Directori

OZKAN, Selen

Departament de Ciències Bàsiques

OZKAN, Selen

CV

Perfil del professor

Ciències Bàsiques, DEPARTAMENT DE CIÈNCIES BÀSIQUES. Universitat Internacional de Catalunya

Formació acadèmica

Màster Universitari en Bioinformàtica UNIVERSITAT POMPEU FABRA
Graduate Molecular Biology and Genetics ISTANBUL TECHNICAL UNIVERSITY

Experiència professional

2020 - 2022 Predoctoral researcher - Clinical and Translational Bioinformatics Research Group, Vall d’Hebron Institute of Research PhD project: Development and use of protein-specific bioinformatics tools to identify pathogenic sequence variants for proteins in clinical genome, building and testing models with supervised learning algorithms
2018 - 2019 Master thesis student Clinical and Translational Bioinformatics Research Group, Vall d’Hebron Institute of Research Exploring the power of bioinformatics tools for the molecular diagnosis of hereditary breast and ovarian cancer with random forest models

PUBLICACIONES:
Aguirre, J., Padilla, N., Özkan, S., Riera, C., Feliubadaló, L., & de la Cruz, X. (2022). Choosing variant interpretation tools for clinical applications: context matters. bioRxiv; 2022. DOI: 10.1101/2022.02.17.480823
Özkan, S., Padilla, N., & de la Cruz, X. (2021). Towards a New, Endophenotype-Based Strategy for Pathogenicity Prediction in BRCA1 and BRCA2: In Silico Modeling of the Outcome of HDR/SGE Assays for Missense Variants. International journal of molecular sciences, 22(12), 6226.
Özkan, S., Padilla, N., Moles-Fernández, A., Diez, O., Gutiérrez-Enríquez, S., & de la Cruz, X. (2021). The computational approach to variant interpretation: Principles, results, and applicability. In Clinical DNA Variant Interpretation(pp. 89-119). Academic Press
Kirchner, S. K., Ozkan, S., Musil, R., Spellmann, I., Kannayian, N., Falkai, P., Rossner M. & Papiol, S. (2020). Polygenic analysis suggests the involvement of calcium signaling in executive function in schizophrenia patients. European Archives of Psychiatry and
Clinical Neuroscience, 270(4), 425-431.
Cline, M. S., Babbi, G., Bonache, S., Cao, Y., Casadio, R., de la Cruz, X., ..., Ozkan, S., ... & ENIGMA Consortium. (2019). Assessment of blind predictions of the clinical significance of BRCA1 and BRCA2 variants. Human Mutation, 40(9), 1546-1556.
Padilla N, Moles-Fernández A, Riera C, Montalban G, Ozkan, S., Ootes L, Bonanche S, Díez O, Gutiérrez-Enríquez S, de la Cruz X. (2019) “BRCA1- and BRCA2-specific in silico tools for variants interpretation in the CAGI 5 ENIGMA challenge” Human Mutation.
https://doi.org/10.1002/humu.23802
Schulze TG, Ozkan, S. (2017) “Update on Research Into Genetics and PharmacoGenetics of Bipolar Disorder” Dusunen Adam The Journal of Psychiatry and Neurological Sciences; 30:165-169. https://doi.org/10.5350/DAJPN20173003001