Directory

TERRIENTE FÉLIX, Javier

Department of Basic Areas

TERRIENTE FÉLIX, Javier

CV

Teacher profile

Basic Areas, DEPARTMENT OF BASIC SCIENCIES. Universitat Internacional de Catalunya

Education

Doctor Biología Molecular, Universidad Autónoma de Madrid
Master Biología molecular, Universidad Autónoma de Madrid
Llicenciat Bioquímica, Universidad de Granada

Professional experience

• 06/2013 – Now: Co-founder and Chief Scientific Officer (CSO) at ZeClinicsand ZeCardio Therapeutics.
• 09/2011 – 12/2016: Assistant Professor / Postdoctoral researcher (Beatriu dePinos Fellow) at DECXS/UPF (Barcelona/Spain).
• 04/2007 – 08/2011: Postdoctoral researcher (Marie Curie IE Fellow) atNIMR/MRC (London/UK).

Publicacions
• Neuronal subtype specification within a lineage by opposing temporal feed-forward loopsM Baumgardt, D Karlsson, J Terriente, FJ Díaz-Benjumea, S Thor
• Cell segregation in the vertebrate hindbrain relies on actomyosin cables located at the interhombomeric boundaries S Calzolari, J Terriente, C Pujades The EMBO journal
• ZeGlobalTox: an innovative approach to address organ drug toxicity using zebrafish C Cornet, S Calzolari, R Miñana-Prieto, S Dyballa, E Van Doornmalen, ...International Journal of Molecular Sciences 18 (4), 864
• Combining zebrafish and CRISPR/Cas9: toward a more efficient drug discovery pipeline
C Cornet, V Di Donato, J Terriente Frontiers in pharmacology 9, 703
• The role of the T-box gene optomotor-blind in patterning the Drosophila wing D del Álamo Rodrı́guez, JT Felix, FJ Dı́az-Benjumea
Developmental biology 268 (2), 481-492
• Different mechanisms initiate and maintain wingless expression in the Drosophila wing hingeDA Rodríguez, J Terriente, MI Galindo, JP Couso, FJ Díaz-BenjumeaOxford University Press for The Company of Biologists Limited 129 (17), 3995 …
• Signalling from hindbrain boundaries regulates neuronal clustering that patterns neurogenesis J Terriente, SS Gerety, T Watanabe-Asaka, R Gonzalez-Quevedo, ... Development 139 (16), 2978-2987
• The Drosophila gene zfh2 is required to establish proximal-distal domains in the wing disc J Terriente, D Perea, M Suzanne, FJ Díaz-Benjumea Developmental biology 320 (1), 102-112
• Nab controls the activity of the zinc-finger transcription factors Squeeze and Rotund in Drosophila development JT Félix, M Magariños, FJ Díaz-Benjumea Oxford University Press for The Company of Biologists Limited 134 (10), 1845 …
• Use of zebrafish embryos for small molecule screening related to cancer J Terriente, C Pujades Developmental Dynamics 242 (2), 97-107
• Loss of the sphingolipid desaturase DEGS1 causes hypomyelinating leukodystrophy
DC Pant, I Dorboz, A Schluter, S Fourcade, N Launay, J Joya, ... The Journal of clinical investigation 129 (3), 1240-1256
• Distinct regulatory mechanisms act to establish and maintain Pax3 expression in the developing neural tube S Moore, V Ribes, J Terriente, D Wilkinson, F Relaix, J Briscoe PLoS genetics 9 (10), e1003811
• Retinoid acid specifies neuronal identity through graded expression of Ascl1 J Jacob, J Kong, S Moore, C Milton, N Sasai, R Gonzalez-Quevedo, ... Current Biology 23 (5), 412-418
• Yap/Taz-TEAD activity links mechanical cues to progenitor cell behavior during zebrafish hindbrain segmentation A Voltes, CF Hevia, C Engel-Pizcueta, C Dingare, S Calzolari, J Terriente, ... Development 146 (14), dev176735
• Spitz/EGFr signalling via the Ras/MAPK pathway mediates the induction of bract cells in Drosophila legs D del Álamo, J Terriente, FJ Díaz-Benjumea Oxford University Press for The Company of Biologists Limited 129 (8), 1975-1982
• Evolutionary emergence of the rac3b/rfng/sgca regulatory cluster refined mechanisms for hindbrain boundaries formation
J Letelier, J Terriente, I Belzunce, A Voltes, CA Undurraga, R Polvillo, ... Proceedings of the National Academy of Sciences 115 (16), E3731-E3740
• Multiplex analysis platform for endocrine disruption prediction using zebrafish S Jarque, J Ibarra, M Rubio-Brotons, J García-Fernández, J Terriente International journal of molecular sciences 20 (7), 1739
• Switching to zebrafish neurobehavioral models: The obsessive–compulsive disorder paradigm D D’Amico, X Estivill, J Terriente
European Journal of Pharmacology 759, 142-150
• Comparison of zebrafish larvae and hiPSC cardiomyocytes for predicting drug-induced cardiotoxicity in humans
S Dyballa, R Minana, M Rubio-Brotons, C Cornet, T Pederzani, ... Toxicological Sciences 171 (2), 283-295
• Cell segregation in the vertebrate hindbrain: a matter of boundaries
J Terriente, C Pujades Cellular and molecular life sciences 72 (19), 3721-3730
• ZeOncoTest: refining and automating the zebrafish xenograft model for drug discovery in cancer C Cornet, S Dyballa, J Terriente, V Di Giacomo Pharmaceuticals 13 (1), 1
• Temporal and spatial windows delimit activation of the outer ring of wingless in the Drosophila wing D Perea, J Terriente, FJ Díaz Benjumea Developmental biology 328 (2), 445-455
• Morphometric analysis of developing zebrafish embryos allows predicting teratogenicity modes of action in higher vertebrates S Jarque, M Rubio-Brotons, J Ibarra, V Ordoñez, S Dyballa, R Miñana, ... Reproductive Toxicology 96, 337-348
• Crispr meets zebrafish: Accelerating the discovery of new therapeutic targets
D Rubbini, C Cornet, J Terriente, V Di Donato SLAS DISCOVERY: Advancing the Science of Drug Discovery 25 (6), 552-567
• The CRISPR/Cas system in zebrafish F De Santis, J Terriente, V Di Donato Behavioral and Neural Genetics of Zebrafish, 293-307
• Yap/Taz-TEAD activity links mechanical cues to cell progenitor behavior during hindbrain segmentation A Voltes, CF Hevia, C Dingare, S Calzolari, J Terriente, C Norden, ... bioRxiv, 366351
• An Inter-Laboratory Case Study to harmonize Zebrafish Light-Dark Transition Test to predict Developmental Neurotoxicity for the OECD Guidance Document A Alzualde, JH Hsieh, L Ellis, V Schiavone, L Truong, J Legradi, ... INTERNATIONAL JOURNAL OF TOXICOLOGY 41 (1), 55-56
• Zebrafish, an innovative alternative model in preclinical studies R Minana-Prieto, S Jarque, M Rubio-Brotons, J Ibarra, V Ordonez, ...
Toxicology Letters 350, S142-S143
• High-throughput teratogenicity screening validation in zebrafish embryos R Minana-Prieto, S Jarque, J Ibarra, M Rubio-Brotons, J Terriente TOXICOLOGY LETTERS 314, S294-S294
• Biallelic mutations of the dihydroceramide desaturase DEGS1 gene cause a novel hypomyelinating leukodystrophy with a therapeutic hope A Pujol, D Pant, A Schluter, N Launay, S Aguilera, M Willis, L Colleaux, ... EUROPEAN JOURNAL OF HUMAN GENETICS 27, 753-753
• ZECARDIO: A zebrafish genetic screening platform for cardiovascular disease association studies V Di Donato, S Dyballa, J Terriente
EUROPEAN JOURNAL OF HUMAN GENETICS 27, 166-166
• Yap/Taz-Tead Activity Links Mechanical Cues to Specific Cell Fate Within the Hindbrain Boundaries A Voltes, CF Hevia, C Dingare, S Calzolari, J Terriente, C Norden, ... bioRxiv, 366351
• A new way for global toxicity assessment C Cornet, R Minana, S Calzolari, D D’amico, J Terriente Toxicology Letters, S288
• Repression of the proneural factor Ascl1 by retinoid signalling restricts neuronal fate choices in the ventral spinal cord J Jacob, S Moore, C Milton, R Gonzalez-Quevedo, J Terriente, J Briscoe International Journal of Developmental Neuroscience 8 (28), 662-663
• Miscellaneous II J Terriente, DG Wilkinson MECHANISMS OF DEVELOPMENT 126, S329-S335
• 22-P001 FLEET: A new tool for gain of function and cell lineage analysis in zebrafish J Terriente, DG Wilkinson Mechanisms of Development, S329
• From stem cell to unique neuron: Temporal transitions in an identified CNS progenitor cell by feedforward combinatorial coding M Baumgardt, D Karlsson, J Terriente, F J Diaz-Benjumea, S Thor
• A newly identified transcriptional co-factor of the ZN-finger gene SQZ mediate all its functions in the ventral nerve cord development
J Terriente, M Magarinos, FJ Diaz-Benjumea JOURNAL OF NEUROGENETICS 20 (3-4), 237-237
• Submission PDF J Letelier, J Terriente, I Belzunce, A Voltes, C Undurraga, R Polvillo, ... PNAS 67, 68
• Supplemental Information Retinoid Acid Specifies Neuronal Identity through Graded Expression of Ascl1J Jacob, J Kong, S Moore, C Milton, N Sasai, R Gonzalez-Quevedo, ..