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HERNÁNDEZ ORTEGA, Sara

HERNÁNDEZ ORTEGA, Sara

Professor Col·laboradora
Faculty of Medicine and Health Sciences
Department of Biomedical Sciences

Contact

Tel. +34 932 541 800
Ext. 5262
shernandez@uic.es
ORCID
  • Academic training
  • Professional experience
  • Publications
    • Articles
  • Subjects taught
  • Máster en Biomedicina
  • Universitat de Barcelona
  • Licenciada en Biotecnología
  • Universitat de Vic
  • Biologia Molecular
  • Universitat Internacional de Catalunya
Universitat Internacional de Catalunya
Professor gen. 2010 - present
Postdoctoral researcher 2014 - 2016
During my Postdoctorate I developed several projects in cancer research that are about to be published. In addition, I taught different PhD students with whom I developed my leadership skills, communication skills and passion for imparting knowledge.
Doctoral student - Oct. 2009 - 2014
I worked in J. Clotet's group doing my PhD in molecular biology researching the cell cycle with S. cerevisiae and also cell cultures. Here I have learned new techniques and developed new skills such as being more self-sufficient and coordinating my own research.
Sant Joan de Déu Foundation graphic. Manager of Innovation Projects
Sant Joan de Déu Foundation 2018 - 2020
Building projects to transform ideas into concepts and impact medical care.
Share4Rare chart. Compartir4Raro project manager Jul. 2018 - ago 2020
PlasmoFAB Chart – PlasmoFAB Tutor Oct. 2017 - December. 2019, Greece
PLASMOFab aims to develop plasmonics compatible with CMOS in a generic planar integration process as a means to consolidate photonic and electronic integration. PLASMOFab will use wafer-scale integration to demonstrate the low cost, volume manufacturing and high performance of powerful PICs. The new integration technology will reveal a series of innovations with profound benefits from the enhanced interaction between light and matter enabled by plasmonics in optical transmitters and biosensors
  • Experimental and molecular medicine, Phosphoregulation of the oncogenic protein regulator of cytokinesis 1 (PRC1) by the atypical CDK16/CCNY complex
    Name: Hernández Ortega, Sara; Sánchez-Botet, A.; Quandt Herrera, Eva; Masip Sales, Núria; Gasa, L.; Verde, G.; Jiménez Jiménez, Javier; Levin, R.; Rugatanira, F.; Burlingame, A.; Ribeiro, MP; Shokat, K.; Clotet Erra, Josep Role: Autor Publishing date: 2019
    Start page: 1 End page: 17 Vol.: 51 No.: 4
    DOI: 10.1038/s12276-019-0242-2 ISSN or title: 1226-3613
  • Scientific Reports, The atypical cyclin CNTD2 promotes colon cancer cell proliferation and migration
    Name: Sánchez-Botet, A.; Gasa, L.; Quandt Herrera, Eva; Hernández Ortega, Sara; Jiménez Jiménez, Javier; Mezquita Mas, Pau; Carrasco, M.; Kron, S.; Vidal, A.; Villanueva, A.; Ribeiro, MP; Clotet Erra, Josep Role: Autor Publishing date: 2018
    Vol.: 8 No.: 1
    DOI: 10.1038/s41598-018-30307-x ISSN or title: 2045-2322
  • DNA repair, Polyphosphate is a key factor for cell survival after DNA damage in eukaryotic cells
    Name: Bru, Samuel; Samper-Martín, Bàrbara; Quandt, Eva; Hernández-Ortega, Sara; Martínez-Laínez, Joan M.; Garí, Eloi; Rafel, Marta; Torres-Torronteras, Javier; Martí, Ramón; Ribeiro, Mariana P.C.; Jiménez, Javier; Clotet, Josep Role: Autor Publishing date: 2017
    Start page: 171 End page: 178 Vol.: 57
    DOI: 10.1016/j.dnarep.2017.08.001 ISSN or title: 1568-7864
  • Scientific Reports, A systematic analysis of orphan cyclins reveals CNTD2 as a new oncogenic driver in lung cancer
    Name: Gasa, L.; Sánchez-Botet, A.; Quandt Herrera, Eva; Hernández Ortega, Sara; Jiménez Jiménez, Javier; Carrasco, M.; Simonetti, S.; Kron, S.; Ribeiro, MP; Nadal, E.; Villanueva, A.; Clotet Erra, Josep Role: Autor Publishing date: 2017
    Vol.: 7 No.: 1
    DOI: 10.1038/s41598-017-10770-8 ISSN or title: 2045-2322
  • Molecular Microbiology, Polyphosphate is involved in cell cycle progression and genomic stability in Saccharomyces cerevisiae
    Name: Bru, Samuel; Martínez-Laínez, Joan Marc; Hernández-Ortega, Sara; Quandt, Eva; Torres-Torronteras, Javier; Martí, Ramón; Canadell, David; Ariño, Joaquin; Sharma, Sushma; Jiménez, Javier; Clotet, Josep Role: Autor Publishing date: 2016
    Start page: 367 End page: 380 Vol.: 101 No.: 3
    DOI: 10.1111/mmi.13396 ISSN or title: 0950-382X
  • Journal of biological chemistry, Defective in mitotic arrest 1 (Dma1) ubiquitin ligase controls G <sub>1</sub> cyclin degradation
    Name: Hernández-Ortega, Sara; Bru, Samuel; Ricco, Natalia; Ramírez, Sara; Casals, Núria; Jiménez, Javier; Isasa, Marta; Crosas, Bernat; Clotet, Josep Role: Autor Publishing date: 2013
    Start page: 4704 End page: 4714 Vol.: 288 No.: 7
    DOI: 10.1074/jbc.M112.426593 ISSN or title: 0021-9258
  • Molecular and cellular biology, Phosphate-activated cyclin-dependent kinase stabilizes G<sub>1</sub> cyclin to trigger cell cycle entry
    Name: Menoyo, S.; Ricco, N.; Bru, S.; Hernández-Ortega, S.; Escoté, X.; Aldea, M.; Cloteta, J. Role: Autor Publishing date: 2013
    Start page: 1273 End page: 1284 Vol.: 33 No.: 7
    DOI: 10.1128/MCB.01556-12 ISSN or title: 0270-7306
  • Cancer research, RANK induces epithelial-mesenchymal transition and stemness in human mammary epithelial cells and promotes tumorigenesis and metastasis
    Name: Hernández Ortega, Sara Role: Autor Publishing date: 2012
    Start page: 2879 End page: 2888 Vol.: 72 No.: 11
    DOI: 10.1158/0008-5472.CAN-12-0044 ISSN or title: 0008-5472
Course 2025-2026 - Period: 01/09/2025 - 31/08/2026
  • Bachelor's Degree
    Bachelor's Degree in Biomedical Sciences
    • - Final Degree Project
    • - Work Placement
    • - Entrepreneurship and Innovation
    • - External Laboratory Practices
  • Others
    Lifelong Learning Master's Degree in the Biomedical Business Management
    • - Trabajo Fin de Máster
    • - Prácticas Externas
    • - Acceso al Mercado, Finanzas y Marketing
    • - Introducción a la Industria Biomédica
    • - Propiedad Intelectual, Transferencia de Tecnología y Aspectos Regulatorios
    • - Capacidades Transversales: Gestión de Proyectos, Negociación y Comunicación
    • - Estrategia y Operaciones
Course 2024-2025 - Period: 01/09/2024 - 31/08/2025
  • Bachelor's Degree
    Bachelor's Degree in Biomedical Sciences
    • - Work Placement
    • - Structure and Function: Gastrointestinal and Reproductive Systems
    • - Final Degree Project
  • Others
    Lifelong Learning Master's Degree in Biomedical Business Management
    • - Prácticas Externas
    • - Trabajo Fin de Máster
    • - Introducción a la Industria Biomédica
    • - Capacidades Transversales: Gestión de Proyectos, Negociación y Comunicación
    • - Propiedad Intelectual, Transferencia de Tecnología y Aspectos Regulatorios
Course 2023-2024 - Period: 01/09/2023 - 31/08/2024
  • Bachelor's Degree
    Bachelor's Degree in Biomedical Sciences
    • - Cellular and Molecular Pathology
    • - Biochemistry II
    • - Final Degree Project
  • Official Master
    University Master's Degree in Experimental Biomedical Research
    • - Scientific Background and Integrity in Research
Course 2022-2023 - Period: 01/09/2022 - 31/08/2023
  • Bachelor's Degree
    Bachelor's Degree in Biomedical Sciences
    • - Cellular and Molecular Pathology
    • - Integrated Biomedicine I
    • - Final Degree Project
    Bachelor's Degree in Medicine
    • - Body Structure and Function: Gastrointestinal System and Metabolism
Course 2021-2022 - Period: 01/09/2021 - 31/08/2022
  • Bachelor's Degree
    Bachelor's Degree in Biomedical Sciences
    • - Cellular and Molecular Pathology
    • - Biochemistry I
    • - Introduction to Biomedicine
    • - Biochemistry II
    • - Final Degree Project
    • - Work Placement
    Bachelor's Degree in Medicine
    • - Body Structure and Function: Gastrointestinal System and Metabolism
Course 2020-2021 - Period: 01/09/2020 - 31/08/2021
  • Bachelor's Degree
    Bachelor's Degree in Biomedical Sciences
    • - Biochemistry I
    • - Biochemistry II
    • - Introduction to Biomedicine
    • - Integrated Biomedicine I
    • - Cellular and Molecular Pathology
    Bachelor's Degree in Medicine
    • - Biochemistry
    • - Body Structure and Function: Gastrointestinal System and Metabolism
Course 2019-2020 - Period: 01/09/2019 - 31/08/2020
  • Bachelor's Degree
    Bachelor's Degree in Biomedical Sciences
    • - Biochemistry I
    • - Biochemistry II
    Bachelor's Degree in Medicine
    • - Body Structure and Function: Gastrointestinal System and Metabolism
Course 2017-2018 - Period: 01/09/2017 - 31/08/2018
  • Bachelor's Degree
    Bachelor's Degree in Medicine
    • - Cell Biology
Course 2016-2017 - Period: 01/09/2016 - 31/08/2017
  • Bachelor's Degree
    Bachelor's Degree in Medicine
    • - Biochemistry
Course 2015-2016 - Period: 01/09/2015 - 31/08/2016
  • Bachelor's Degree
    Bachelor's Degree in Medicine
    • - Biochemistry
    • - Body Structure and Function: Gastrointestinal System and Metabolism
    • - Molecular Biology
    Bachelor's Degree in Nursing
    • - Biology of Caregiving
Course 2014-2015 - Period: 01/09/2014 - 31/08/2015
  • Bachelor's Degree
    Bachelor's Degree in Medicine
    • - Body Structure and Function: Gastrointestinal System and Metabolism
    • - Biochemistry
    • - Cell Biology
    • - Molecular Biology
    Bachelor's Degree in Nursing
    • - Biology of Caregiving
Course 2013-2014 - Period: 01/09/2013 - 31/08/2014
  • Bachelor's Degree
    Bachelor's Degree in Medicine
    • - Body Structure and Function: Gastrointestinal System and Metabolism
    • - Biochemistry
    • - Molecular Biology
Course 2012-2013 - Period: 01/09/2012 - 31/08/2013
  • Bachelor's Degree
    Bachelor's Degree in Medicine
    • - Biochemistry
    • - Molecular Biology
    • - Body Structure and Function: Gastrointestinal System and Metabolism
    Bachelor's Degree in Nursing
    • - Biology of Caregiving
Course 2011-2012 - Period: 01/09/2011 - 31/08/2012
  • Bachelor's Degree
    Bachelor's Degree in Dentistry
    • - Human Biology 1
    Bachelor's Degree in Medicine
    • - Biochemistry
    • - Estructura y Función: Sistema Endocrinológico y Digestivo
Course 2010-2011 - Period: 01/09/2010 - 31/08/2011
  • Bachelor's Degree
    Bachelor's Degree in Dentistry
    • - Human Biology 1
    Bachelor's Degree in Medicine
    • - Biochemistry
    • - Body Structure and Function: Endocrine and Digestive System
Course 2009-2010 - Period: 01/09/2009 - 31/08/2010
  • Bachelor's Degree
    Bachelor's Degree in Medicine
    • - Estructura y Función: Sistema Endocrinológico y Digestivo
    • - Molecular Biology

Academic training

  • Máster en Biomedicina
  • Universitat de Barcelona
  • Licenciada en Biotecnología
  • Universitat de Vic
  • Biologia Molecular
  • Universitat Internacional de Catalunya

Professional experience

Universitat Internacional de Catalunya
Professor gen. 2010 - present
Postdoctoral researcher 2014 - 2016
During my Postdoctorate I developed several projects in cancer research that are about to be published. In addition, I taught different PhD students with whom I developed my leadership skills, communication skills and passion for imparting knowledge.
Doctoral student - Oct. 2009 - 2014
I worked in J. Clotet's group doing my PhD in molecular biology researching the cell cycle with S. cerevisiae and also cell cultures. Here I have learned new techniques and developed new skills such as being more self-sufficient and coordinating my own research.
Sant Joan de Déu Foundation graphic. Manager of Innovation Projects
Sant Joan de Déu Foundation 2018 - 2020
Building projects to transform ideas into concepts and impact medical care.
Share4Rare chart. Compartir4Raro project manager Jul. 2018 - ago 2020
PlasmoFAB Chart – PlasmoFAB Tutor Oct. 2017 - December. 2019, Greece
PLASMOFab aims to develop plasmonics compatible with CMOS in a generic planar integration process as a means to consolidate photonic and electronic integration. PLASMOFab will use wafer-scale integration to demonstrate the low cost, volume manufacturing and high performance of powerful PICs. The new integration technology will reveal a series of innovations with profound benefits from the enhanced interaction between light and matter enabled by plasmonics in optical transmitters and biosensors

Publications

Articles

  • Experimental and molecular medicine, Phosphoregulation of the oncogenic protein regulator of cytokinesis 1 (PRC1) by the atypical CDK16/CCNY complex
    Name: Hernández Ortega, Sara; Sánchez-Botet, A.; Quandt Herrera, Eva; Masip Sales, Núria; Gasa, L.; Verde, G.; Jiménez Jiménez, Javier; Levin, R.; Rugatanira, F.; Burlingame, A.; Ribeiro, MP; Shokat, K.; Clotet Erra, Josep Role: Autor Publishing date: 2019
    Start page: 1 End page: 17 Vol.: 51 No.: 4
    DOI: 10.1038/s12276-019-0242-2 ISSN or title: 1226-3613
  • Scientific Reports, The atypical cyclin CNTD2 promotes colon cancer cell proliferation and migration
    Name: Sánchez-Botet, A.; Gasa, L.; Quandt Herrera, Eva; Hernández Ortega, Sara; Jiménez Jiménez, Javier; Mezquita Mas, Pau; Carrasco, M.; Kron, S.; Vidal, A.; Villanueva, A.; Ribeiro, MP; Clotet Erra, Josep Role: Autor Publishing date: 2018
    Vol.: 8 No.: 1
    DOI: 10.1038/s41598-018-30307-x ISSN or title: 2045-2322
  • DNA repair, Polyphosphate is a key factor for cell survival after DNA damage in eukaryotic cells
    Name: Bru, Samuel; Samper-Martín, Bàrbara; Quandt, Eva; Hernández-Ortega, Sara; Martínez-Laínez, Joan M.; Garí, Eloi; Rafel, Marta; Torres-Torronteras, Javier; Martí, Ramón; Ribeiro, Mariana P.C.; Jiménez, Javier; Clotet, Josep Role: Autor Publishing date: 2017
    Start page: 171 End page: 178 Vol.: 57
    DOI: 10.1016/j.dnarep.2017.08.001 ISSN or title: 1568-7864
  • Scientific Reports, A systematic analysis of orphan cyclins reveals CNTD2 as a new oncogenic driver in lung cancer
    Name: Gasa, L.; Sánchez-Botet, A.; Quandt Herrera, Eva; Hernández Ortega, Sara; Jiménez Jiménez, Javier; Carrasco, M.; Simonetti, S.; Kron, S.; Ribeiro, MP; Nadal, E.; Villanueva, A.; Clotet Erra, Josep Role: Autor Publishing date: 2017
    Vol.: 7 No.: 1
    DOI: 10.1038/s41598-017-10770-8 ISSN or title: 2045-2322
  • Molecular Microbiology, Polyphosphate is involved in cell cycle progression and genomic stability in Saccharomyces cerevisiae
    Name: Bru, Samuel; Martínez-Laínez, Joan Marc; Hernández-Ortega, Sara; Quandt, Eva; Torres-Torronteras, Javier; Martí, Ramón; Canadell, David; Ariño, Joaquin; Sharma, Sushma; Jiménez, Javier; Clotet, Josep Role: Autor Publishing date: 2016
    Start page: 367 End page: 380 Vol.: 101 No.: 3
    DOI: 10.1111/mmi.13396 ISSN or title: 0950-382X
  • Journal of biological chemistry, Defective in mitotic arrest 1 (Dma1) ubiquitin ligase controls G <sub>1</sub> cyclin degradation
    Name: Hernández-Ortega, Sara; Bru, Samuel; Ricco, Natalia; Ramírez, Sara; Casals, Núria; Jiménez, Javier; Isasa, Marta; Crosas, Bernat; Clotet, Josep Role: Autor Publishing date: 2013
    Start page: 4704 End page: 4714 Vol.: 288 No.: 7
    DOI: 10.1074/jbc.M112.426593 ISSN or title: 0021-9258
  • Molecular and cellular biology, Phosphate-activated cyclin-dependent kinase stabilizes G<sub>1</sub> cyclin to trigger cell cycle entry
    Name: Menoyo, S.; Ricco, N.; Bru, S.; Hernández-Ortega, S.; Escoté, X.; Aldea, M.; Cloteta, J. Role: Autor Publishing date: 2013
    Start page: 1273 End page: 1284 Vol.: 33 No.: 7
    DOI: 10.1128/MCB.01556-12 ISSN or title: 0270-7306
  • Cancer research, RANK induces epithelial-mesenchymal transition and stemness in human mammary epithelial cells and promotes tumorigenesis and metastasis
    Name: Hernández Ortega, Sara Role: Autor Publishing date: 2012
    Start page: 2879 End page: 2888 Vol.: 72 No.: 11
    DOI: 10.1158/0008-5472.CAN-12-0044 ISSN or title: 0008-5472
Course 2025-2026 - Period: 01/09/2025 - 31/08/2026
  • Bachelor's Degree
    Bachelor's Degree in Biomedical Sciences
    • - Final Degree Project
    • - Work Placement
    • - Entrepreneurship and Innovation
    • - External Laboratory Practices
  • Others
    Lifelong Learning Master's Degree in the Biomedical Business Management
    • - Trabajo Fin de Máster
    • - Prácticas Externas
    • - Acceso al Mercado, Finanzas y Marketing
    • - Introducción a la Industria Biomédica
    • - Propiedad Intelectual, Transferencia de Tecnología y Aspectos Regulatorios
    • - Capacidades Transversales: Gestión de Proyectos, Negociación y Comunicación
    • - Estrategia y Operaciones
Course 2024-2025 - Period: 01/09/2024 - 31/08/2025
  • Bachelor's Degree
    Bachelor's Degree in Biomedical Sciences
    • - Work Placement
    • - Structure and Function: Gastrointestinal and Reproductive Systems
    • - Final Degree Project
  • Others
    Lifelong Learning Master's Degree in Biomedical Business Management
    • - Prácticas Externas
    • - Trabajo Fin de Máster
    • - Introducción a la Industria Biomédica
    • - Capacidades Transversales: Gestión de Proyectos, Negociación y Comunicación
    • - Propiedad Intelectual, Transferencia de Tecnología y Aspectos Regulatorios
Course 2023-2024 - Period: 01/09/2023 - 31/08/2024
  • Bachelor's Degree
    Bachelor's Degree in Biomedical Sciences
    • - Cellular and Molecular Pathology
    • - Biochemistry II
    • - Final Degree Project
  • Official Master
    University Master's Degree in Experimental Biomedical Research
    • - Scientific Background and Integrity in Research
Course 2022-2023 - Period: 01/09/2022 - 31/08/2023
  • Bachelor's Degree
    Bachelor's Degree in Biomedical Sciences
    • - Cellular and Molecular Pathology
    • - Integrated Biomedicine I
    • - Final Degree Project
    Bachelor's Degree in Medicine
    • - Body Structure and Function: Gastrointestinal System and Metabolism
Course 2021-2022 - Period: 01/09/2021 - 31/08/2022
  • Bachelor's Degree
    Bachelor's Degree in Biomedical Sciences
    • - Cellular and Molecular Pathology
    • - Biochemistry I
    • - Introduction to Biomedicine
    • - Biochemistry II
    • - Final Degree Project
    • - Work Placement
    Bachelor's Degree in Medicine
    • - Body Structure and Function: Gastrointestinal System and Metabolism
Course 2020-2021 - Period: 01/09/2020 - 31/08/2021
  • Bachelor's Degree
    Bachelor's Degree in Biomedical Sciences
    • - Biochemistry I
    • - Biochemistry II
    • - Introduction to Biomedicine
    • - Integrated Biomedicine I
    • - Cellular and Molecular Pathology
    Bachelor's Degree in Medicine
    • - Biochemistry
    • - Body Structure and Function: Gastrointestinal System and Metabolism
Course 2019-2020 - Period: 01/09/2019 - 31/08/2020
  • Bachelor's Degree
    Bachelor's Degree in Biomedical Sciences
    • - Biochemistry I
    • - Biochemistry II
    Bachelor's Degree in Medicine
    • - Body Structure and Function: Gastrointestinal System and Metabolism
Course 2017-2018 - Period: 01/09/2017 - 31/08/2018
  • Bachelor's Degree
    Bachelor's Degree in Medicine
    • - Cell Biology
Course 2016-2017 - Period: 01/09/2016 - 31/08/2017
  • Bachelor's Degree
    Bachelor's Degree in Medicine
    • - Biochemistry
Course 2015-2016 - Period: 01/09/2015 - 31/08/2016
  • Bachelor's Degree
    Bachelor's Degree in Medicine
    • - Biochemistry
    • - Body Structure and Function: Gastrointestinal System and Metabolism
    • - Molecular Biology
    Bachelor's Degree in Nursing
    • - Biology of Caregiving
Course 2014-2015 - Period: 01/09/2014 - 31/08/2015
  • Bachelor's Degree
    Bachelor's Degree in Medicine
    • - Body Structure and Function: Gastrointestinal System and Metabolism
    • - Biochemistry
    • - Cell Biology
    • - Molecular Biology
    Bachelor's Degree in Nursing
    • - Biology of Caregiving
Course 2013-2014 - Period: 01/09/2013 - 31/08/2014
  • Bachelor's Degree
    Bachelor's Degree in Medicine
    • - Body Structure and Function: Gastrointestinal System and Metabolism
    • - Biochemistry
    • - Molecular Biology
Course 2012-2013 - Period: 01/09/2012 - 31/08/2013
  • Bachelor's Degree
    Bachelor's Degree in Medicine
    • - Biochemistry
    • - Molecular Biology
    • - Body Structure and Function: Gastrointestinal System and Metabolism
    Bachelor's Degree in Nursing
    • - Biology of Caregiving
Course 2011-2012 - Period: 01/09/2011 - 31/08/2012
  • Bachelor's Degree
    Bachelor's Degree in Dentistry
    • - Human Biology 1
    Bachelor's Degree in Medicine
    • - Biochemistry
    • - Estructura y Función: Sistema Endocrinológico y Digestivo
Course 2010-2011 - Period: 01/09/2010 - 31/08/2011
  • Bachelor's Degree
    Bachelor's Degree in Dentistry
    • - Human Biology 1
    Bachelor's Degree in Medicine
    • - Biochemistry
    • - Body Structure and Function: Endocrine and Digestive System
Course 2009-2010 - Period: 01/09/2009 - 31/08/2010
  • Bachelor's Degree
    Bachelor's Degree in Medicine
    • - Estructura y Función: Sistema Endocrinológico y Digestivo
    • - Molecular Biology