermo P. Role: Autor Publishing date: 2015
    Start page: 769 End page: 770 Vol.: 25 No.: 7
    DOI: https://dx.doi.org/10.1038/cr.2015.71 ISSN or title: 1001-0602
  • Genes and development, Distinct structural transitions of chromatin topological domains correlate with coordinated hormone-induced gene regulation
    Name: Le Dily, F.; Bau, D.; Pohl, A.; Vicent, G.; Serra, F.; Soronellas, D.; Castellano, G.; Wright, R.; Ballare, C.; Filion, G.; Marti-Renom, M.; Beato, M. Role: Autor Publishing date: 2014
    Start page: 2151 End page: 2162 Vol.: 28 No.: 19
    DOI: https://dx.doi.org/10.1101/gad.241422.114 ISSN or title: 0890-9369
  • Cell cycle, PARty promoters Hormone-dependent gene regulation requires CDK2 activation of PARP1
    Name: Wright, R.; Beato, M. Role: Autor Publishing date: 2012
    Start page: 4291 End page: 4293 Vol.: 11 No.: 23
    DOI: https://dx.doi.org/10.4161/cc.22531 ISSN or title: 1538-4101
  • Genes and development, CDK2-dependent activation of PARP-1 is required for hormonal gene regulation in breast cancer cells
    Name: Wright, R.; Castellano, G.; Bonet, J.; Le Dily, F.; Font Mateu, J.; Ballare, C.; Nacht, S.; Soronellas, D.; Oliva, B.; Beato, M. Role: Autor Publishing date: 2012
    Start page: 1972 End page: 1983 Vol.: 26 No.: 17
    DOI: https://dx.doi.org/10.1101/gad.193193.112 ISSN or title: 0890-9369
  • Progesterone Signaling to Chromatin in Breast Cancer Cells. Two Initial Cycles of Remodeling
    Publishing date: 2012 Doi: 10.1007/978-1-4614-1764-4_2 Isbn: 978-1-4614-1764-4
Course 2024-2025 - Period: 01/09/2024 - 31/08/2025
  • Bachelor’s Degree
    Bachelor's Degree in Dentistry
    • - Human Biology 1
    • - Human Biology 2
Course 2023-2024 - Period: 01/09/2023 - 31/08/2024
  • Bachelor’s Degree
    Bachelor's Degree in Dentistry
    • - Human Biology 1
    • - Human Biology 2
Course 2022-2023 - Period: 01/09/2022 - 31/08/2023
  • Bachelor’s Degree
    Bachelor's Degree in Biomedical Sciences
    • - Cancer Biology
    Bachelor's Degree in Dentistry
    • - Microbiology and Immunology
    • - Human Biology 2
    • - Human Biology 1
Course 2021-2022 - Period: 01/09/2021 - 31/08/2022
  • Bachelor’s Degree
    Bachelor's Degree in Dentistry
    • - Human Biology 2
    • - Microbiology and Immunology
Course 2020-2021 - Period: 01/09/2020 - 31/08/2021
  • Bachelor’s Degree
    Bachelor's Degree in Dentistry
    • - Microbiology and Immunology
Course 2019-2020 - Period: 01/09/2019 - 31/08/2020
  • Bachelor’s Degree
    Bachelor's Degree in Dentistry
    • - Microbiology and Immunology
Course 2018-2019 - Period: 01/09/2018 - 31/08/2019
  • Bachelor’s Degree
    Bachelor's Degree in Dentistry
    • - Microbiology and Immunology