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CHOROSTECKI, Uciel Pablo

CHOROSTECKI, Uciel Pablo

Professor Col·laborador
Faculty of Medicine and Health Sciences
Department of Biomedical Sciences
researchgroups.uic.es/computational-rna-biology/

Contact

upchorostecki@uic.es
ORCID
linkedin
  • Academic training
  • Professional experience
  • Publications
    • Articles
  • Subjects taught
PhD in Biological Sciences, NATIONAL UNIVERSITY OF ROSARIO
Degree in Computer Science, NATIONAL UNIVERSITY OF ROSARIO
Group Leader of the Computational RNA Biology Lab. Co-Founder & CSO Kresko RNAtech
2019 - 2022 JdC-Incorporacion fellow. Barcelona Supercomputing Centre (BSC)
2017 - 2019 MSCA-IF Fellow. Centre for Genomic Regulation (CRG)
2016 - 2017 Bunge Y Born Postdoctoral Fellow. IBR Rosario, Argentina
  • Nucleic acids research, SIREs 3.0, an improved RNA prediction tool for iron-responsive elements
    Name: Suarez, C.; Navarro, M.; Chorostecki, U.; Sánchez, M. Role: Autor Publishing date: 2025
    DOI: 10.1093/nar/gkaf390 ISSN or title: 0305-1048
  • Nucleic acids research, Principles of miRNA/miRNA* function in plant MIRNA processing
    Name: Rosatti, S.; Rojas, A.; Moro, B.; Suarez, I.; Bologna, N.; Chorostecki, U.; Palatnik, J. Role: Autor Publishing date: 2024
    Start page: 8356 End page: 8369 Vol.: 52 No.: 14
    DOI: 10.1093/nar/gkae458 ISSN or title: 0305-1048
  • Briefings in Bioinformatics, sincFold: end-to-end learning of short- and long-range interactions in RNA secondary structure
    Name: Bugnon, L.; Di Persia, L.; Gerard, M.; Raad, J.; Prochetto, S.; Fenoy, E.; Chorostecki, U.; Ariel, F.; Stegmayer, G.; Milone, D. Role: Autor Publishing date: 2024
    Vol.: 25 No.: 4
    DOI: 10.1093/bib/bbae271 ISSN or title: 1477-4054
  • Frontiers in Microbiology, Probing RNA structural landscapes across Candida yeast genomes
    Name: Chorostecki, U.; Saus, E.; Gabaldón, T. Role: Autor Publishing date: 2024
    Vol.: 15
    DOI: 10.3389/fmicb.2024.1362067 ISSN or title: 1664-302X
  • EMBO Journal, The plant noncoding transcriptome: a versatile environmental sensor
    Name: Chorostecki, U.; Bologna, N.; Ariel, F. Role: Autor Publishing date: 2023
    Vol.: 42
    DOI: 10.15252/embj.2023114400 ISSN or title: 1460-2075
  • Briefings in bioinformatics, Secondary structure prediction of long noncoding RNA: review and experimental comparison of existing approaches
    Name: Bugnon, L.; Edera, A.; Prochetto, S.; Gerard, M.; Raad, J.; Fenoy, E.; Rubiolo, M.; Chorostecki, U.; Gabaldón, T.; Ariel, F.; Di Persia, L.; Milone, D.; Stegmayer, G. Role: Autor Publishing date: 2023
    Start page: 1 End page: 14 Vol.: 23 No.: 4
    DOI: 10.1093/bib/bbac205 ISSN or title: 1467-5463
  • Journal Molecular Biology, EvolClustDB: Exploring Eukaryotic Gene Clusters with Evolutionarily Conserved Genomic Neighbourhoods
    Name: Marcet, M.; Collado, I.; Fuentes, D.; Gómez, A.; Molina, M.; Garisoain, A.; Chorostecki, U.; Gabaldón, T. Role: Autor Publishing date: 2023
    Vol.: 435 No.: 14
    DOI: 10.1016/j.jmb.2023.168013 ISSN or title: 0022-2836 1089-8638
  • IUBMB life, A hybrid approach to assess the structural impact of long noncoding RNA mutations uncovers key NEAT1 interactions in colorectal cancer
    Name: Aydın, E.; Saus, E.; Chorostecki, U.; Gabaldón, T. Role: Autor Publishing date: 2023
    Start page: 566 End page: 579 Vol.: 75 No.: 7
    DOI: 10.1002/iub.2710 ISSN or title: 1521-6543
  • Nucleic acids research, PhylomeDB V5: an expanding repository for genome-wide catalogues of annotated gene phylogenies
    Name: Fuentes, D.; Molina, M.; Chorostecki, U.; Capella, S.; Marcet, M.; Gabaldón, T. Role: Autor Publishing date: 2023
    Start page: D1062 End page: D1068 Vol.: 50 No.: D1
    DOI: 10.1093/nar/gkab966 ISSN or title: 0305-1048
  • Methods in Molecular Biology, Profiling of RNA Structure at Single-Nucleotide Resolution Using nextPARS
    Name: Chorostecki, U.; Willis, J.; Saus, E.; Gabaldon, T. Role: Autor Publishing date: 2023
    Start page: 51 End page: 62 Vol.: 2284
    DOI: 10.1007/978-1-0716-1307-8_4 ISSN or title: 1940-6029 10643745
  • Computational and structural biotechnology journal, Structural characterization of NORAD reveals a stabilizing role of spacers and two new repeat units
    Name: Chorostecki, U.; Saus, E.; Gabaldón, T. Role: Autor Publishing date: 2021
    Start page: 3245 End page: 3254 Vol.: 19
    DOI: 10.1016/j.csbj.2021.05.045 ISSN or title: 2001-0370
  • Nature communications, Identification of key sequence features required for microRNA biogenesis in plants
    Name: Chorostecki, U.; Rojas, A.; Drusin, S.; Mateos, J.; Moro, B.; Bologna, N.; Bresso, E.; Schapire, A.; Rasia, R.; Moreno, D.; Palatnik, J. Role: Autor Publishing date: 2020
    Vol.: 11
    DOI: 10.1038/s41467-020-19129-6 ISSN or title: 2041-1723
  • Nucleic acids research, MetaPhOrs 2.0: integrative, phylogeny-based inference of orthology and paralogy across the tree of life
    Name: Chorostecki, U.; Molina, M.; Pryszcz, L.; Gabaldón, T. Role: Autor Publishing date: 2020
    Start page: W553 End page: W557 Vol.: 48 No.: W1
    DOI: 10.1093/nar/gkaa282 ISSN or title: 0305-1048
  • RNA biology, Transcriptomic analyses reveal groups of co-expressed, syntenic lncRNAs in four species of the genus Caenorhabditis
    Name: Pegueroles, C.; Iraola, S.; Chorostecki, U.; Ksiezopolska, E.; Saus, E.; Gabaldón, T. Role: Autor Publishing date: 2019
    Start page: 320 End page: 329 Vol.: 16 No.: 3
    DOI: 10.1080/15476286.2019.1572438 ISSN or title: 1547-6286
  • Nucleic acids research, Efficiency and precision of microRNA biogenesis modes in plants
    Name: Moro, B.; Chorostecki, U.; Arikit, S.; Suarez, I.; Höbartner, C.; Rasia, R.; Meyers, B.; Palatnik, J. Role: Autor Publishing date: 2018
    Start page: 10709 End page: 10723 Vol.: 46 No.: 20
    DOI: 10.1093/nar/gky853 ISSN or title: 0305-1048
  • Plant physiology, Spatial Control of Gene Expression by miR319-Regulated TCP Transcription Factors in Leaf Development
    Name: Bresso, E.; Chorostecki, U.; Rodriguez, R.; Palatnik, J.; Schommer, C. Role: Autor Publishing date: 2018
    Start page: 1694 End page: 1708 Vol.: 176 No.: 2
    DOI: 10.1104/pp.17.00823 ISSN or title: 0032-0889
  • Plant cell, Evolutionary Footprints Reveal Insights into Plant MicroRNA Biogenesis
    Name: Chorostecki, U.; Moro, B.; Rojas, A.; Debernardi, J.; Schapire, A.; Notredame, C.; Palatnik, J. Role: Autor Publishing date: 2017
    Start page: 1248 End page: 1261 Vol.: 29 No.: 6
    DOI: 10.1105/tpc.17.00272 ISSN or title: 1040-4651
  • Bioinformatics, comTAR: a web tool for the prediction and characterization of conserved microRNA targets in plants
    Name: Chorostecki, U.; Palatnik, J. Role: Autor Publishing date: 2014
    Start page: 2066 End page: 2067 Vol.: 30 No.: 14
    DOI: 10.1093/bioinformatics/btu147 ISSN or title: 1367-4803
  • Genome research, Multiple RNA recognition patterns during microRNA biogenesis in plants
    Name: Bologna, N.; Schapire, A.; Zhai, J.; Chorostecki, U.; Boisbouvier, J.; Meyers, B.; Palatnik, J. Role: Autor Publishing date: 2013
    Start page: 1675 End page: 1689 Vol.: 23 No.: 10
    DOI: 10.1101/gr.153387.112 ISSN or title: 1054-9803
  • Nucleic acids research, Identification of new microRNA-regulated genes by conserved targeting in plant species
    Name: Chorostecki, U.; Crosa, V.; Lodeyro, A.; Bologna, N.; Martin, A.; Carrillo, N.; Schommer, C.; Palatnik, J. Role: Autor Publishing date: 2012
    Start page: 8893 End page: 8904 Vol.: 40 No.: 18
    DOI: 10.1093/nar/gks625 ISSN or title: 0305-1048
  • CURRENT BIOLOGY, Identification of microRNA processing determinants by random mutagenesis of Arabidopsis MIR172a precursor
    Name: Mateos, J.; Bologna, N.; Chorostecki, U.; Palatnik, J. Role: Autor Publishing date: 2010
    Start page: 49 End page: 54 Vol.: 20 No.: 1
    DOI: 10.1016/j.cub.2009.10.072 ISSN or title: 1879-0445
Course 2025-2026 - Period: 01/09/2025 - 31/08/2026
  • Bachelor’s Degree
    Bachelor's Degree in Biomedical Sciences
    • - Introduction to Bioinformatics
    • - Final Degree Project
    • - External Laboratory Practices
  • Others
    Lifelong Learning Master's Degree in the Biomedical Business Management
    • - Capacidades Transversales: Gestión de Proyectos, Negociación y Comunicación
Course 2024-2025 - Period: 01/09/2024 - 31/08/2025
  • Bachelor’s Degree
    Bachelor's Degree in Biomedical Sciences
    • - Introduction to Bioinformatics
    • - Final Degree Project
Course 2023-2024 - Period: 01/09/2023 - 31/08/2024
  • Bachelor’s Degree
    Bachelor's Degree in Biomedical Sciences
    • - Bioinformatics for Omics

Academic training

PhD in Biological Sciences, NATIONAL UNIVERSITY OF ROSARIO
Degree in Computer Science, NATIONAL UNIVERSITY OF ROSARIO

Professional experience

Group Leader of the Computational RNA Biology Lab. Co-Founder & CSO Kresko RNAtech
2019 - 2022 JdC-Incorporacion fellow. Barcelona Supercomputing Centre (BSC)
2017 - 2019 MSCA-IF Fellow. Centre for Genomic Regulation (CRG)
2016 - 2017 Bunge Y Born Postdoctoral Fellow. IBR Rosario, Argentina

Publications

Articles

  • Nucleic acids research, SIREs 3.0, an improved RNA prediction tool for iron-responsive elements
    Name: Suarez, C.; Navarro, M.; Chorostecki, U.; Sánchez, M. Role: Autor Publishing date: 2025
    DOI: 10.1093/nar/gkaf390 ISSN or title: 0305-1048
  • Nucleic acids research, Principles of miRNA/miRNA* function in plant MIRNA processing
    Name: Rosatti, S.; Rojas, A.; Moro, B.; Suarez, I.; Bologna, N.; Chorostecki, U.; Palatnik, J. Role: Autor Publishing date: 2024
    Start page: 8356 End page: 8369 Vol.: 52 No.: 14
    DOI: 10.1093/nar/gkae458 ISSN or title: 0305-1048
  • Briefings in Bioinformatics, sincFold: end-to-end learning of short- and long-range interactions in RNA secondary structure
    Name: Bugnon, L.; Di Persia, L.; Gerard, M.; Raad, J.; Prochetto, S.; Fenoy, E.; Chorostecki, U.; Ariel, F.; Stegmayer, G.; Milone, D. Role: Autor Publishing date: 2024
    Vol.: 25 No.: 4
    DOI: 10.1093/bib/bbae271 ISSN or title: 1477-4054
  • Frontiers in Microbiology, Probing RNA structural landscapes across Candida yeast genomes
    Name: Chorostecki, U.; Saus, E.; Gabaldón, T. Role: Autor Publishing date: 2024
    Vol.: 15
    DOI: 10.3389/fmicb.2024.1362067 ISSN or title: 1664-302X
  • EMBO Journal, The plant noncoding transcriptome: a versatile environmental sensor
    Name: Chorostecki, U.; Bologna, N.; Ariel, F. Role: Autor Publishing date: 2023
    Vol.: 42
    DOI: 10.15252/embj.2023114400 ISSN or title: 1460-2075
  • Briefings in bioinformatics, Secondary structure prediction of long noncoding RNA: review and experimental comparison of existing approaches
    Name: Bugnon, L.; Edera, A.; Prochetto, S.; Gerard, M.; Raad, J.; Fenoy, E.; Rubiolo, M.; Chorostecki, U.; Gabaldón, T.; Ariel, F.; Di Persia, L.; Milone, D.; Stegmayer, G. Role: Autor Publishing date: 2023
    Start page: 1 End page: 14 Vol.: 23 No.: 4
    DOI: 10.1093/bib/bbac205 ISSN or title: 1467-5463
  • Journal Molecular Biology, EvolClustDB: Exploring Eukaryotic Gene Clusters with Evolutionarily Conserved Genomic Neighbourhoods
    Name: Marcet, M.; Collado, I.; Fuentes, D.; Gómez, A.; Molina, M.; Garisoain, A.; Chorostecki, U.; Gabaldón, T. Role: Autor Publishing date: 2023
    Vol.: 435 No.: 14
    DOI: 10.1016/j.jmb.2023.168013 ISSN or title: 0022-2836 1089-8638
  • IUBMB life, A hybrid approach to assess the structural impact of long noncoding RNA mutations uncovers key NEAT1 interactions in colorectal cancer
    Name: Aydın, E.; Saus, E.; Chorostecki, U.; Gabaldón, T. Role: Autor Publishing date: 2023
    Start page: 566 End page: 579 Vol.: 75 No.: 7
    DOI: 10.1002/iub.2710 ISSN or title: 1521-6543
  • Nucleic acids research, PhylomeDB V5: an expanding repository for genome-wide catalogues of annotated gene phylogenies
    Name: Fuentes, D.; Molina, M.; Chorostecki, U.; Capella, S.; Marcet, M.; Gabaldón, T. Role: Autor Publishing date: 2023
    Start page: D1062 End page: D1068 Vol.: 50 No.: D1
    DOI: 10.1093/nar/gkab966 ISSN or title: 0305-1048
  • Methods in Molecular Biology, Profiling of RNA Structure at Single-Nucleotide Resolution Using nextPARS
    Name: Chorostecki, U.; Willis, J.; Saus, E.; Gabaldon, T. Role: Autor Publishing date: 2023
    Start page: 51 End page: 62 Vol.: 2284
    DOI: 10.1007/978-1-0716-1307-8_4 ISSN or title: 1940-6029 10643745
  • Computational and structural biotechnology journal, Structural characterization of NORAD reveals a stabilizing role of spacers and two new repeat units
    Name: Chorostecki, U.; Saus, E.; Gabaldón, T. Role: Autor Publishing date: 2021
    Start page: 3245 End page: 3254 Vol.: 19
    DOI: 10.1016/j.csbj.2021.05.045 ISSN or title: 2001-0370
  • Nature communications, Identification of key sequence features required for microRNA biogenesis in plants
    Name: Chorostecki, U.; Rojas, A.; Drusin, S.; Mateos, J.; Moro, B.; Bologna, N.; Bresso, E.; Schapire, A.; Rasia, R.; Moreno, D.; Palatnik, J. Role: Autor Publishing date: 2020
    Vol.: 11
    DOI: 10.1038/s41467-020-19129-6 ISSN or title: 2041-1723
  • Nucleic acids research, MetaPhOrs 2.0: integrative, phylogeny-based inference of orthology and paralogy across the tree of life
    Name: Chorostecki, U.; Molina, M.; Pryszcz, L.; Gabaldón, T. Role: Autor Publishing date: 2020
    Start page: W553 End page: W557 Vol.: 48 No.: W1
    DOI: 10.1093/nar/gkaa282 ISSN or title: 0305-1048
  • RNA biology, Transcriptomic analyses reveal groups of co-expressed, syntenic lncRNAs in four species of the genus Caenorhabditis
    Name: Pegueroles, C.; Iraola, S.; Chorostecki, U.; Ksiezopolska, E.; Saus, E.; Gabaldón, T. Role: Autor Publishing date: 2019
    Start page: 320 End page: 329 Vol.: 16 No.: 3
    DOI: 10.1080/15476286.2019.1572438 ISSN or title: 1547-6286
  • Nucleic acids research, Efficiency and precision of microRNA biogenesis modes in plants
    Name: Moro, B.; Chorostecki, U.; Arikit, S.; Suarez, I.; Höbartner, C.; Rasia, R.; Meyers, B.; Palatnik, J. Role: Autor Publishing date: 2018
    Start page: 10709 End page: 10723 Vol.: 46 No.: 20
    DOI: 10.1093/nar/gky853 ISSN or title: 0305-1048
  • Plant physiology, Spatial Control of Gene Expression by miR319-Regulated TCP Transcription Factors in Leaf Development
    Name: Bresso, E.; Chorostecki, U.; Rodriguez, R.; Palatnik, J.; Schommer, C. Role: Autor Publishing date: 2018
    Start page: 1694 End page: 1708 Vol.: 176 No.: 2
    DOI: 10.1104/pp.17.00823 ISSN or title: 0032-0889
  • Plant cell, Evolutionary Footprints Reveal Insights into Plant MicroRNA Biogenesis
    Name: Chorostecki, U.; Moro, B.; Rojas, A.; Debernardi, J.; Schapire, A.; Notredame, C.; Palatnik, J. Role: Autor Publishing date: 2017
    Start page: 1248 End page: 1261 Vol.: 29 No.: 6
    DOI: 10.1105/tpc.17.00272 ISSN or title: 1040-4651
  • Bioinformatics, comTAR: a web tool for the prediction and characterization of conserved microRNA targets in plants
    Name: Chorostecki, U.; Palatnik, J. Role: Autor Publishing date: 2014
    Start page: 2066 End page: 2067 Vol.: 30 No.: 14
    DOI: 10.1093/bioinformatics/btu147 ISSN or title: 1367-4803
  • Genome research, Multiple RNA recognition patterns during microRNA biogenesis in plants
    Name: Bologna, N.; Schapire, A.; Zhai, J.; Chorostecki, U.; Boisbouvier, J.; Meyers, B.; Palatnik, J. Role: Autor Publishing date: 2013
    Start page: 1675 End page: 1689 Vol.: 23 No.: 10
    DOI: 10.1101/gr.153387.112 ISSN or title: 1054-9803
  • Nucleic acids research, Identification of new microRNA-regulated genes by conserved targeting in plant species
    Name: Chorostecki, U.; Crosa, V.; Lodeyro, A.; Bologna, N.; Martin, A.; Carrillo, N.; Schommer, C.; Palatnik, J. Role: Autor Publishing date: 2012
    Start page: 8893 End page: 8904 Vol.: 40 No.: 18
    DOI: 10.1093/nar/gks625 ISSN or title: 0305-1048
  • CURRENT BIOLOGY, Identification of microRNA processing determinants by random mutagenesis of Arabidopsis MIR172a precursor
    Name: Mateos, J.; Bologna, N.; Chorostecki, U.; Palatnik, J. Role: Autor Publishing date: 2010
    Start page: 49 End page: 54 Vol.: 20 No.: 1
    DOI: 10.1016/j.cub.2009.10.072 ISSN or title: 1879-0445
Course 2025-2026 - Period: 01/09/2025 - 31/08/2026
  • Bachelor’s Degree
    Bachelor's Degree in Biomedical Sciences
    • - Introduction to Bioinformatics
    • - Final Degree Project
    • - External Laboratory Practices
  • Others
    Lifelong Learning Master's Degree in the Biomedical Business Management
    • - Capacidades Transversales: Gestión de Proyectos, Negociación y Comunicación
Course 2024-2025 - Period: 01/09/2024 - 31/08/2025
  • Bachelor’s Degree
    Bachelor's Degree in Biomedical Sciences
    • - Introduction to Bioinformatics
    • - Final Degree Project
Course 2023-2024 - Period: 01/09/2023 - 31/08/2024
  • Bachelor’s Degree
    Bachelor's Degree in Biomedical Sciences
    • - Bioinformatics for Omics