The main objective is to establish novel systems and devices that may stimulate the regeneration of injured or damaged tissue. The Institute is subdivided into four main research areas:
Substrates for tissue regeneration. One key aspect of our research will be to develop novel biomaterials and substrates that are able to guide cells into specific lineages in order to stimulate the regeneration of damaged tissue. This will be performed by tuning the chemical and physical features of the biomaterials to mimic the native structure of tissues and organs.
Biomolecule/Cell delivery systems.Our aim is to mimic the regenerative pathways of native tissues by releasing multiple molecules involved in tissue regeneration. We will achieve this through the sequential delivery of therapeutic molecules and/or ions, as well as by encapsulating cells that are able to release signalling molecules to the surrounding tissues. We aim to obtain fibre-based systems that can be easily applied to 3D printing to allow allocating cells and molecules in specific allocations.
Theranostics systems. The objective is to design and fabricate systems that will be used as therapeutic as well as diagnostic systems. In this sense, we will perform research on nano-cluster based nanoparticles for the intracellular delivery of therapeutic agents as well as on the design of bio-sensors for the detection of specific bacteria.
Dental materials. This research lines aims to improve materials currently being used in the field of Dentistry, such as endodontic materials and dental implants, to improve their activity and enhance the success of the implanted materials.