Directory
ALDEA MALO, Martí
CV
Teacher profile
Professor Catedràtic
Basic Areas, DEPARTMENT OF BASIC SCIENCIES. Universitat Internacional de Catalunya
Academic curriculum
- Otros Universitat Autònoma de Barcelona
Education
Doctor in Biological Science, UNIVERSITAT AUTÒNOMA DE BARCELONA
Bachelor's Degree in Biochemistry, UNIVERSITAT AUTÒNOMA DE BARCELONA
Bachelor's Degree in Biological Sciences, UNIVERSITAT AUTÒNOMA DE BARCELONA
Bachelor's Degree in Biochemistry, UNIVERSITAT AUTÒNOMA DE BARCELONA
Bachelor's Degree in Biological Sciences, UNIVERSITAT AUTÒNOMA DE BARCELONA
Professional experience
2010 Research Professor, Higher Council for Scientific Research
2003-2009 University Professor, Universitat de Lleida
1992-2002 Full University Professor, Universitat de Lleida
1988-1991 Postdoctoral Reincorporation Fellow, C. Biological Research. CSIC
1987-1988 Research Associate, Dept. of Genetics. UGA. USES.
1985-1986 Postdoctoral Fellow, Dept. of Genetics. UGA. USES.
1983-1985 Postdoctoral Fellow, Cell Biology Institute. CSIC
1978-1981 Doctoral Scholar, Dept. Microbiology. UAB.
1977-1983 Assistant Professor, C. General Biology. UAB.
2003-2009 University Professor, Universitat de Lleida
1992-2002 Full University Professor, Universitat de Lleida
1988-1991 Postdoctoral Reincorporation Fellow, C. Biological Research. CSIC
1987-1988 Research Associate, Dept. of Genetics. UGA. USES.
1985-1986 Postdoctoral Fellow, Dept. of Genetics. UGA. USES.
1983-1985 Postdoctoral Fellow, Cell Biology Institute. CSIC
1978-1981 Doctoral Scholar, Dept. Microbiology. UAB.
1977-1983 Assistant Professor, C. General Biology. UAB.
Publications
Articles
- Pérez-Paredes, A.; Artés, M.H.; Moreno, D.; Clotet, J.; Aldea, M., (2022), "Mad3 modulates the G1 Cdk and acts as a timer in the Start network", Science advances, vol. 8, No. 18, ISSN: 2375-2548.
- Yahya, G.; Pérez-Paredes, A.; Mendoza, M.; Parisi, E.; Moreno, D.; Artés, M.H.; Gallego, C.; Aldea, M., (2021), "Stress granules display bistable dynamics modulated by Cdk", Journal of cell biology, vol. 220, No. 3, ISSN: 0021-9525.
- Moreno, D.; Jenkis, K.; Morlot, S.; Charvin, G.; Csikasz-Nagy, A.; Aldea, M., (2019), "Proteostasis collapse, a hallmark of aging, hinders the chaperone-Start network and arrests cells in G1", eLife, vol. 8, ISSN: 2050-084X.
- Moreno, D.; Aldea, M., (2019), "Coincidence analysis of molecular dynamics by raster image correlation spectroscopy", Methods in Molecular Biology, vol. 2040, pp. 375-384, ISSN: 1940-6029 10643745.
- Moreno, D.; Parisi, E.; Yahya, G.; Vaggi, F.; Csikász, A.; Aldea, M., (2019), "Competition in the chaperone-client network subordinates cell-cycle entry to growth and stress", Life Science Alliance, vol. 2, No. 2, ISSN: 2575-1077.
- Parisi, E.; Yahya, G.; Flores, A.; Aldea, M., (2018), "Cdc48/p97 segregase is modulated by cyclin-dependent kinase to determine cyclin fate during G1 progression", Embo journal, vol. 37, No. 16, ISSN: 0261-4189.
- Martínez-Láinez, JM.; Moreno, D.; Parisi, E.; Clotet, J.; Aldea, M., (2018), "Centromeric signaling proteins boost G1 cyclin degradation and modulate cell size in budding yeast", PLOS biology, vol. 16, No. 8, ISSN: 1544-9173.
- Aldea, M.; Jenkins, K.; Csikász, A., (2017), "Growth Rate as a Direct Regulator of the Start Network to Set Cell Size", Frontiers in cell and developmental biology, vol. 5, pp. 57-62, ISSN: 2296-634X.
- Aldea, M., (2017), "Compartmentalization of ER-bound chaperone confines protein deposit formation to the aging yeast cell", Current biology, vol. 27, pp. 773-783, ISSN: 0960-9822.
- Deniz, Ö.; Flores, Ó.; Aldea, M.; Soler-López, M.; Orozco, M., (2016), "Nucleosome architecture throughout the cell cycle", Scientific Reports, vol. 6, No. 19729, pp. 1-11, ISSN: 2045-2322.
- Georgieva, M.V.; Yahya, G.; Codó, L.; Ortíz, R.; Gallego, C.; Orozco, M.; Aldea, M., (2015), "Inntags: small self-structured epitopes for innocuous protein tagging", Nature methods, vol. 12, No. 10, pp. 955-958, ISSN: 1548-7091.
- Yahya, G.; Parisi, E.; Flores, A.; Gallego, C.; Aldea, M., (2014), "A Whi7-anchored loop controls de G1 Cdk-cyclin complex at Start.", Molecular cell, vol. 53, pp. 115-126, ISSN: 1097-2765.
- Menoyo, S.; Ricco, N.; Bru, S.; Hernández-Ortega, S; Escoté, X.; Aldea, M.; Clotet, J., (2013), "Phosphate-Activated Cyclin-Dependent Kinase Stabilizes G(1) Cyclin To Trigger Cell Cycle Entry", Mol Cell Biol., vol. 33(7), pp. 1273-1284, ISSN: 1098-5549.
- Ferrezuelo, F.; Colomina, N.; Palmisano, A.; Garí, E.; Gallego, C.; Csikasz-Nagy, A.; Aldea, M., (2012), "The critical size is set at a single-cell level by growth rate to attain homeostasis and adaptation", Nature communications, vol. 3, No. 1012, pp. 1-11, ISSN: 2041-1723.
- Ferrezuelo, F.; Colomina, N.; Futcher, B.; Aldea, M., (2010), "The transcriptional network activated by Cln3 cyclin at the G1-to-S transition of the yeast cell cycle", Genome biology, vol. 11, No. 6, pp. 1-9, ISSN: 1474-760X.
- Vergés, E.; Colomina, N.; Garí, E.; Gallego, C.; Aldea, M., (2007), "Cyclin Cln3 is retained at the ER and released by the J chaperone Ydj1 in late G1 to trigger cell cycle entry", Molecular cell, vol. 26, No. 5, pp. 649-662, ISSN: 1097-2765.
- Clotet, J.; Escoté, X.; Adrover, MÀ; Yaakov, G.; Garí, E.; Aldea, M.; De Nadal, E.; Posas, F., (2006), "Phosphorylation of Hsl1 by Hog1 leads to a G2 arrest essential for cell survival at high osmolarity.", Embo journal, vol. 25, pp. 2338-2346, ISSN: 0261-4189.
- Clotet, J.; Garí, E.; Aldea, M.; Ariño, J., (1999), "The yeast Ser/Thr phosphatases SIT4 and PPZ1 play opposite roles in the regulation of the cell cycle.", Molecular and cellular biology, vol. 19, pp. 2408-2415, ISSN: 0270-7306.
Projects and research
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Ultradynamic protein assemblies and network channeling01/01/2024 - 31/12/2026IP: Aldea, M.
Agencia EStatal de Investigación
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Protein cluster dynamics and network channeling01/06/2020 - 31/05/2023IP: Aldea, M.
Agencia EStatal de Investigación
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Proteotoxic aggregates, chaperome alterations and cell proliferation decline during cell aging30/12/2016 - 29/12/2019IP: Aldea, M.
MINE - MINECO. Ministerio de Economía y Competitividad
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Prions and aggregons as inhibitors of Start: a path to cell ageing.01/01/2014 - 31/12/2016IP: Aldea, M.
MINE - MINECO. Ministerio de Economía y Competitividad
Activities
- Federation of European Biochemical Societies Congress Ponència convidada "Growth sensors in the Start network to set cell size", 2017.